A Phase III, Randomized, Double-Blind, Active-Controlled, Multicenter Study Evaluating the Safety and Efficacy of Tegoprazan for the Prevention of Peptic Ulcer in Patients on Continuous Long-Term Treatment with Nonsteroidal Anti-Inflammatory Drugs.
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| Title: | A Phase III, Randomized, Double-Blind, Active-Controlled, Multicenter Study Evaluating the Safety and Efficacy of Tegoprazan for the Prevention of Peptic Ulcer in Patients on Continuous Long-Term Treatment with Nonsteroidal Anti-Inflammatory Drugs. |
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| Authors: | Kim SG; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea., Kim TO; Department of Internal Medicine, Inje University Haeundae Paik Hospital, Busan, Korea., Jung SW; Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Korea., Min BH; Department of Medicine, Samsung Medical Center, Seoul, Korea., Oh JH; Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea., Kim HS; Department of Internal Medicine, Wonju Severance Christian Hospital, Wonju, Korea., Lee GH; Department of Gastroenterology, Ajou University School of Medicine, Suwon, Korea., Song JH; Department of Internal Medicine, Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea., Sung IK; Department of Internal Medicine, Konkuk University Medical Center, Seoul, Korea., Cho YS; Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea., Choi SC; Department of Internal Medicine, Wonkwang University Hospital, Iksan, Korea., Lim YJ; Department of Internal Medicine, Dongguk University Ilsan Hospital, Ilsan, Korea., Kim BW; Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea., Shin CM; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea., Huh CW; Department of Internal Medicine, Yongin Severance Hospital, Yongin, Korea., Kim JW; Department of Internal Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Korea., Kim KO; Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea., Cho YK; Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea., Lee OY; Department of Internal Medicine, Hanyang University Hospital, Seoul, Korea., Moon JS; Department of Internal Medicine, Inje University Sanggye Paik Hospital, Seoul, Korea., Lee HW; Department of Internal Medicine, Gimpo Woori Hospital, Gimpo, Korea., Jung HY; Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Shin WG; Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.; Institute for Liver and Digestive Disease, Hallym University College of Medicine, Chuncheon, Korea., Kim JG; Department of Internal Medicine, Chung-Ang University Hospital, Seoul, Korea., Lee JY; Department of Internal Medicine, Keimyung University Dongsan Hospital, Daegu, Korea., Han SJ; Department of Internal Medicine, Seoul Bumin Hospital, Seoul, Korea., Kim SW; Department of Internal Medicine, Jeonbuk National University Hospital, Jeonju, Korea., Cho JH; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea., Lim H; Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea., Kim TH; Department of Internal Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea., Park MI; Department of Internal Medicine, Kosin University Gospel Hospital, Busan, Korea., Baik GH; Department of Internal Medicine, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon, Korea., Cha RR; Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Gyeongsang National University School of Medicine, Changwon, Korea., Lee SK; Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea., Kim JJ; Department of Gastroenterology, Uijeongbu Eulji Medical Center, Eulji University, Uijeongbu, Korea. |
| Source: | Gut and liver [Gut Liver] 2026 Jul 15; Vol. 20 (4), pp. 551-561. Date of Electronic Publication: 2026 Jun 22. |
| Publication Type: | Journal Article; Multicenter Study; Randomized Controlled Trial; Clinical Trial, Phase III; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Editorial Office of Gut and Liver Country of Publication: Korea (South) NLM ID: 101316452 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2005-1212 (Electronic) Linking ISSN: 19762283 NLM ISO Abbreviation: Gut Liver Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42325011 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A Phase III, Randomized, Double-Blind, Active-Controlled, Multicenter Study Evaluating the Safety and Efficacy of Tegoprazan for the Prevention of Peptic Ulcer in Patients on Continuous Long-Term Treatment with Nonsteroidal Anti-Inflammatory Drugs. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Kim+SG%22">Kim SG</searchLink>; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+TO%22">Kim TO</searchLink>; Department of Internal Medicine, Inje University Haeundae Paik Hospital, Busan, Korea.<br /><searchLink fieldCode="AU" term="%22Jung+SW%22">Jung SW</searchLink>; Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Korea.<br /><searchLink fieldCode="AU" term="%22Min+BH%22">Min BH</searchLink>; Department of Medicine, Samsung Medical Center, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Oh+JH%22">Oh JH</searchLink>; Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+HS%22">Kim HS</searchLink>; Department of Internal Medicine, Wonju Severance Christian Hospital, Wonju, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+GH%22">Lee GH</searchLink>; Department of Gastroenterology, Ajou University School of Medicine, Suwon, Korea.<br /><searchLink fieldCode="AU" term="%22Song+JH%22">Song JH</searchLink>; Department of Internal Medicine, Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Sung+IK%22">Sung IK</searchLink>; Department of Internal Medicine, Konkuk University Medical Center, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Cho+YS%22">Cho YS</searchLink>; Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.<br /><searchLink fieldCode="AU" term="%22Choi+SC%22">Choi SC</searchLink>; Department of Internal Medicine, Wonkwang University Hospital, Iksan, Korea.<br /><searchLink fieldCode="AU" term="%22Lim+YJ%22">Lim YJ</searchLink>; Department of Internal Medicine, Dongguk University Ilsan Hospital, Ilsan, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+BW%22">Kim BW</searchLink>; Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea.