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Addition of blood-stage antibody enhances anti-sporozoite antibody protection in a humanized mouse model of Plasmodium falciparum infection.

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Title: Addition of blood-stage antibody enhances anti-sporozoite antibody protection in a humanized mouse model of Plasmodium falciparum infection.
Authors: Kirtley P; Oregon Health and Science University, Vaccine and Gene Therapy Institute, Beaverton, OR, USA., Martinson T; Oregon Health and Science University, Vaccine and Gene Therapy Institute, Beaverton, OR, USA., Donnellan FR; Department of Paediatrics and Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK., Aleshnick M; Oregon Health and Science University, Vaccine and Gene Therapy Institute, Beaverton, OR, USA., Nielsen K; Oregon Health and Science University, Vaccine and Gene Therapy Institute, Beaverton, OR, USA., Mayer BT; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Borate B; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Huang TJ; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Pipini D; Department of Paediatrics and Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK., Rigby CA; Department of Paediatrics and Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK., Quinkert D; Department of Paediatrics and Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK., Silk SE; Department of Paediatrics and Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK., Minassian AM; Department of Paediatrics and Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK; NIHR Oxford Biomedical Research Centre, Oxford, UK., McHugh K; Department of Paediatrics and Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK., Draper SJ; Department of Paediatrics and Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK; NIHR Oxford Biomedical Research Centre, Oxford, UK., Wilder BK; Oregon Health and Science University, Vaccine and Gene Therapy Institute, Beaverton, OR, USA. Electronic address: wilderb@ohsu.edu.
Source: Cell reports [Cell Rep] 2026 Jun 22; Vol. 45 (7), pp. 117573. Date of Electronic Publication: 2026 Jun 22.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
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  Data: Addition of blood-stage antibody enhances anti-sporozoite antibody protection in a humanized mouse model of Plasmodium falciparum infection.
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  Data: <searchLink fieldCode="AU" term="%22Kirtley+P%22">Kirtley P</searchLink>; Oregon Health and Science University, Vaccine and Gene Therapy Institute, Beaverton, OR, USA.<br /><searchLink fieldCode="AU" term="%22Martinson+T%22">Martinson T</searchLink>; Oregon Health and Science University, Vaccine and Gene Therapy Institute, Beaverton, OR, USA.<br /><searchLink fieldCode="AU" term="%22Donnellan+FR%22">Donnellan FR</searchLink>; Department of Paediatrics and Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Aleshnick+M%22">Aleshnick M</searchLink>; Oregon Health and Science University, Vaccine and Gene Therapy Institute, Beaverton, OR, USA.<br /><searchLink fieldCode="AU" term="%22Nielsen+K%22">Nielsen K</searchLink>; Oregon Health and Science University, Vaccine and Gene Therapy Institute, Beaverton, OR, USA.<br /><searchLink fieldCode="AU" term="%22Mayer+BT%22">Mayer BT</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Borate+B%22">Borate B</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Huang+TJ%22">Huang TJ</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Pipini+D%22">Pipini D</searchLink>; Department of Paediatrics and Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Rigby+CA%22">Rigby CA</searchLink>; Department of Paediatrics and Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Quinkert+D%22">Quinkert D</searchLink>; Department of Paediatrics and Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Silk+SE%22">Silk SE</searchLink>; Department of Paediatrics and Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Minassian+AM%22">Minassian AM</searchLink>; Department of Paediatrics and Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK; NIHR Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22McHugh+K%22">McHugh K</searchLink>; Department of Paediatrics and Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Draper+SJ%22">Draper SJ</searchLink>; Department of Paediatrics and Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK; NIHR Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Wilder+BK%22">Wilder BK</searchLink>; Oregon Health and Science University, Vaccine and Gene Therapy Institute, Beaverton, OR, USA. Electronic address: wilderb@ohsu.edu.
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