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CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumor Promoting Activity.

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Title: CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumor Promoting Activity.
Authors: Jung M; Institute For Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Beer A; Institute For Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Ghosh S; Leibniz-Institut Für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany., Pylaeva E; Department of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Alshaar B; Leibniz-Institut Für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany., Tertel T; Institute For Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Leimkühler NB; Department of Hematology and Stem Cell Transplantation, West-German Cancer Center, University Hospital Essen, Essen, Germany., Schroeder T; Department of Hematology and Stem Cell Transplantation, West-German Cancer Center, University Hospital Essen, Essen, Germany., Gronewold J; Department of Neurology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Hagemann N; Department of Neurology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Mohamud Yusuf A; Department of Neurology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Frank B; Department of Neurology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Zhang Y; Department of Neurology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Nagel D; Institute For Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Schloeßer K; Leibniz-Institut Für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany., Karsch L; Institute For Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Hedtfeld E; Institute For Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Lohmann S; Institute For Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Blank K; Institute For Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Kraus A; Institute For Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Krumbein M; Department of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Kabankova N; Department of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Wang H; Leibniz-Institut Für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany.; Academy for Multidisciplinary Studies, Capital Normal University, Beijing, China., Bader A; Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-Universität München, Munich, Germany., Richter M; Institute For Experimental Pathology, Centre of Molecular Biology of Inflammation, University of Münster, Münster, Germany., Zhang F; Institute For Experimental Pathology, Centre of Molecular Biology of Inflammation, University of Münster, Münster, Germany., Chevre R; Institute For Experimental Pathology, Centre of Molecular Biology of Inflammation, University of Münster, Münster, Germany., Giebel B; Institute For Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Lang S; Department of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.; Partner Site Düsseldorf/Essen, German Cancer Consortium (DKTK), Essen, Germany., Grüneboom A; Leibniz-Institut Für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany., Maier-Begandt D; Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-Universität München, Munich, Germany., Hasenberg A; Institute For Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Soehnlein O; Institute For Experimental Pathology, Centre of Molecular Biology of Inflammation, University of Münster, Münster, Germany., Reinhardt HC; Department of Hematology and Stem Cell Transplantation, West-German Cancer Center, University Hospital Essen, Essen, Germany.; West German Cancer Center, University Hospital Essen, Essen, Germany.; Center For Molecular Biotechnology, University Hospital Essen, Essen, Germany., Heiles S; Leibniz-Institut Für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany.; Faculty of Chemistry, University of Duisburg-Essen, Essen, Germany., Chen J; Leibniz-Institut Für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany., Jablonska J; Department of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.; Partner Site Düsseldorf/Essen, German Cancer Consortium (DKTK), Essen, Germany., Sickmann A; Leibniz-Institut Für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany.; Medical Faculty, Ruhr-Universität Bochum, Bochum, Germany., Hermann DM; Department of Neurology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Gunzer M; Institute For Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany.; Leibniz-Institut Für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany.
Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2026 Jun 22, pp. e76236. Date of Electronic Publication: 2026 Jun 22.
Publication Type: Journal Article
Journal Info: Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Jung+M%22">Jung M</searchLink>; Institute For Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Beer+A%22">Beer A</searchLink>; Institute For Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Ghosh+S%22">Ghosh S</searchLink>; Leibniz-Institut Für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany.<br /><searchLink fieldCode="AU" term="%22Pylaeva+E%22">Pylaeva E</searchLink>; Department of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Alshaar+B%22">Alshaar B</searchLink>; Leibniz-Institut Für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany.<br /><searchLink fieldCode="AU" term="%22Tertel+T%22">Tertel T</searchLink>; Institute For Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Leimkühler+NB%22">Leimkühler NB</searchLink>; 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Institute For Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Kraus+A%22">Kraus A</searchLink>; Institute For Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Krumbein+M%22">Krumbein M</searchLink>; Department of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Kabankova+N%22">Kabankova N</searchLink>; Department of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Leibniz-Institut Für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany.; Academy for Multidisciplinary Studies, Capital Normal University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Bader+A%22">Bader A</searchLink>; Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-Universität München, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Richter+M%22">Richter M</searchLink>; Institute For Experimental Pathology, Centre of Molecular Biology of Inflammation, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Zhang+F%22">Zhang F</searchLink>; Institute For Experimental Pathology, Centre of Molecular Biology of Inflammation, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Chevre+R%22">Chevre R</searchLink>; Institute For Experimental Pathology, Centre of Molecular Biology of Inflammation, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Giebel+B%22">Giebel B</searchLink>; Institute For Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Lang+S%22">Lang S</searchLink>; Department of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.; Partner Site Düsseldorf/Essen, German Cancer Consortium (DKTK), Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Grüneboom+A%22">Grüneboom A</searchLink>; 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