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Impact of Fostamatinib on Inflammatory Biomarkers in Hospitalized Patients With COVID-19.

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Title: Impact of Fostamatinib on Inflammatory Biomarkers in Hospitalized Patients With COVID-19.
Authors: Da Cruz RS; Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD.; Critical Care Medicine and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD., Teague HL; Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD.; Critical Care Medicine and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD., Ramos-Benitez MJ; Basic Science Department, Microbiology, Ponce Health Sciences University, Ponce, PR., Malavez-Cajigas SJ; Basic Science Department, Microbiology, Ponce Health Sciences University, Ponce, PR., Williams T; Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD.; Critical Care Medicine and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD., Miao R; Office of Biostatistics Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.; Department of Mathematical Sciences, The University of Texas at Dallas, Richardson, TX., Tian X; Office of Biostatistics Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD., Lin G; Office of Biostatistics Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD., Busse LW; Division of Pulmonary Allergy, Critical Care and Sleep Medicine, Emory University, Atlanta, GA., Khan A; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Oregon Health Sciences University, Portland, OR., Moskowitz A; Division of Critical Care, Montefiore Medical Center, The Bronx, NY., Hager DN; Department of Medicine, Johns Hopkins University, Baltimore, MD., Rice TW; Division of Allergy Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN.; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN., Ginde AA; Department of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO., Iovine NM; Division of Infectious Diseases and Global Medicine, Department of Medicine, University of Florida Health, Gainesville, FL., Chen P; Women's Guild Lung Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA., Safdar B; Department of Emergency Medicine, Yale School of Medicine, New Haven, CT., Gibbs KW; Department of Medicine, Wake Forest School of Medicine, Winston-Salem, NC., Javaheri A; Department of Medicine, Washington University, Saint Louis, MO., de Wit M; Department of Medicine, Virginia Commonwealth University, Richmond, VA., Harkins M; Department of Internal Medicine, University of New Mexico, Albuquerque, NM., Hudock K; Department of Medicine, University of Cincinnati, Cincinnati, OH., Merck LH; Division of Infectious Diseases and Global Medicine, Department of Medicine, University of Florida Health, Gainesville, FL.; Department of Medicine, Virginia Commonwealth University, Richmond, VA., Barksdale A; Department of Emergency Medicine, University of Nebraska Medical Center, Omaha, NE., Sturek JM; Department of Medicine, University of Virginia, Charlottesville, VA., Schrager H; Department of Medicine, Tufts School of Medicine, Newton-Wellesley Hospital, Newton, MA., Shapiro NI; Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA., Lanspa M; Department of Medicine, Intermountain Medical Center, Murray, UT., Harris E; Department of Medicine, University of Utah Health Sciences, Salt Lake City, UT., Sellers S; Department of Medicine, University of North Carolina, Chapel Hill, NC., Goodwin AJ; Department of Medicine, Medical University of South Carolina, Charleston, SC., Tidswell MA; Department of Medicine, Baystate Health, Springfield, MA., Filbin MR; Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA., Shotwell MS; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN., Semler MW; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN., Self WH; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN.; Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN., Collins SP; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN.; Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN.; Veterans Affairs Tennessee Valley Healthcare System, Geriatric Research, Education and Clinical Center, Nashville, TN., Strich JR; Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD.; Critical Care Medicine and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
Corporate Authors: Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV-4) Host Tissue Investigators
Source: Critical care explorations [Crit Care Explor] 2026 Jun 23; Vol. 8 (7), pp. e1405. Date of Electronic Publication: 2026 Jun 23 (Print Publication: 2026).
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III
Journal Info: Publisher: Wolters Kluwer Health Country of Publication: United States NLM ID: 101746347 Publication Model: eCollection Cited Medium: Internet ISSN: 2639-8028 (Electronic) Linking ISSN: 26398028 NLM ISO Abbreviation: Crit Care Explor Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Impact of Fostamatinib on Inflammatory Biomarkers in Hospitalized Patients With COVID-19.
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