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Pharmacological effect of rhCC16 on COPD: anti-senescence via the PI3K-AKT-mTOR pathway.

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Title: Pharmacological effect of rhCC16 on COPD: anti-senescence via the PI3K-AKT-mTOR pathway.
Authors: Gao R; Department of Pulmonary and Critical Care Medicine, the First Hospital of Shanxi Medical University; NHC Key Laboratory of Pneumoconiosis;, Shanxi Key Laboratory of Chronic Respiratory Diseases and pneumoconiosis, No. 85 Jiefang South Road, Taiyuan, 030001, Shanxi, China., Wu S; School of Basic Medicine, Basic Medical Science Center, Shanxi Medical University, No. 55 Wenhua Street, Jinzhong, 030600, Shanxi, China., Zhang CL; Department of Pulmonary and Critical Care Medicine, the First Hospital of Shanxi Medical University; NHC Key Laboratory of Pneumoconiosis;, Shanxi Key Laboratory of Chronic Respiratory Diseases and pneumoconiosis, No. 85 Jiefang South Road, Taiyuan, 030001, Shanxi, China., Liu CF; Department of Pulmonary and Critical Care Medicine, the First Hospital of Shanxi Medical University; NHC Key Laboratory of Pneumoconiosis;, Shanxi Key Laboratory of Chronic Respiratory Diseases and pneumoconiosis, No. 85 Jiefang South Road, Taiyuan, 030001, Shanxi, China., Li T; Department of Pulmonary and Critical Care Medicine, the First Hospital of Shanxi Medical University; NHC Key Laboratory of Pneumoconiosis;, Shanxi Key Laboratory of Chronic Respiratory Diseases and pneumoconiosis, No. 85 Jiefang South Road, Taiyuan, 030001, Shanxi, China., Guo M; Laboratory Animal Center, Shanxi Medical University, No. 55 Wenhua Street, Shanxi, 030600,, Jinzhong,, China., Chen ZY; Laboratory Animal Center, Shanxi Medical University, No. 55 Wenhua Street, Shanxi, 030600,, Jinzhong,, China., Wang HL; School of Basic Medicine, Basic Medical Science Center, Shanxi Medical University, No. 55 Wenhua Street, Jinzhong, 030600, Shanxi, China. longwty@sxmu.edu.cn., Pang M; Department of Pulmonary and Critical Care Medicine, the First Hospital of Shanxi Medical University; NHC Key Laboratory of Pneumoconiosis;, Shanxi Key Laboratory of Chronic Respiratory Diseases and pneumoconiosis, No. 85 Jiefang South Road, Taiyuan, 030001, Shanxi, China. pangminsdyy@sxmu.edu.cn.
Source: Molecular and cellular biochemistry [Mol Cell Biochem] 2026 Jun 20. Date of Electronic Publication: 2026 Jun 20.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4919 (Electronic) Linking ISSN: 03008177 NLM ISO Abbreviation: Mol Cell Biochem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pharmacological effect of rhCC16 on COPD: anti-senescence via the PI3K-AKT-mTOR pathway.
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  Data: <searchLink fieldCode="AU" term="%22Gao+R%22">Gao R</searchLink>; Department of Pulmonary and Critical Care Medicine, the First Hospital of Shanxi Medical University; NHC Key Laboratory of Pneumoconiosis;, Shanxi Key Laboratory of Chronic Respiratory Diseases and pneumoconiosis, No. 85 Jiefang South Road, Taiyuan, 030001, Shanxi, China.<br /><searchLink fieldCode="AU" term="%22Wu+S%22">Wu S</searchLink>; School of Basic Medicine, Basic Medical Science Center, Shanxi Medical University, No. 55 Wenhua Street, Jinzhong, 030600, Shanxi, China.<br /><searchLink fieldCode="AU" term="%22Zhang+CL%22">Zhang CL</searchLink>; Department of Pulmonary and Critical Care Medicine, the First Hospital of Shanxi Medical University; NHC Key Laboratory of Pneumoconiosis;, Shanxi Key Laboratory of Chronic Respiratory Diseases and pneumoconiosis, No. 85 Jiefang South Road, Taiyuan, 030001, Shanxi, China.<br /><searchLink fieldCode="AU" term="%22Liu+CF%22">Liu CF</searchLink>; Department of Pulmonary and Critical Care Medicine, the First Hospital of Shanxi Medical University; NHC Key Laboratory of Pneumoconiosis;, Shanxi Key Laboratory of Chronic Respiratory Diseases and pneumoconiosis, No. 85 Jiefang South Road, Taiyuan, 030001, Shanxi, China.<br /><searchLink fieldCode="AU" term="%22Li+T%22">Li T</searchLink>; Department of Pulmonary and Critical Care Medicine, the First Hospital of Shanxi Medical University; NHC Key Laboratory of Pneumoconiosis;, Shanxi Key Laboratory of Chronic Respiratory Diseases and pneumoconiosis, No. 85 Jiefang South Road, Taiyuan, 030001, Shanxi, China.<br /><searchLink fieldCode="AU" term="%22Guo+M%22">Guo M</searchLink>; Laboratory Animal Center, Shanxi Medical University, No. 55 Wenhua Street, Shanxi, 030600,, Jinzhong,, China.<br /><searchLink fieldCode="AU" term="%22Chen+ZY%22">Chen ZY</searchLink>; Laboratory Animal Center, Shanxi Medical University, No. 55 Wenhua Street, Shanxi, 030600,, Jinzhong,, China.<br /><searchLink fieldCode="AU" term="%22Wang+HL%22">Wang HL</searchLink>; School of Basic Medicine, Basic Medical Science Center, Shanxi Medical University, No. 55 Wenhua Street, Jinzhong, 030600, Shanxi, China. longwty@sxmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Pang+M%22">Pang M</searchLink>; Department of Pulmonary and Critical Care Medicine, the First Hospital of Shanxi Medical University; NHC Key Laboratory of Pneumoconiosis;, Shanxi Key Laboratory of Chronic Respiratory Diseases and pneumoconiosis, No. 85 Jiefang South Road, Taiyuan, 030001, Shanxi, China. pangminsdyy@sxmu.edu.cn.
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        Value: 10.1007/s11010-026-05611-0
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        Text: English
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              Text: 2026 Jun 20
              Type: published
              Y: 2026
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