The pterocarpan (+)-PTC modulates cytoskeletal proteins and induces apoptosis in metastatic castration-resistant prostate cancer: a proteomic perspective.
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| Title: | The pterocarpan (+)-PTC modulates cytoskeletal proteins and induces apoptosis in metastatic castration-resistant prostate cancer: a proteomic perspective. |
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| Authors: | de Brito Vieira Neto J; Drug Research and Development Center, Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Brazil., Moraes de Farias K; Drug Research and Development Center, Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Brazil.; Programa de Pós-Graduação em Biotecnologia, Rede Nordeste de Biotecnologia, Federal University of Ceará, Fortaleza, Brazil., Alves Sales SL; Drug Research and Development Center, Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Brazil., Melo VB; Drug Research and Development Center, Postgraduate Program in Translational Medicine, Federal University of Ceará, Fortaleza, Brazil., Nascimento Macêdo SM; Drug Research and Development Center, Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Brazil., Koscky Paier CR; Drug Research and Development Center, Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Brazil., Bezerra MJ; Drug Research and Development Center, Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Brazil.; Drug Research and Development Center, Postgraduate Program in Translational Medicine, Federal University of Ceará, Fortaleza, Brazil., Moura AA; Drug Research and Development Center, Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Brazil.; Programa de Pós-Graduação em Biotecnologia, Rede Nordeste de Biotecnologia, Federal University of Ceará, Fortaleza, Brazil.; Department of Animal Science, Federal University of Ceará, Fortaleza, Ceará, Brazil., Carvalho HF; Department of Structural and Functional Biology, Biology Institute, State University of Campinas, Campinas, Brazil., Domingos de Sousa F; Center for Experimental Biology, Universidade de Fortaleza, Fortaleza, Brazil., Aquino A; Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, Brazil., de Oliveira Monteiro AC; Graduate Program in Medical Sciences, Experimental Biology Center, University of Fortaleza, Fortaleza, Brazil., Martins-de-Souza D; Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, Brazil.; Experimental Medicine Research Cluster (EMRC), University of Campinas, Campinas, Brazil.; D'Or Institute for Research and Education (IDOR), SãoPaulo, Brazil.; INCT in Modelling Human Complex Diseases With 3D Platforms (Model3D), Conselho Nacional de Desenvolvimento Científico e Tecnológico, SãoPaulo, Brazil., Banwell MG; Institute for Advanced and Applied Chemical Synthesis, Jinan University, Zhuhai, China., Miranda Furtado CL; Department of Genetics, Ecology and Evolution, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil., Pessoa C; Drug Research and Development Center, Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Brazil.; Programa de Pós-Graduação em Biotecnologia, Rede Nordeste de Biotecnologia, Federal University of Ceará, Fortaleza, Brazil. |
| Source: | Frontiers in pharmacology [Front Pharmacol] 2026 Jun 03; Vol. 17, pp. 1770249. Date of Electronic Publication: 2026 Jun 03 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1663-9812 |
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| DOI: | 10.3389/fphar.2026.1770249 |
