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Overcoming fratricide of CD86 targeting CAR-T cells by defined logic-gate CAR strategy.

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Title: Overcoming fratricide of CD86 targeting CAR-T cells by defined logic-gate CAR strategy.
Authors: Riet T; Department I of Internal Medicine, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937, Cologne, Germany.; Translational Research for Infectious Diseases and Oncology (TRIO), University Cologne, Robert Koch Str. 21, 50931, Cologne, Germany., Lennartz S; Department I of Internal Medicine, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937, Cologne, Germany.; Translational Research for Infectious Diseases and Oncology (TRIO), University Cologne, Robert Koch Str. 21, 50931, Cologne, Germany., Bösing N; Department I of Internal Medicine, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937, Cologne, Germany.; Translational Research for Infectious Diseases and Oncology (TRIO), University Cologne, Robert Koch Str. 21, 50931, Cologne, Germany., Prinz LF; Department I of Internal Medicine, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937, Cologne, Germany.; Translational Research for Infectious Diseases and Oncology (TRIO), University Cologne, Robert Koch Str. 21, 50931, Cologne, Germany., Dähn L; Department I of Internal Medicine, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937, Cologne, Germany.; Translational Research for Infectious Diseases and Oncology (TRIO), University Cologne, Robert Koch Str. 21, 50931, Cologne, Germany., Scheid C; Department I of Internal Medicine, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937, Cologne, Germany., Hallek M; Department I of Internal Medicine, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937, Cologne, Germany., Chmielewski MM; Department I of Internal Medicine, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937, Cologne, Germany. markus.chmielewski@uk-koeln.de.; Translational Research for Infectious Diseases and Oncology (TRIO), University Cologne, Robert Koch Str. 21, 50931, Cologne, Germany. markus.chmielewski@uk-koeln.de.
Source: Experimental hematology & oncology [Exp Hematol Oncol] 2026 Jun 18; Vol. 15 (1). Date of Electronic Publication: 2026 Jun 18.
Publication Type: Letter
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101590676 Publication Model: Electronic Cited Medium: Print ISSN: 2162-3619 (Print) Linking ISSN: 21623619 NLM ISO Abbreviation: Exp Hematol Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Overcoming fratricide of CD86 targeting CAR-T cells by defined logic-gate CAR strategy.
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  Data: <searchLink fieldCode="AU" term="%22Riet+T%22">Riet T</searchLink>; Department I of Internal Medicine, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937, Cologne, Germany.; Translational Research for Infectious Diseases and Oncology (TRIO), University Cologne, Robert Koch Str. 21, 50931, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Lennartz+S%22">Lennartz S</searchLink>; Department I of Internal Medicine, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937, Cologne, Germany.; Translational Research for Infectious Diseases and Oncology (TRIO), University Cologne, Robert Koch Str. 21, 50931, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Bösing+N%22">Bösing N</searchLink>; Department I of Internal Medicine, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937, Cologne, Germany.; Translational Research for Infectious Diseases and Oncology (TRIO), University Cologne, Robert Koch Str. 21, 50931, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Prinz+LF%22">Prinz LF</searchLink>; Department I of Internal Medicine, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937, Cologne, Germany.; Translational Research for Infectious Diseases and Oncology (TRIO), University Cologne, Robert Koch Str. 21, 50931, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Dähn+L%22">Dähn L</searchLink>; Department I of Internal Medicine, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937, Cologne, Germany.; Translational Research for Infectious Diseases and Oncology (TRIO), University Cologne, Robert Koch Str. 21, 50931, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Scheid+C%22">Scheid C</searchLink>; Department I of Internal Medicine, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Hallek+M%22">Hallek M</searchLink>; Department I of Internal Medicine, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Chmielewski+MM%22">Chmielewski MM</searchLink>; Department I of Internal Medicine, University Hospital Cologne and Faculty of Medicine, University of Cologne, 50937, Cologne, Germany. markus.chmielewski@uk-koeln.de.; Translational Research for Infectious Diseases and Oncology (TRIO), University Cologne, Robert Koch Str. 21, 50931, Cologne, Germany. markus.chmielewski@uk-koeln.de.
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  Data: <searchLink fieldCode="JN" term="%22101590676%22">Experimental hematology & oncology</searchLink> [Exp Hematol Oncol] 2026 Jun 18; Vol. 15 (1). <i>Date of Electronic Publication: </i>2026 Jun 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101590676 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2162-3619 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221623619%22">21623619 </searchLink><i>NLM ISO Abbreviation: </i>Exp Hematol Oncol <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2026 Jun 18
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