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The splicing factor hnRNPA1 promotes osimertinib resistance in lung adenocarcinoma by regulating NEDD4L alternative splicing.

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Title: The splicing factor hnRNPA1 promotes osimertinib resistance in lung adenocarcinoma by regulating NEDD4L alternative splicing.
Authors: Liang Y; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Guo Y; Guangdong Medical University, Zhanjiang, China., Huang X; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Wang Q; Guangdong Medical University, Zhanjiang, China., Wu Y; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Ye H; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Long Q; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Pang M; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Lei X; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Jiang Y; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Yin M; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Chen Y; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Zheng Y; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Xu X; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Yang Q; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Yang J; Guangdong Medical University, Zhanjiang, China., Chen J; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Chen J; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Li H; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Xie Y; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Su W; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China. suwenmei123@hotmail.com.
Source: Oncogene [Oncogene] 2026 Aug; Vol. 45 (30), pp. 3039-3052. Date of Electronic Publication: 2026 Jun 19.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The splicing factor hnRNPA1 promotes osimertinib resistance in lung adenocarcinoma by regulating NEDD4L alternative splicing.
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  Data: <searchLink fieldCode="AU" term="%22Liang+Y%22">Liang Y</searchLink>; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Guo+Y%22">Guo Y</searchLink>; Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Huang+X%22">Huang X</searchLink>; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Ye+H%22">Ye H</searchLink>; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Long+Q%22">Long Q</searchLink>; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Pang+M%22">Pang M</searchLink>; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Lei+X%22">Lei X</searchLink>; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Jiang+Y%22">Jiang Y</searchLink>; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Yin+M%22">Yin M</searchLink>; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Zheng+Y%22">Zheng Y</searchLink>; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Xu+X%22">Xu X</searchLink>; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Yang+Q%22">Yang Q</searchLink>; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Yang+J%22">Yang J</searchLink>; Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Xie+Y%22">Xie Y</searchLink>; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Su+W%22">Su W</searchLink>; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China. suwenmei123@hotmail.com.
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  Data: <searchLink fieldCode="JN" term="%228711562%22">Oncogene</searchLink> [Oncogene] 2026 Aug; Vol. 45 (30), pp. 3039-3052. <i>Date of Electronic Publication: </i>2026 Jun 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8711562 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5594 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209509232%22">09509232 </searchLink><i>NLM ISO Abbreviation: </i>Oncogene <i>Subsets: </i>MEDLINE
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