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Minimally invasive characterization of peripheral blood measurable residual disease in multiple myeloma using high-sensitivity detection of ctDNA by next-generation sequencing.

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Title: Minimally invasive characterization of peripheral blood measurable residual disease in multiple myeloma using high-sensitivity detection of ctDNA by next-generation sequencing.
Authors: Buenache N; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain., Lasa M; Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA) Universidad de Navarra Pamplona Spain., Arroyo A; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain., González C; Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA) Universidad de Navarra Pamplona Spain., Haertle L; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain.; Department of Medicine III, Technical University of Munich, School of Medicine and Health TUM University Hospital Munich Germany.; TranslaTUM, Center for Translational Cancer Research Technical University of Munich Munich Germany., Ruiz-Heredia Y; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain., Ayala R; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain., Alonso R; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain., Martín-Muñoz A; Altum Sequencing Co. Madrid Spain., Rosa-Rosa JM; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain., González V; Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca, Salamanca (IBSAL) Universidad de Salamanca Salamanca Spain., Calasanz MJ; Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA) Universidad de Navarra Pamplona Spain., Rodríguez-Otero P; Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA) Universidad de Navarra Pamplona Spain., Rosiñol L; Amyloidosis and Myeloma Unit, Department of Hematology, IDIBAPS Hospital Clínic de Barcelona Barcelona Spain., De Arriba F; Servicio de Hematología. Hospital General Universitario Morales Meseguer. Instituto Murciano de Investigación Biosanitaria (IMIB-Pascual Parrilla) Universidad de Murcia Murcia Spain., Ocio EM; Hospital Universitario Marqués de Valdecilla (IDIVAL), Universidad de Cantabria Santander Spain., Oriol A; Institut Català d'Oncologia i Institut Josep Carreras Hospital Germans Trias i Pujol, Badalona Barcelona Spain., González Y; Institut d'Oncologia Dr. Josep Trueta Girona Spain., Sureda A; Institut Català D'Oncologia, Hospital Duran i Reynals, Institut d'Investigacio Biomedica de Bellvitge (IDIBELL) Universitat de Barcelona Barcelona Spain., Lakhwani S; Hospital Universitario de Canarias Santa Cruz de Tenerife Spain., Clavero ME; Hospital Virgen de las Nieves Granada Spain., Ibáñez A; Complejo Hospitalario Universitario de Albacete Albacete Spain., Gómez C; Hospital Universitario de Galdakao Vizcaya Spain., Orfao A; Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca, Salamanca (IBSAL) Universidad de Salamanca Salamanca Spain., Mateos MV; Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca, Salamanca (IBSAL) Universidad de Salamanca Salamanca Spain., Lahuerta JJ; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain., Cedena MT; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain., Bladé J; Amyloidosis and Myeloma Unit, Department of Hematology, IDIBAPS Hospital Clínic de Barcelona Barcelona Spain., San Miguel J; Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA) Universidad de Navarra Pamplona Spain., Puig N; Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca, Salamanca (IBSAL) Universidad de Salamanca Salamanca Spain., Paiva B; Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA) Universidad de Navarra Pamplona Spain., Martínez-López J; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain.
Source: HemaSphere [Hemasphere] 2026 Jun 18; Vol. 10 (6), pp. e70405. Date of Electronic Publication: 2026 Jun 18 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101740619 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-9241 (Electronic) Linking ISSN: 25729241 NLM ISO Abbreviation: Hemasphere Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Minimally invasive characterization of peripheral blood measurable residual disease in multiple myeloma using high-sensitivity detection of ctDNA by next-generation sequencing.
