CRISPR/Cas9-mediated miR-21 editing in high-grade urothelial carcinoma cells and its biological effects.

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Title: CRISPR/Cas9-mediated miR-21 editing in high-grade urothelial carcinoma cells and its biological effects.
Authors: Yi Lin Lee MC; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil., Camargo JA; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil., Caetano Vilas Boas G; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil., Silva KS; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil., Silva LP; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil., Mioshi CM; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil., Pimenta R; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil.; Precision Immunology Institute, Department of Immunology and Immunotherapy, and Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, United States., Silva IA; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil., Ramos Moreira Leite K; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil., Nahas WC; Uro-Oncology Group, Urology Department, Institute of Cancer State of São Paulo (ICESP), São Paulo, Brazil., Dos Reis ST; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil. sabrinareis@usp.br.; Moriah Institute of Science and Education (MISE), Hospital Moriah, São Paulo, Brazil. sabrinareis@usp.br.
Source: Molecular biology reports [Mol Biol Rep] 2026 Jun 19; Vol. 53 (1). Date of Electronic Publication: 2026 Jun 19.
Publication Type: Journal Article
Journal Info: Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-4978 (Electronic) Linking ISSN: 03014851 NLM ISO Abbreviation: Mol Biol Rep Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Yi+Lin+Lee+MC%22">Yi Lin Lee MC</searchLink>; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Camargo+JA%22">Camargo JA</searchLink>; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Caetano+Vilas+Boas+G%22">Caetano Vilas Boas G</searchLink>; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Silva+KS%22">Silva KS</searchLink>; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Silva+LP%22">Silva LP</searchLink>; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Mioshi+CM%22">Mioshi CM</searchLink>; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Pimenta+R%22">Pimenta R</searchLink>; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil.; Precision Immunology Institute, Department of Immunology and Immunotherapy, and Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, United States.<br /><searchLink fieldCode="AU" term="%22Silva+IA%22">Silva IA</searchLink>; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Ramos+Moreira+Leite+K%22">Ramos Moreira Leite K</searchLink>; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Nahas+WC%22">Nahas WC</searchLink>; Uro-Oncology Group, Urology Department, Institute of Cancer State of São Paulo (ICESP), São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Dos+Reis+ST%22">Dos Reis ST</searchLink>; Laboratory of Medical Investigation (LIM55), Urology Department, University of São Paulo Medical School, Av. Dr. Arnaldo 455, 2° floor, room 2145 - Cerqueira Cesar, São Paulo, Brazil. sabrinareis@usp.br.; Moriah Institute of Science and Education (MISE), Hospital Moriah, São Paulo, Brazil. sabrinareis@usp.br.
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              Text: 2026 Jun 19
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