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ECAS-Based Neuropsychological Phenotyping in Amyotrophic Lateral Sclerosis: A Retrospective Study Comparing Different Algorithms.

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Title: ECAS-Based Neuropsychological Phenotyping in Amyotrophic Lateral Sclerosis: A Retrospective Study Comparing Different Algorithms.
Authors: Poletti B; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy. b.poletti@auxologico.it.; Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, Milan, Italy. b.poletti@auxologico.it., Aiello EN; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy., Consonni M; 3rd Neurology Unit and Motor Neuron Disease Centre, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Iazzolino B; 'Rita Levi Montalcini', Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, Turin, Italy., Torre S; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy., Faltracco V; 3rd Neurology Unit and Motor Neuron Disease Centre, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Telesca A; Neuroalgology Unit, Department of Clinical Neuroscience, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.; Neurointensive Care Unit, Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Palumbo F; 'Rita Levi Montalcini', Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, Turin, Italy., Curti B; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy., De Luca G; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy., Moreschi A; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy., Frisco F; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy., Dalla Bella E; 3rd Neurology Unit and Motor Neuron Disease Centre, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Bersano E; 3rd Neurology Unit and Motor Neuron Disease Centre, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.; Department of Medical Biotechnology and Translational Medicine, Università Degli Studi Di Milano, Milan, Italy., Riva N; 3rd Neurology Unit and Motor Neuron Disease Centre, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Verde F; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy., Messina S; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy., Doretti A; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy., Maranzano A; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy., Morelli C; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy., Cappa SF; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy., Calvo A; 'Rita Levi Montalcini', Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, Turin, Italy.; Neurology 1, City of Health and Science University Hospital of Turin, Turin, Italy., Strong MJ; Molecular Medicine Group, Schulich School of Medicine and Dentistry, Robarts Research Institute, Western University, London, ON, Canada.; Department of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Department of Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada., Silani V; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center, Università degli Studi di Milano, Milan, Italy., Lauria G; 3rd Neurology Unit and Motor Neuron Disease Centre, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.; Department of Medical Biotechnology and Translational Medicine, Università Degli Studi Di Milano, Milan, Italy., Chiò A; 'Rita Levi Montalcini', Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, Turin, Italy.; Neurology 1, City of Health and Science University Hospital of Turin, Turin, Italy.; Institute of Cognitive Science and Technologies, National Research Council, Rome, Italy., Ticozzi N; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center, Università degli Studi di Milano, Milan, Italy.
Source: Neurology and therapy [Neurol Ther] 2026 Jun 20. Date of Electronic Publication: 2026 Jun 20.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: New Zealand NLM ID: 101637818 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2193-8253 (Print) Linking ISSN: 21936536 NLM ISO Abbreviation: Neurol Ther
Database: MEDLINE Ultimate
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  Data: ECAS-Based Neuropsychological Phenotyping in Amyotrophic Lateral Sclerosis: A Retrospective Study Comparing Different Algorithms.
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  Data: <searchLink fieldCode="AU" term="%22Poletti+B%22">Poletti B</searchLink>; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy. b.poletti@auxologico.it.; Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, Milan, Italy. b.poletti@auxologico.it.<br /><searchLink fieldCode="AU" term="%22Aiello+EN%22">Aiello EN</searchLink>; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Consonni+M%22">Consonni M</searchLink>; 3rd Neurology Unit and Motor Neuron Disease Centre, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Iazzolino+B%22">Iazzolino B</searchLink>; 'Rita Levi Montalcini', Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Torre+S%22">Torre S</searchLink>; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Faltracco+V%22">Faltracco V</searchLink>; 3rd Neurology Unit and Motor Neuron Disease Centre, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Telesca+A%22">Telesca A</searchLink>; Neuroalgology Unit, Department of Clinical Neuroscience, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.; Neurointensive Care Unit, Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Palumbo+F%22">Palumbo F</searchLink>; 'Rita Levi Montalcini', Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Curti+B%22">Curti B</searchLink>; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22De+Luca+G%22">De Luca G</searchLink>; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Moreschi+A%22">Moreschi A</searchLink>; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Frisco+F%22">Frisco F</searchLink>; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Dalla+Bella+E%22">Dalla Bella E</searchLink>; 3rd Neurology Unit and Motor Neuron Disease Centre, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bersano+E%22">Bersano E</searchLink>; 3rd Neurology Unit and Motor Neuron Disease Centre, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.; Department of Medical Biotechnology and Translational Medicine, Università Degli Studi Di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Riva+N%22">Riva N</searchLink>; 3rd Neurology Unit and Motor Neuron Disease Centre, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Verde+F%22">Verde F</searchLink>; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Messina+S%22">Messina S</searchLink>; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Doretti+A%22">Doretti A</searchLink>; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Maranzano+A%22">Maranzano A</searchLink>; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Morelli+C%22">Morelli C</searchLink>; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cappa+SF%22">Cappa SF</searchLink>; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Calvo+A%22">Calvo A</searchLink>; 'Rita Levi Montalcini', Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, Turin, Italy.; Neurology 1, City of Health and Science University Hospital of Turin, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Strong+MJ%22">Strong MJ</searchLink>; Molecular Medicine Group, Schulich School of Medicine and Dentistry, Robarts Research Institute, Western University, London, ON, Canada.; Department of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Department of Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Silani+V%22">Silani V</searchLink>; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center, Università degli Studi di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Lauria+G%22">Lauria G</searchLink>; 3rd Neurology Unit and Motor Neuron Disease Centre, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.; Department of Medical Biotechnology and Translational Medicine, Università Degli Studi Di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Chiò+A%22">Chiò A</searchLink>; 'Rita Levi Montalcini', Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, Turin, Italy.; Neurology 1, City of Health and Science University Hospital of Turin, Turin, Italy.; Institute of Cognitive Science and Technologies, National Research Council, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ticozzi+N%22">Ticozzi N</searchLink>; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center, Università degli Studi di Milano, Milan, Italy.
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