Real-World Effectiveness and Safety of Tucatinib, Trastuzumab, and Capecitabine in HER2-Positive Advanced Breast Cancer: A Multicenter Portuguese Study.

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Title: Real-World Effectiveness and Safety of Tucatinib, Trastuzumab, and Capecitabine in HER2-Positive Advanced Breast Cancer: A Multicenter Portuguese Study.
Authors: Ferreira RQ; Department of Medical Oncology, Local Health Unit of São José, Academic Clinical Center, Lisbon, Portugal., Monteiro CB; Department of Medical Oncology, Local Health Unit of Santa Maria, Lisbon, Portugal., Dias AC; Department of Medical Oncology, Local Health Unit of Alto Ave, Guimarães, Portugal., Abreu F; Department of Medical Oncology, Local Health Unit of Alto Ave, Guimarães, Portugal., Darmits B; Department of Medical Oncology, Instituto Português de Oncologia de Coimbra Francisco Gentil, Coimbra, Portugal., Oura MJ; Department of Medical Oncology, Local Health Unit of São João, Porto, Portugal., Ângelo I; Department of Medical Oncology, Local Health Unit of Arco Ribeirinho, Barreiro, Portugal., Cabral J; Department of Medical Oncology, Local Health Unit of Gaia and Espinho, Espinho, Portugal., Figueiredo A; Department of Medical Oncology, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal., Ferreira R; Department of Medical Oncology, Local Health Unit of Amadora/Sintra, Sintra, Portugal., Alpuim Costa D; Oncology Functional Unit, Hospital de Cascais (Alcabideche), Cascais, Portugal., Marques MT; Department of Medical Oncology, Local Health Unit of Arrábida, Setúbal, Portugal., Pina-Cabral T; Department of Medical Oncology, Local Health Unit of Lisboa Ocidental, Lisbon, Portugal., Araújo F; Department of Medical Oncology, Local Health Unit of Santo António, Porto, Portugal., Bento S; Department of Medical Oncology, Local Health Unit of Lezíria, Santarém, Portugal., Fernandes CL; Department of Medical Oncology, Local Health Unit of Matosinhos, Matosinhos, Portugal., Santiago M; Department of Medical Oncology, Local Health Unit of Almada/Seixal, Seixal, Portugal., Silva B; Department of Medical Oncology, Local Health Unit of Loures/Odivelas, Odivelas, Portugal., Montenegro MA; Department of Medical Oncology, Local Health Unit of São José, Academic Clinical Center, Lisbon, Portugal., Simão DC; Department of Medical Oncology, Local Health Unit of São José, Academic Clinical Center, Lisbon, Portugal., Fernandes L; Department of Medical Oncology, Local Health Unit of São José, Academic Clinical Center, Lisbon, Portugal., Oliveira SD; Department of Hematology-Oncology, University Hospitals Seidman Cancer Center, Cleveland, United States.
Source: European journal of breast health [Eur J Breast Health] 2026 Jun 17; Vol. 22 (3), pp. 318-327.
Publication Type: Journal Article
Journal Info: Publisher: Galenos Publishing House Country of Publication: Turkey NLM ID: 101709357 Publication Model: Print Cited Medium: Print ISSN: 2587-0831 (Print) NLM ISO Abbreviation: Eur J Breast Health Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Real-World Effectiveness and Safety of Tucatinib, Trastuzumab, and Capecitabine in HER2-Positive Advanced Breast Cancer: A Multicenter Portuguese Study.
