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Blood-based proteomic signature of amyloidosis: identification of novel regulators of amyloid load.

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Title: Blood-based proteomic signature of amyloidosis: identification of novel regulators of amyloid load.
Authors: Chen Y; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA., Duggan MR; Laboratory of Behavioral Neuroscience, National Institute on Aging, Baltimore, Maryland, USA., Timsina J; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA., Xu Y; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA., Western D; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA., Gong K; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA., Liu M; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA., Budde J; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA., Schindler SE; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA., Morris JC; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA., Holtzman DM; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA., Benzinger TLS; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA., Gordon BA; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA., Moqri M; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Ibanez L; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.; Hope Center for Neurological Disorders, Washington University, St. Louis, Missouri, USA., Walker KA; Laboratory of Behavioral Neuroscience, National Institute on Aging, Baltimore, Maryland, USA., Cruchaga C; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.; Hope Center for Neurological Disorders, Washington University, St. Louis, Missouri, USA.; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., Ali M; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.
Corporate Authors: Knight Alzheimer Disease Research Center (Knight‐ADRC); Knight Alzheimer's Disease Research Center, Washington University, St. Louis, Missouri, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 Jun; Vol. 22 (6), pp. e71611.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Duggan+MR%22">Duggan MR</searchLink>; Laboratory of Behavioral Neuroscience, National Institute on Aging, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Timsina+J%22">Timsina J</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Western+D%22">Western D</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Gong+K%22">Gong K</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Liu+M%22">Liu M</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Budde+J%22">Budde J</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Schindler+SE%22">Schindler SE</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Morris+JC%22">Morris JC</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Holtzman+DM%22">Holtzman DM</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Benzinger+TLS%22">Benzinger TLS</searchLink>; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Gordon+BA%22">Gordon BA</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Moqri+M%22">Moqri M</searchLink>; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Ibanez+L%22">Ibanez L</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.; Hope Center for Neurological Disorders, Washington University, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Walker+KA%22">Walker KA</searchLink>; Laboratory of Behavioral Neuroscience, National Institute on Aging, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Cruchaga+C%22">Cruchaga C</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.; Hope Center for Neurological Disorders, Washington University, St. Louis, Missouri, USA.; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Ali+M%22">Ali M</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.
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