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A modular framework for automated segmentation and analysis of AFM imaging of chromatin organization.

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Title: A modular framework for automated segmentation and analysis of AFM imaging of chromatin organization.
Authors: Sørensen EW; Department of Chemistry, University of Copenhagen, 2100 Copenhagen, Denmark.; NNF Center for Optimized Oligo Escape and Control of Disease, University of Copenhagen, 2100 Copenhagen, Denmark.; NNF Center for 4D Cellular Dynamics, University of Copenhagen, 2100 Copenhagen, Denmark.; Program in Cellular and Molecular Medicine and Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA 02115, United States., Pangeni S; Program in Cellular and Molecular Medicine and Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA 02115, United States.; Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218, United States., Merino Urteaga R; Program in Cellular and Molecular Medicine and Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA 02115, United States.; Department of Biology, Johns Hopkins University, Baltimore, MD 21218, United States., Murray PJ; Program in Cellular and Molecular Medicine and Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA 02115, United States.; Department of Biology, Johns Hopkins University, Baltimore, MD 21218, United States., Rudnizky S; Program in Cellular and Molecular Medicine and Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA 02115, United States.; Department of Pediatrics, Harvard Medical School, Boston, MA 02115, United States., Liao TW; Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218, United States., Rashid F; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University, Baltimore, MD 21218, United States., Hwang J; Program in Cellular and Molecular Medicine and Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA 02115, United States.; Department of Pediatrics, Harvard Medical School, Boston, MA 02115, United States., Yamadi M; Department of Biology, Johns Hopkins University, Baltimore, MD 21218, United States., Feng XA; Department of Biology, Johns Hopkins University, Baltimore, MD 21218, United States., Zähringer J; Program in Cellular and Molecular Medicine and Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA 02115, United States.; Department of Pediatrics, Harvard Medical School, Boston, MA 02115, United States., Gu S; Program in Cellular and Molecular Medicine and Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA 02115, United States.; Department of Pediatrics, Harvard Medical School, Boston, MA 02115, United States., Davidson IF; Research Institute of Molecular Pathology, Vienna BioCenter, Vienna, 1030, Austria., Caccianini L; Department of Biology, Massachusetts Institute of Technology and Howard Hughes Medical Institute, Cambridge, MA 02139, United States., Osorio-Valeriano M; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, United States., Farnung L; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, United States., Vos SM; Department of Biology, Massachusetts Institute of Technology and Howard Hughes Medical Institute, Cambridge, MA 02139, United States., Peters JM; Research Institute of Molecular Pathology, Vienna BioCenter, Vienna, 1030, Austria., Berger J; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University, Baltimore, MD 21218, United States., Wu C; Department of Biology, Johns Hopkins University, Baltimore, MD 21218, United States., Hatzakis NS; Department of Chemistry, University of Copenhagen, 2100 Copenhagen, Denmark.; NNF Center for Optimized Oligo Escape and Control of Disease, University of Copenhagen, 2100 Copenhagen, Denmark.; NNF Center for 4D Cellular Dynamics, University of Copenhagen, 2100 Copenhagen, Denmark., Kirkegaard JB; Department of Computer Science, University of Copenhagen, 2100 Copenhagen, Denmark., Ha T; Program in Cellular and Molecular Medicine and Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA 02115, United States.; Department of Pediatrics, Harvard Medical School, Boston, MA 02115, United States.
Source: Nucleic acids research [Nucleic Acids Res] 2026 Jun 22; Vol. 54 (12).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A modular framework for automated segmentation and analysis of AFM imaging of chromatin organization.
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Research Institute of Molecular Pathology, Vienna BioCenter, Vienna, 1030, Austria.<br /><searchLink fieldCode="AU" term="%22Berger+J%22">Berger J</searchLink>; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University, Baltimore, MD 21218, United States.<br /><searchLink fieldCode="AU" term="%22Wu+C%22">Wu C</searchLink>; Department of Biology, Johns Hopkins University, Baltimore, MD 21218, United States.<br /><searchLink fieldCode="AU" term="%22Hatzakis+NS%22">Hatzakis NS</searchLink>; Department of Chemistry, University of Copenhagen, 2100 Copenhagen, Denmark.; NNF Center for Optimized Oligo Escape and Control of Disease, University of Copenhagen, 2100 Copenhagen, Denmark.; NNF Center for 4D Cellular Dynamics, University of Copenhagen, 2100 Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Kirkegaard+JB%22">Kirkegaard JB</searchLink>; Department of Computer Science, University of Copenhagen, 2100 Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Ha+T%22">Ha T</searchLink>; 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