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Newly identified invasion drivers define the tumor front in oral squamous cell carcinoma.

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Title: Newly identified invasion drivers define the tumor front in oral squamous cell carcinoma.
Authors: Flores G; Department of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, IA, USA. gflrs@uiowa.edu.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA. gflrs@uiowa.edu., Uaroon S; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA., Garay JAR; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA., Vanneste M; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.; Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA, USA., Riordan JD; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.; Department of Anatomy and Cell Biology, University of Iowa, Iowa City, IA, USA., Dupuy AJ; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.; Department of Anatomy and Cell Biology, University of Iowa, Iowa City, IA, USA., Thiel KW; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.; Department of Obstetrics and Gynecology, University of Iowa, Iowa City, IA, USA., Colling KE; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.; Department of Obstetrics and Gynecology, University of Iowa, Iowa City, IA, USA., Stipp CS; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.; Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA, USA.; Department of Biology, University of Iowa, Iowa City, IA, USA., Lin LC; Iowa NeuroBank Core, Iowa Neuroscience Institute, Carver College of Medicine, Iowa City, IA, USA., Hollis B; Iowa NeuroBank Core, Iowa Neuroscience Institute, Carver College of Medicine, Iowa City, IA, USA., Leidinger MR; University of Iowa Institute for Vision Research, Iowa City, IA, USA., Chen SJT; Department of Pathology, University of Iowa Hospitals & Clinics, Iowa City, IA, USA., Graham LM; Department of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, IA, USA.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA., Knudtson KL; Iowa Institute of Human Genetics, Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Chimenti MS; Iowa Institute of Human Genetics, Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Ratcliff JA; Iowa Institute of Human Genetics, Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Mehdi Z; Carver College of Medicine, University of Iowa, Iowa City, IA, USA., McElliott MC; Department of Otolaryngology-Head & Neck Surgery, University of Michigan, Ann Arbor, MI, USA., Anderson ER; Department of Biology, University of Iowa, Iowa City, IA, USA., Henry MD; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.; Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA, USA., Heft Neal ME; Department of Otolaryngology-Head & Neck Surgery, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA., Brenner JC; Department of Otolaryngology-Head & Neck Surgery, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA., Buchakjian MR; Department of Otolaryngology-Head & Neck Surgery, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA.
Source: Cell death discovery [Cell Death Discov] 2026 Jun 20. Date of Electronic Publication: 2026 Jun 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov
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  Data: Newly identified invasion drivers define the tumor front in oral squamous cell carcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Flores+G%22">Flores G</searchLink>; Department of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, IA, USA. gflrs@uiowa.edu.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA. gflrs@uiowa.edu.<br /><searchLink fieldCode="AU" term="%22Uaroon+S%22">Uaroon S</searchLink>; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Garay+JAR%22">Garay JAR</searchLink>; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Vanneste+M%22">Vanneste M</searchLink>; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.; Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Riordan+JD%22">Riordan JD</searchLink>; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.; Department of Anatomy and Cell Biology, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Dupuy+AJ%22">Dupuy AJ</searchLink>; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.; Department of Anatomy and Cell Biology, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Thiel+KW%22">Thiel KW</searchLink>; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.; Department of Obstetrics and Gynecology, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Colling+KE%22">Colling KE</searchLink>; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.; Department of Obstetrics and Gynecology, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Stipp+CS%22">Stipp CS</searchLink>; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.; Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA, USA.; Department of Biology, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Lin+LC%22">Lin LC</searchLink>; Iowa NeuroBank Core, Iowa Neuroscience Institute, Carver College of Medicine, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Hollis+B%22">Hollis B</searchLink>; Iowa NeuroBank Core, Iowa Neuroscience Institute, Carver College of Medicine, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Leidinger+MR%22">Leidinger MR</searchLink>; University of Iowa Institute for Vision Research, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+SJT%22">Chen SJT</searchLink>; Department of Pathology, University of Iowa Hospitals & Clinics, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Graham+LM%22">Graham LM</searchLink>; Department of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, IA, USA.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Knudtson+KL%22">Knudtson KL</searchLink>; Iowa Institute of Human Genetics, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Chimenti+MS%22">Chimenti MS</searchLink>; Iowa Institute of Human Genetics, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Ratcliff+JA%22">Ratcliff JA</searchLink>; Iowa Institute of Human Genetics, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Mehdi+Z%22">Mehdi Z</searchLink>; Carver College of Medicine, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22McElliott+MC%22">McElliott MC</searchLink>; Department of Otolaryngology-Head & Neck Surgery, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Anderson+ER%22">Anderson ER</searchLink>; Department of Biology, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Henry+MD%22">Henry MD</searchLink>; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.; Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Heft+Neal+ME%22">Heft Neal ME</searchLink>; Department of Otolaryngology-Head & Neck Surgery, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Brenner+JC%22">Brenner JC</searchLink>; Department of Otolaryngology-Head & Neck Surgery, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Buchakjian+MR%22">Buchakjian MR</searchLink>; Department of Otolaryngology-Head & Neck Surgery, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA.
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