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Network pharmacology and molecular dynamics simulations reveal shared mechanisms and myopia-specific targets of atropine in myopia and dry eye disease.

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Title: Network pharmacology and molecular dynamics simulations reveal shared mechanisms and myopia-specific targets of atropine in myopia and dry eye disease.
Authors: Lin M; National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.; School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China., Shu W; National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.; School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China., Hua G; National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.; School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China., Duan Z; National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.; School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China., Qu J; National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China. qujia@eye.ac.cn.; School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China. qujia@eye.ac.cn., Hu L; National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China. huliang@eye.ac.cn.; School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China. huliang@eye.ac.cn.
Source: Eye and vision (London, England) [Eye Vis (Lond)] 2026 Jun 22; Vol. 13 (1). Date of Electronic Publication: 2026 Jun 22.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101664982 Publication Model: Electronic Cited Medium: Print ISSN: 2326-0254 (Print) Linking ISSN: 23260254 NLM ISO Abbreviation: Eye Vis (Lond) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Network pharmacology and molecular dynamics simulations reveal shared mechanisms and myopia-specific targets of atropine in myopia and dry eye disease.
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  Data: <searchLink fieldCode="AU" term="%22Lin+M%22">Lin M</searchLink>; National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.; School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Shu+W%22">Shu W</searchLink>; National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.; School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Hua+G%22">Hua G</searchLink>; National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.; School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Duan+Z%22">Duan Z</searchLink>; National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.; School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Qu+J%22">Qu J</searchLink>; National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China. qujia@eye.ac.cn.; School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China. qujia@eye.ac.cn.<br /><searchLink fieldCode="AU" term="%22Hu+L%22">Hu L</searchLink>; National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China. huliang@eye.ac.cn.; School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China. huliang@eye.ac.cn.
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  Data: <searchLink fieldCode="JN" term="%22101664982%22">Eye and vision (London, England)</searchLink> [Eye Vis (Lond)] 2026 Jun 22; Vol. 13 (1). <i>Date of Electronic Publication: </i>2026 Jun 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101664982 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2326-0254 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223260254%22">23260254 </searchLink><i>NLM ISO Abbreviation: </i>Eye Vis (Lond) <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1186/s40662-026-00493-1
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      – TitleFull: Network pharmacology and molecular dynamics simulations reveal shared mechanisms and myopia-specific targets of atropine in myopia and dry eye disease.
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              Text: 2026 Jun 22
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