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Osr1-expressing mesoderm contributes to lymphatic vessel assembly and complexity in the mammalian kidney.

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Title: Osr1-expressing mesoderm contributes to lymphatic vessel assembly and complexity in the mammalian kidney.
Authors: Jafree DJ; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Russell LG; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK., Stathopoulou A; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; Institute of Developmental and Regenerative Medicine, University of Oxford, Oxford, UK., O'Riordan C; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK., Rowan CJ; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, Canada., White AT; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK., Kolatsi-Joannou M; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK., Price KL; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK., Ivins S; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK., Ridge LA; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; School of Biological and Chemical Sciences, Manchester Metropolitan University, Manchester, UK., Roberts C; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; Institute of Medical and Biomedical Education, St George's University of London, London, UK., Rose A; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK., Webb S; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK., Vijayabaskar MS; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK., Chandler JC; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK., Wilson L; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK., Pomeranz G; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK., Moulding D; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK., Davis B; Central Laser Facility, Science and Technologies Facilities Council, UK Research and Innovation, Didcot, Oxfordshire, UK., Mitchell H; Mathematical Sciences Research Centre, Queen's University Belfast, Belfast, UK., Siegenthaler J; University of Colorado Anschutz Medical Campus, Department of Pediatrics, Section of Developmental Biology, Aurora, CO, USA., Haniffa M; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK; Cambridge University Hospitals Foundation Trust, Addenbrooke's Hospital, Cambridge, UK; Cambridge Institute for Therapeutic Immunology and Infectious Diseases (CIITID), University of Cambridge, Cambridge, UK., Woolf AS; School of Biological Sciences, Faculty of Biology Medicine and Health, University of Manchester, Manchester, UK., Riley PR; Institute of Developmental and Regenerative Medicine, University of Oxford, Oxford, UK., Ruhrberg C; UCL Institute of Ophthalmology, University College London, London, UK., Scambler PJ; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK., Rosenblum ND; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, Canada., Long DA; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK. Electronic address: d.long@ucl.ac.uk.
Source: Cell reports [Cell Rep] 2026 Jun 19, pp. 117560. Date of Electronic Publication: 2026 Jun 19.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
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  Data: Osr1-expressing mesoderm contributes to lymphatic vessel assembly and complexity in the mammalian kidney.
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  Data: <searchLink fieldCode="AU" term="%22Jafree+DJ%22">Jafree DJ</searchLink>; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Russell+LG%22">Russell LG</searchLink>; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Stathopoulou+A%22">Stathopoulou A</searchLink>; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; Institute of Developmental and Regenerative Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22O'Riordan+C%22">O'Riordan C</searchLink>; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Rowan+CJ%22">Rowan CJ</searchLink>; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22White+AT%22">White AT</searchLink>; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Kolatsi-Joannou+M%22">Kolatsi-Joannou M</searchLink>; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Price+KL%22">Price KL</searchLink>; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ivins+S%22">Ivins S</searchLink>; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ridge+LA%22">Ridge LA</searchLink>; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; School of Biological and Chemical Sciences, Manchester Metropolitan University, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Roberts+C%22">Roberts C</searchLink>; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; Institute of Medical and Biomedical Education, St George's University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Rose+A%22">Rose A</searchLink>; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Webb+S%22">Webb S</searchLink>; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Vijayabaskar+MS%22">Vijayabaskar MS</searchLink>; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Chandler+JC%22">Chandler JC</searchLink>; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Wilson+L%22">Wilson L</searchLink>; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Pomeranz+G%22">Pomeranz G</searchLink>; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Moulding+D%22">Moulding D</searchLink>; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Davis+B%22">Davis B</searchLink>; Central Laser Facility, Science and Technologies Facilities Council, UK Research and Innovation, Didcot, Oxfordshire, UK.<br /><searchLink fieldCode="AU" term="%22Mitchell+H%22">Mitchell H</searchLink>; Mathematical Sciences Research Centre, Queen's University Belfast, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Siegenthaler+J%22">Siegenthaler J</searchLink>; University of Colorado Anschutz Medical Campus, Department of Pediatrics, Section of Developmental Biology, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Haniffa+M%22">Haniffa M</searchLink>; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK; Cambridge University Hospitals Foundation Trust, Addenbrooke's Hospital, Cambridge, UK; Cambridge Institute for Therapeutic Immunology and Infectious Diseases (CIITID), University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Woolf+AS%22">Woolf AS</searchLink>; School of Biological Sciences, Faculty of Biology Medicine and Health, University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Riley+PR%22">Riley PR</searchLink>; Institute of Developmental and Regenerative Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Ruhrberg+C%22">Ruhrberg C</searchLink>; UCL Institute of Ophthalmology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Scambler+PJ%22">Scambler PJ</searchLink>; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Rosenblum+ND%22">Rosenblum ND</searchLink>; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Long+DA%22">Long DA</searchLink>; Developmental Biology & Cancer Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Centre for Kidney and Bladder Health, University College London, London, UK. Electronic address: d.long@ucl.ac.uk.
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