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USP18 Impacts Cisplatin Resistance in Ovarian Cancer Cells by Modulating DNA Repair.

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Title: USP18 Impacts Cisplatin Resistance in Ovarian Cancer Cells by Modulating DNA Repair.
Authors: Corno C; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy., Costantino M; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy., Pettinari P; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy., Mirra L; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy., Stucchi S; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy., Arrighetti N; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy., Perta N; Polytechnic University of Marche, Department of Life and Environmental Science, via Brecce Bianche, 60131 Ancona, Italy., Di Muccio G; Polytechnic University of Marche, Department of Life and Environmental Science, via Brecce Bianche, 60131 Ancona, Italy., Robin M; Early Clinical Trial Unit, Medical Oncology Department, Institut régional du Cancer Montpellier, Inserm U1194, Montpellier University, France., Beretta GL; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy., Corna E; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy., Carenini N; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy., Cleris L; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy., Colombo D; Department of Medical Biotechnology and Translational Medicine, University of Milan, via Saldini 50, 20133 Milan, Italy., Luison E; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milano, Italy., Ciniselli CM; Unit of Bioinformatics and Biostatistics, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133 Milan, Italy., Lecchi M; Unit of Bioinformatics and Biostatistics, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133 Milan, Italy., Verderio P; Unit of Bioinformatics and Biostatistics, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133 Milan, Italy., Figini M; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milano, Italy., Linder S; Department of Biomedical and Clinical Sciences (BKV), SE-581 83, Linköping, Sweden.; Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden., Tosi D; Early Clinical Trial Unit, Medical Oncology Department, Institut régional du Cancer Montpellier, Inserm U1194, Montpellier University, France.; Fondazione Gianni Bonadonna, via Bertani 14, 20154 Milan, Italy., La Teana A; Polytechnic University of Marche, Department of Life and Environmental Science, via Brecce Bianche, 60131 Ancona, Italy., D'Arcy P; Department of Biomedical and Clinical Sciences (BKV), SE-581 83, Linköping, Sweden., Perego P; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy.
Source: International journal of biological sciences [Int J Biol Sci] 2026 May 29; Vol. 22 (11), pp. 5780-5798. Date of Electronic Publication: 2026 May 29 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Ivyspring International Country of Publication: Australia NLM ID: 101235568 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-2288 (Electronic) Linking ISSN: 14492288 NLM ISO Abbreviation: Int J Biol Sci Subsets: MEDLINE
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  Data: USP18 Impacts Cisplatin Resistance in Ovarian Cancer Cells by Modulating DNA Repair.
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  Data: <searchLink fieldCode="AU" term="%22Corno+C%22">Corno C</searchLink>; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Costantino+M%22">Costantino M</searchLink>; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pettinari+P%22">Pettinari P</searchLink>; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mirra+L%22">Mirra L</searchLink>; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Stucchi+S%22">Stucchi S</searchLink>; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Arrighetti+N%22">Arrighetti N</searchLink>; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Perta+N%22">Perta N</searchLink>; Polytechnic University of Marche, Department of Life and Environmental Science, via Brecce Bianche, 60131 Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Muccio+G%22">Di Muccio G</searchLink>; Polytechnic University of Marche, Department of Life and Environmental Science, via Brecce Bianche, 60131 Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Robin+M%22">Robin M</searchLink>; Early Clinical Trial Unit, Medical Oncology Department, Institut régional du Cancer Montpellier, Inserm U1194, Montpellier University, France.<br /><searchLink fieldCode="AU" term="%22Beretta+GL%22">Beretta GL</searchLink>; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Corna+E%22">Corna E</searchLink>; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Carenini+N%22">Carenini N</searchLink>; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cleris+L%22">Cleris L</searchLink>; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Colombo+D%22">Colombo D</searchLink>; Department of Medical Biotechnology and Translational Medicine, University of Milan, via Saldini 50, 20133 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Luison+E%22">Luison E</searchLink>; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Ciniselli+CM%22">Ciniselli CM</searchLink>; Unit of Bioinformatics and Biostatistics, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Lecchi+M%22">Lecchi M</searchLink>; Unit of Bioinformatics and Biostatistics, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Verderio+P%22">Verderio P</searchLink>; Unit of Bioinformatics and Biostatistics, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Figini+M%22">Figini M</searchLink>; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133 Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Linder+S%22">Linder S</searchLink>; Department of Biomedical and Clinical Sciences (BKV), SE-581 83, Linköping, Sweden.; 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