Early induction of the Rho-GEF ECT2 drives MEK/ERK oncogenic signaling in pancreatic ductal adenocarcinoma.
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| Title: | Early induction of the Rho-GEF ECT2 drives MEK/ERK oncogenic signaling in pancreatic ductal adenocarcinoma. |
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| Authors: | Al-Qasrawi D; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.; Comprehensive Cancer Center, Mayo Clinic, Jacksonville, FL, USA., Murray NN; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA., Argo RA; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA., Fleming Martinez AK; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.; Comprehensive Cancer Center, Mayo Clinic, Jacksonville, FL, USA., Pandya P; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA., Clarke AY; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.; University of North Florida, Jacksonville, FL, USA., Winter KC; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA., Krishna M; Department of Pathology/Lab Medicine, Mayo Clinic, Jacksonville, FL, USA., Storz P; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.; Comprehensive Cancer Center, Mayo Clinic, Jacksonville, FL, USA., Murray NR; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.; Comprehensive Cancer Center, Mayo Clinic, Jacksonville, FL, USA., Justilien V; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA. Justilien.verline@mayo.edu.; Comprehensive Cancer Center, Mayo Clinic, Jacksonville, FL, USA. Justilien.verline@mayo.edu. |
| Source: | Oncogene [Oncogene] 2026 Aug; Vol. 45 (30), pp. 3053-3068. Date of Electronic Publication: 2026 Jun 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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