<br /><searchLink fieldCode="AU" term="%22Shin+CM%22">Shin CM</searchLink>; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.<br /><searchLink fieldCode="AU" term="%22Huh+CW%22">Huh CW</searchLink>; Department of Internal Medicine, Yongin Severance Hospital, Yongin, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JW%22">Kim JW</searchLink>; Department of Internal Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+KO%22">Kim KO</searchLink>; Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea.<br /><searchLink fieldCode="AU" term="%22Cho+YK%22">Cho YK</searchLink>; Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+OY%22">Lee OY</searchLink>; Department of Internal Medicine, Hanyang University Hospital, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Moon+JS%22">Moon JS</searchLink>; Department of Internal Medicine, Inje University Sanggye Paik Hospital, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+HW%22">Lee HW</searchLink>; Department of Internal Medicine, Gimpo Woori Hospital, Gimpo, Korea.<br /><searchLink fieldCode="AU" term="%22Jung+HY%22">Jung HY</searchLink>; Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Shin+WG%22">Shin WG</searchLink>; Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.; Institute for Liver and Digestive Disease, Hallym University College of Medicine, Chuncheon, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JG%22">Kim JG</searchLink>; Department of Internal Medicine, Chung-Ang University Hospital, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JY%22">Lee JY</searchLink>; Department of Internal Medicine, Keimyung University Dongsan Hospital, Daegu, Korea.<br /><searchLink fieldCode="AU" term="%22Han+SJ%22">Han SJ</searchLink>; Department of Internal Medicine, Seoul Bumin Hospital, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SW%22">Kim SW</searchLink>; Department of Internal Medicine, Jeonbuk National University Hospital, Jeonju, Korea.<br /><searchLink fieldCode="AU" term="%22Cho+JH%22">Cho JH</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea.<br /><searchLink fieldCode="AU" term="%22Lim+H%22">Lim H</searchLink>; Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+TH%22">Kim TH</searchLink>; Department of Internal Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea.<br /><searchLink fieldCode="AU" term="%22Park+MI%22">Park MI</searchLink>; Department of Internal Medicine, Kosin University Gospel Hospital, Busan, Korea.<br /><searchLink fieldCode="AU" term="%22Baik+GH%22">Baik GH</searchLink>; Department of Internal Medicine, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon, Korea.<br /><searchLink fieldCode="AU" term="%22Cha+RR%22">Cha RR</searchLink>; Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Gyeongsang National University School of Medicine, Changwon, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SK%22">Lee SK</searchLink>; Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JJ%22">Kim JJ</searchLink>; Department of Gastroenterology, Uijeongbu Eulji Medical Center, Eulji University, Uijeongbu, Korea. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101316452%22">Gut and liver</searchLink> [Gut Liver] 2026 Jul 15; Vol. 20 (4), pp. 551-561. <i>Date of Electronic Publication: </i>2026 Jun 22. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Multicenter Study; Randomized Controlled Trial; Clinical Trial, Phase III; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Editorial+Office+of+Gut+and+Liver%22">Editorial Office of Gut and Liver </searchLink><i>Country of Publication: </i>Korea (South) <i>NLM ID: </i>101316452 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2005-1212 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219762283%22">19762283 </searchLink><i>NLM ISO Abbreviation: </i>Gut Liver <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42325011 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.5009/gnl260057 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 551 Titles: – TitleFull: A Phase III, Randomized, Double-Blind, Active-Controlled, Multicenter Study Evaluating the Safety and Efficacy of Tegoprazan for the Prevention of Peptic Ulcer in Patients on Continuous Long-Term Treatment with Nonsteroidal Anti-Inflammatory Drugs. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kim SG – PersonEntity: Name: NameFull: Kim TO – PersonEntity: Name: NameFull: Jung SW – PersonEntity: Name: NameFull: Min BH – PersonEntity: Name: NameFull: Oh JH – PersonEntity: Name: NameFull: Kim HS – PersonEntity: Name: NameFull: Lee GH – PersonEntity: Name: NameFull: Song JH – PersonEntity: Name: NameFull: Sung IK – PersonEntity: Name: NameFull: Cho YS – PersonEntity: Name: NameFull: Choi SC – PersonEntity: Name: NameFull: Lim YJ – PersonEntity: Name: NameFull: Kim BW – PersonEntity: Name: NameFull: Shin CM – PersonEntity: Name: NameFull: Huh CW – PersonEntity: Name: NameFull: Kim JW – PersonEntity: Name: NameFull: Kim KO – PersonEntity: Name: NameFull: Cho YK – PersonEntity: Name: NameFull: Lee OY – PersonEntity: Name: NameFull: Moon JS – PersonEntity: Name: NameFull: Lee HW – PersonEntity: Name: NameFull: Jung HY – PersonEntity: Name: NameFull: Shin WG – PersonEntity: Name: NameFull: Kim JG – PersonEntity: Name: NameFull: Lee JY – PersonEntity: Name: NameFull: Han SJ – PersonEntity: Name: NameFull: Kim SW – PersonEntity: Name: NameFull: Cho JH – PersonEntity: Name: NameFull: Lim H – PersonEntity: Name: NameFull: Kim TH – PersonEntity: Name: NameFull: Park MI – PersonEntity: Name: NameFull: Baik GH – PersonEntity: Name: NameFull: Cha RR – PersonEntity: Name: NameFull: Lee SK – PersonEntity: Name: NameFull: Kim JJ IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 07 Text: 2026 Jul 15 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2005-1212 Numbering: – Type: volume Value: 20 – Type: issue Value: 4 Titles: – TitleFull: Gut and liver Type: main |
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