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Age-inappropriate white matter injury reveals hidden cerebral small vessel disease burden and mortality risk.

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Title: Age-inappropriate white matter injury reveals hidden cerebral small vessel disease burden and mortality risk.
Authors: Lee PL; Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan., Ou Yang WY; Division of Cerebrovascular Disease, Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Chou KH; Brain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Neuroscience, National Yang Ming Chiao Tung University, Taipei, Taiwan., Lee WJ; Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Family Medicine, Taipei Veterans General Hospital Yuanshan Branch, Yilan County, Taiwan., Kuo CY; Brain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Neuroscience, National Yang Ming Chiao Tung University, Taipei, Taiwan., Lin SH; Division of Cerebrovascular Disease, Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Chen LK; Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Center for Geriatric and Gerontology, Taipei Veterans General Hospital, Taipei, Taiwan.; Taipei Municipal Gan-Dau Hospital (managed by Taipei Veterans General Hospital), Taipei, Taiwan., Lin CP; Brain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Neuroscience, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Education and Research, Taipei City Hospital, Taipei, Taiwan., Chung CP; Division of Cerebrovascular Disease, Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Source: Cerebral circulation - cognition and behavior [Cereb Circ Cogn Behav] 2026 Jun 06; Vol. 11, pp. 100548. Date of Electronic Publication: 2026 Jun 06 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101774849 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-2450 (Electronic) Linking ISSN: 26662450 NLM ISO Abbreviation: Cereb Circ Cogn Behav Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Age-inappropriate white matter injury reveals hidden cerebral small vessel disease burden and mortality risk.
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  Data: <searchLink fieldCode="AU" term="%22Lee+PL%22">Lee PL</searchLink>; Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ou+Yang+WY%22">Ou Yang WY</searchLink>; Division of Cerebrovascular Disease, Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chou+KH%22">Chou KH</searchLink>; Brain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Neuroscience, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+WJ%22">Lee WJ</searchLink>; Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Family Medicine, Taipei Veterans General Hospital Yuanshan Branch, Yilan County, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+CY%22">Kuo CY</searchLink>; Brain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Neuroscience, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+SH%22">Lin SH</searchLink>; Division of Cerebrovascular Disease, Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+LK%22">Chen LK</searchLink>; Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Center for Geriatric and Gerontology, Taipei Veterans General Hospital, Taipei, Taiwan.; Taipei Municipal Gan-Dau Hospital (managed by Taipei Veterans General Hospital), Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+CP%22">Lin CP</searchLink>; Brain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Neuroscience, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Education and Research, Taipei City Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chung+CP%22">Chung CP</searchLink>; Division of Cerebrovascular Disease, Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101774849%22">Cerebral circulation - cognition and behavior</searchLink> [Cereb Circ Cogn Behav] 2026 Jun 06; Vol. 11, pp. 100548. <i>Date of Electronic Publication: </i>2026 Jun 06 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+B%2EV%22">Elsevier B.V </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101774849 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2666-2450 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226662450%22">26662450 </searchLink><i>NLM ISO Abbreviation: </i>Cereb Circ Cogn Behav <i>Subsets: </i>PubMed not MEDLINE
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      – Type: doi
        Value: 10.1016/j.cccb.2026.100548
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      – Code: eng
        Text: English
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            – D: 06
              M: 06
              Text: 2026 Jun 06
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