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  Data: <searchLink fieldCode="AU" term="%22Buenache+N%22">Buenache N</searchLink>; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Lasa+M%22">Lasa M</searchLink>; Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA) Universidad de Navarra Pamplona Spain.<br /><searchLink fieldCode="AU" term="%22Arroyo+A%22">Arroyo A</searchLink>; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain.<br /><searchLink fieldCode="AU" term="%22González+C%22">González C</searchLink>; Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA) Universidad de Navarra Pamplona Spain.<br /><searchLink fieldCode="AU" term="%22Haertle+L%22">Haertle L</searchLink>; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain.; Department of Medicine III, Technical University of Munich, School of Medicine and Health TUM University Hospital Munich Germany.; TranslaTUM, Center for Translational Cancer Research Technical University of Munich Munich Germany.<br /><searchLink fieldCode="AU" term="%22Ruiz-Heredia+Y%22">Ruiz-Heredia Y</searchLink>; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Ayala+R%22">Ayala R</searchLink>; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Alonso+R%22">Alonso R</searchLink>; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Martín-Muñoz+A%22">Martín-Muñoz A</searchLink>; Altum Sequencing Co. Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Rosa-Rosa+JM%22">Rosa-Rosa JM</searchLink>; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain.<br /><searchLink fieldCode="AU" term="%22González+V%22">González V</searchLink>; Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca, Salamanca (IBSAL) Universidad de Salamanca Salamanca Spain.<br /><searchLink fieldCode="AU" term="%22Calasanz+MJ%22">Calasanz MJ</searchLink>; Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA) Universidad de Navarra Pamplona Spain.<br /><searchLink fieldCode="AU" term="%22Rodríguez-Otero+P%22">Rodríguez-Otero P</searchLink>; Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA) Universidad de Navarra Pamplona Spain.<br /><searchLink fieldCode="AU" term="%22Rosiñol+L%22">Rosiñol L</searchLink>; Amyloidosis and Myeloma Unit, Department of Hematology, IDIBAPS Hospital Clínic de Barcelona Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22De+Arriba+F%22">De Arriba F</searchLink>; Servicio de Hematología. Hospital General Universitario Morales Meseguer. Instituto Murciano de Investigación Biosanitaria (IMIB-Pascual Parrilla) Universidad de Murcia Murcia Spain.<br /><searchLink fieldCode="AU" term="%22Ocio+EM%22">Ocio EM</searchLink>; Hospital Universitario Marqués de Valdecilla (IDIVAL), Universidad de Cantabria Santander Spain.<br /><searchLink fieldCode="AU" term="%22Oriol+A%22">Oriol A</searchLink>; Institut Català d'Oncologia i Institut Josep Carreras Hospital Germans Trias i Pujol, Badalona Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22González+Y%22">González Y</searchLink>; Institut d'Oncologia Dr. Josep Trueta Girona Spain.<br /><searchLink fieldCode="AU" term="%22Sureda+A%22">Sureda A</searchLink>; Institut Català D'Oncologia, Hospital Duran i Reynals, Institut d'Investigacio Biomedica de Bellvitge (IDIBELL) Universitat de Barcelona Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Lakhwani+S%22">Lakhwani S</searchLink>; Hospital Universitario de Canarias Santa Cruz de Tenerife Spain.<br /><searchLink fieldCode="AU" term="%22Clavero+ME%22">Clavero ME</searchLink>; Hospital Virgen de las Nieves Granada Spain.<br /><searchLink fieldCode="AU" term="%22Ibáñez+A%22">Ibáñez A</searchLink>; Complejo Hospitalario Universitario de Albacete Albacete Spain.<br /><searchLink fieldCode="AU" term="%22Gómez+C%22">Gómez C</searchLink>; Hospital Universitario de Galdakao Vizcaya Spain.<br /><searchLink fieldCode="AU" term="%22Orfao+A%22">Orfao A</searchLink>; Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca, Salamanca (IBSAL) Universidad de Salamanca Salamanca Spain.<br /><searchLink fieldCode="AU" term="%22Mateos+MV%22">Mateos MV</searchLink>; Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca, Salamanca (IBSAL) Universidad de Salamanca Salamanca Spain.<br /><searchLink fieldCode="AU" term="%22Lahuerta+JJ%22">Lahuerta JJ</searchLink>; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Cedena+MT%22">Cedena MT</searchLink>; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Bladé+J%22">Bladé J</searchLink>; Amyloidosis and Myeloma Unit, Department of Hematology, IDIBAPS Hospital Clínic de Barcelona Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22San+Miguel+J%22">San Miguel J</searchLink>; Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA) Universidad de Navarra Pamplona Spain.<br /><searchLink fieldCode="AU" term="%22Puig+N%22">Puig N</searchLink>; Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca, Salamanca (IBSAL) Universidad de Salamanca Salamanca Spain.<br /><searchLink fieldCode="AU" term="%22Paiva+B%22">Paiva B</searchLink>; Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA) Universidad de Navarra Pamplona Spain.<br /><searchLink fieldCode="AU" term="%22Martínez-López+J%22">Martínez-López J</searchLink>; Hematological Malignancies Clinical Research Unit, Hospital Universitario 12 de Octubre Universidad Complutense Madrid Spain.
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