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Defining the Human Nucleus Pulposus Microenvironment and Its Impact on Cell Matrix Synthesis and Metabolic Activity.

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Title: Defining the Human Nucleus Pulposus Microenvironment and Its Impact on Cell Matrix Synthesis and Metabolic Activity.
Authors: Wilson N; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, The University of Dublin Dublin Ireland.; Discipline of Mechanical, Manufacturing and Biomedical Engineering, School of Engineering, Trinity College Dublin, The University of Dublin Dublin Ireland.; Advanced Materials and Bioengineering Research (AMBER) Centre, Royal College of Surgeons in Ireland & Trinity College Dublin, The University of Dublin Dublin Ireland., Néill TN; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, The University of Dublin Dublin Ireland.; Discipline of Mechanical, Manufacturing and Biomedical Engineering, School of Engineering, Trinity College Dublin, The University of Dublin Dublin Ireland.; Advanced Materials and Bioengineering Research (AMBER) Centre, Royal College of Surgeons in Ireland & Trinity College Dublin, The University of Dublin Dublin Ireland., McDonnell J; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, The University of Dublin Dublin Ireland.; Discipline of Mechanical, Manufacturing and Biomedical Engineering, School of Engineering, Trinity College Dublin, The University of Dublin Dublin Ireland.; Advanced Materials and Bioengineering Research (AMBER) Centre, Royal College of Surgeons in Ireland & Trinity College Dublin, The University of Dublin Dublin Ireland.; National Spinal Injuries Unit Mater Misericordiae University Hospital Dublin Ireland., McDonnell E; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, The University of Dublin Dublin Ireland.; Discipline of Mechanical, Manufacturing and Biomedical Engineering, School of Engineering, Trinity College Dublin, The University of Dublin Dublin Ireland.; Advanced Materials and Bioengineering Research (AMBER) Centre, Royal College of Surgeons in Ireland & Trinity College Dublin, The University of Dublin Dublin Ireland., Darwish S; National Spinal Injuries Unit Mater Misericordiae University Hospital Dublin Ireland.; School of Medicine, University College Dublin Dublin Ireland., Butler JS; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, The University of Dublin Dublin Ireland.; National Spinal Injuries Unit Mater Misericordiae University Hospital Dublin Ireland.; School of Medicine, University College Dublin Dublin Ireland., Buckley CT; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, The University of Dublin Dublin Ireland.; Discipline of Mechanical, Manufacturing and Biomedical Engineering, School of Engineering, Trinity College Dublin, The University of Dublin Dublin Ireland.; Advanced Materials and Bioengineering Research (AMBER) Centre, Royal College of Surgeons in Ireland & Trinity College Dublin, The University of Dublin Dublin Ireland.; Tissue Engineering Research Group, Department of Anatomy and Regenerative Medicine Royal College of Surgeons in Ireland Dublin Ireland.
Source: JOR spine [JOR Spine] 2026 Jun 20; Vol. 9 (2), pp. e70201. Date of Electronic Publication: 2026 Jun 20 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Wiley Periodicals, Inc Country of Publication: United States NLM ID: 101722350 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-1143 (Electronic) Linking ISSN: 25721143 NLM ISO Abbreviation: JOR Spine Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Wilson+N%22">Wilson N</searchLink>; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, The University of Dublin Dublin Ireland.; Discipline of Mechanical, Manufacturing and Biomedical Engineering, School of Engineering, Trinity College Dublin, The University of Dublin Dublin Ireland.; Advanced Materials and Bioengineering Research (AMBER) Centre, Royal College of Surgeons in Ireland & Trinity College Dublin, The University of Dublin Dublin Ireland.<br /><searchLink fieldCode="AU" term="%22Néill+TN%22">Néill TN</searchLink>; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, The University of Dublin Dublin Ireland.; Discipline of Mechanical, Manufacturing and Biomedical Engineering, School of Engineering, Trinity College Dublin, The University of Dublin Dublin Ireland.; Advanced Materials and Bioengineering Research (AMBER) Centre, Royal College of Surgeons in Ireland & Trinity College Dublin, The University of Dublin Dublin Ireland.<br /><searchLink fieldCode="AU" term="%22McDonnell+J%22">McDonnell J</searchLink>; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, The University of Dublin Dublin Ireland.; Discipline of Mechanical, Manufacturing and Biomedical Engineering, School of Engineering, Trinity College Dublin, The University of Dublin Dublin Ireland.; Advanced Materials and Bioengineering Research (AMBER) Centre, Royal College of Surgeons in Ireland & Trinity College Dublin, The University of Dublin Dublin Ireland.; National Spinal Injuries Unit Mater Misericordiae University Hospital Dublin Ireland.<br /><searchLink fieldCode="AU" term="%22McDonnell+E%22">McDonnell E</searchLink>; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, The University of Dublin Dublin Ireland.; Discipline of Mechanical, Manufacturing and Biomedical Engineering, School of Engineering, Trinity College Dublin, The University of Dublin Dublin Ireland.; Advanced Materials and Bioengineering Research (AMBER) Centre, Royal College of Surgeons in Ireland & Trinity College Dublin, The University of Dublin Dublin Ireland.<br /><searchLink fieldCode="AU" term="%22Darwish+S%22">Darwish S</searchLink>; National Spinal Injuries Unit Mater Misericordiae University Hospital Dublin Ireland.; School of Medicine, University College Dublin Dublin Ireland.<br /><searchLink fieldCode="AU" term="%22Butler+JS%22">Butler JS</searchLink>; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, The University of Dublin Dublin Ireland.; National Spinal Injuries Unit Mater Misericordiae University Hospital Dublin Ireland.; School of Medicine, University College Dublin Dublin Ireland.<br /><searchLink fieldCode="AU" term="%22Buckley+CT%22">Buckley CT</searchLink>; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, The University of Dublin Dublin Ireland.; Discipline of Mechanical, Manufacturing and Biomedical Engineering, School of Engineering, Trinity College Dublin, The University of Dublin Dublin Ireland.; Advanced Materials and Bioengineering Research (AMBER) Centre, Royal College of Surgeons in Ireland & Trinity College Dublin, The University of Dublin Dublin Ireland.; Tissue Engineering Research Group, Department of Anatomy and Regenerative Medicine Royal College of Surgeons in Ireland Dublin Ireland.
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              Text: 2026 Jun 20
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