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  Data: <searchLink fieldCode="AU" term="%22Ferreira+RQ%22">Ferreira RQ</searchLink>; Department of Medical Oncology, Local Health Unit of São José, Academic Clinical Center, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Monteiro+CB%22">Monteiro CB</searchLink>; Department of Medical Oncology, Local Health Unit of Santa Maria, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Dias+AC%22">Dias AC</searchLink>; Department of Medical Oncology, Local Health Unit of Alto Ave, Guimarães, Portugal.<br /><searchLink fieldCode="AU" term="%22Abreu+F%22">Abreu F</searchLink>; Department of Medical Oncology, Local Health Unit of Alto Ave, Guimarães, Portugal.<br /><searchLink fieldCode="AU" term="%22Darmits+B%22">Darmits B</searchLink>; Department of Medical Oncology, Instituto Português de Oncologia de Coimbra Francisco Gentil, Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Oura+MJ%22">Oura MJ</searchLink>; Department of Medical Oncology, Local Health Unit of São João, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Ângelo+I%22">Ângelo I</searchLink>; Department of Medical Oncology, Local Health Unit of Arco Ribeirinho, Barreiro, Portugal.<br /><searchLink fieldCode="AU" term="%22Cabral+J%22">Cabral J</searchLink>; Department of Medical Oncology, Local Health Unit of Gaia and Espinho, Espinho, Portugal.<br /><searchLink fieldCode="AU" term="%22Figueiredo+A%22">Figueiredo A</searchLink>; Department of Medical Oncology, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Ferreira+R%22">Ferreira R</searchLink>; Department of Medical Oncology, Local Health Unit of Amadora/Sintra, Sintra, Portugal.<br /><searchLink fieldCode="AU" term="%22Alpuim+Costa+D%22">Alpuim Costa D</searchLink>; Oncology Functional Unit, Hospital de Cascais (Alcabideche), Cascais, Portugal.<br /><searchLink fieldCode="AU" term="%22Marques+MT%22">Marques MT</searchLink>; Department of Medical Oncology, Local Health Unit of Arrábida, Setúbal, Portugal.<br /><searchLink fieldCode="AU" term="%22Pina-Cabral+T%22">Pina-Cabral T</searchLink>; Department of Medical Oncology, Local Health Unit of Lisboa Ocidental, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Araújo+F%22">Araújo F</searchLink>; Department of Medical Oncology, Local Health Unit of Santo António, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Bento+S%22">Bento S</searchLink>; Department of Medical Oncology, Local Health Unit of Lezíria, Santarém, Portugal.<br /><searchLink fieldCode="AU" term="%22Fernandes+CL%22">Fernandes CL</searchLink>; Department of Medical Oncology, Local Health Unit of Matosinhos, Matosinhos, Portugal.<br /><searchLink fieldCode="AU" term="%22Santiago+M%22">Santiago M</searchLink>; Department of Medical Oncology, Local Health Unit of Almada/Seixal, Seixal, Portugal.<br /><searchLink fieldCode="AU" term="%22Silva+B%22">Silva B</searchLink>; Department of Medical Oncology, Local Health Unit of Loures/Odivelas, Odivelas, Portugal.<br /><searchLink fieldCode="AU" term="%22Montenegro+MA%22">Montenegro MA</searchLink>; Department of Medical Oncology, Local Health Unit of São José, Academic Clinical Center, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Simão+DC%22">Simão DC</searchLink>; Department of Medical Oncology, Local Health Unit of São José, Academic Clinical Center, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Fernandes+L%22">Fernandes L</searchLink>; Department of Medical Oncology, Local Health Unit of São José, Academic Clinical Center, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Oliveira+SD%22">Oliveira SD</searchLink>; Department of Hematology-Oncology, University Hospitals Seidman Cancer Center, Cleveland, United States.
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  Data: <searchLink fieldCode="JN" term="%22101709357%22">European journal of breast health</searchLink> [Eur J Breast Health] 2026 Jun 17; Vol. 22 (3), pp. 318-327.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Galenos+Publishing+House%22">Galenos Publishing House </searchLink><i>Country of Publication: </i>Turkey <i>NLM ID: </i>101709357 <i>Publication Model: </i>Print <i>Cited Medium: </i>Print <i>ISSN: </i>2587-0831 (Print) <i>NLM ISO Abbreviation: </i>Eur J Breast Health <i>Subsets: </i>PubMed not MEDLINE
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