Host Genetic Regulation of NLRP3 Inflammasome Cytokines Reveals Immune and Vascular Pathways in HIV.

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Title: Host Genetic Regulation of NLRP3 Inflammasome Cytokines Reveals Immune and Vascular Pathways in HIV.
Authors: Chung R; Center for Computational Biology, University of California Berkeley, Berkeley, CA., Chalasani NS; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA., Barbehenn AS; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA., Lundgren E; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA., Savur S; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA., Shome S; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA., Sheikhzadeh CH; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA., Sarvadhavabhatla S; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA., Donaire MS; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA., Pae V; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA., Chu X; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD., Winder D; Cellular Translational Research Core, Clinical Translational Sciences Institute, University of Utah, Salt Lake City, UT., Maguire CT; Cellular Translational Research Core, Clinical Translational Sciences Institute, University of Utah, Salt Lake City, UT., Topal S; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD., Ganesan A; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD.; Division of Infectious Diseases, Walter Reed National Military Medical Center, Bethesda, MD., Yabes JM; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD.; Division of Infectious Diseases, Brooke Army Medical Center, Fort Sam Houston, Texas., Larson DT; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD.; Division of Infectious Diseases, Naval Medical Center San Diego, San Diego, CA., Lalani T; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD.; Division of Infectious Diseases, Naval Medical Center Portsmouth, Portsmouth, VA., Ewers EC; Division of Infectious Diseases, Tripler Army Medical Center, Honolulu, HI., Colombo RE; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD.; Infectious Disease Service, Madigan Army Medical Center, Tacoma, WA., Dugan E; Gladstone Institutes, San Francisco, CA, USA., Rathore U; Gladstone Institutes, San Francisco, CA, USA., Marson A; Gladstone Institutes, San Francisco, CA, USA., Agan BK; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD., Tomalka JA; Department of Pathology and Laboratory Medicine, Emory School of Medicine, Atlanta, GA., Sekaly RP; Department of Pathology and Laboratory Medicine, Emory School of Medicine, Atlanta, GA., Ioannidis NM; Center for Computational Biology, University of California Berkeley, Berkeley, CA., Lee SA; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2026 Jun 10. Date of Electronic Publication: 2026 Jun 10.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Host Genetic Regulation of NLRP3 Inflammasome Cytokines Reveals Immune and Vascular Pathways in HIV.
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  Data: <searchLink fieldCode="AU" term="%22Chung+R%22">Chung R</searchLink>; Center for Computational Biology, University of California Berkeley, Berkeley, CA.<br /><searchLink fieldCode="AU" term="%22Chalasani+NS%22">Chalasani NS</searchLink>; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Barbehenn+AS%22">Barbehenn AS</searchLink>; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Lundgren+E%22">Lundgren E</searchLink>; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Savur+S%22">Savur S</searchLink>; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Shome+S%22">Shome S</searchLink>; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Sheikhzadeh+CH%22">Sheikhzadeh CH</searchLink>; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Sarvadhavabhatla+S%22">Sarvadhavabhatla S</searchLink>; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Donaire+MS%22">Donaire MS</searchLink>; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Pae+V%22">Pae V</searchLink>; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Chu+X%22">Chu X</searchLink>; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Winder+D%22">Winder D</searchLink>; Cellular Translational Research Core, Clinical Translational Sciences Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Maguire+CT%22">Maguire CT</searchLink>; Cellular Translational Research Core, Clinical Translational Sciences Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Topal+S%22">Topal S</searchLink>; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Ganesan+A%22">Ganesan A</searchLink>; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD.; Division of Infectious Diseases, Walter Reed National Military Medical Center, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Yabes+JM%22">Yabes JM</searchLink>; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD.; Division of Infectious Diseases, Brooke Army Medical Center, Fort Sam Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Larson+DT%22">Larson DT</searchLink>; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD.; Division of Infectious Diseases, Naval Medical Center San Diego, San Diego, CA.<br /><searchLink fieldCode="AU" term="%22Lalani+T%22">Lalani T</searchLink>; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD.; Division of Infectious Diseases, Naval Medical Center Portsmouth, Portsmouth, VA.<br /><searchLink fieldCode="AU" term="%22Ewers+EC%22">Ewers EC</searchLink>; Division of Infectious Diseases, Tripler Army Medical Center, Honolulu, HI.<br /><searchLink fieldCode="AU" term="%22Colombo+RE%22">Colombo RE</searchLink>; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD.; Infectious Disease Service, Madigan Army Medical Center, Tacoma, WA.<br /><searchLink fieldCode="AU" term="%22Dugan+E%22">Dugan E</searchLink>; Gladstone Institutes, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rathore+U%22">Rathore U</searchLink>; Gladstone Institutes, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Marson+A%22">Marson A</searchLink>; Gladstone Institutes, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Agan+BK%22">Agan BK</searchLink>; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Tomalka+JA%22">Tomalka JA</searchLink>; Department of Pathology and Laboratory Medicine, Emory School of Medicine, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Sekaly+RP%22">Sekaly RP</searchLink>; Department of Pathology and Laboratory Medicine, Emory School of Medicine, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Ioannidis+NM%22">Ioannidis NM</searchLink>; Center for Computational Biology, University of California Berkeley, Berkeley, CA.<br /><searchLink fieldCode="AU" term="%22Lee+SA%22">Lee SA</searchLink>; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA.
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