Comparative 10-year performance of mammography artificial intelligence, polygenic, and clinical breast cancer risk models in the Kaiser Permanente Research Bank.

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Title: Comparative 10-year performance of mammography artificial intelligence, polygenic, and clinical breast cancer risk models in the Kaiser Permanente Research Bank.
Authors: Arasu VA; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States.; Department of Radiology, Kaiser Permanente Northern California, Vallejo, CA, United States., Gadgil T; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States., Rothstein JH; Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, TX, United States.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Alexeeff SE; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States., Achacoso NS; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States., Bhattacharya A; Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, TX, United States.; Institute for Data Science in Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, United States., Cord JB; Department of Radiology, Southern California Permanente Medical Group, Anaheim, CA, United States., Esserman LJ; Department of Surgery, University of California, San Francisco, San Francisco, CA, United States., Galbraith W; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States., Gerstley LD; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States., Head ST; Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, TX, United States., Hylton NM; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States., Kushi LH; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States., Lee C; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, United States., Leimpeter AD; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States., Lewis DA; Department of Medical Imaging Technology and Informatics, Southern California Permanente Medical Group, Pasadena, CA, United States., Liu V; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States., Marafino BJ; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States., Margolies LR; Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Navarro DA; Department of Nuclear Medicine, The Permanente Medical Group, Oakland, CA, United States., Pu A; KP Information Technology, Kaiser Foundation Health Plan Inc. and Kaiser Foundation Hospitals, Pasadena, CA, United States., Sakoda LC; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States., Shan J; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States., Shieh Y; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, United States.; Department of Medicine, Weill Cornell Medicine, New York, NY, United States., Sistig A; Department of Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Smith Gueye CL; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States., Veer LV; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA, United States., Villaseñor M; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States., Westley M; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States., Wisner DJ; Department of Radiology, Kaiser Permanente Northern California, San Rafael, CA, United States., Tice JA; Department of Medicine, University of California, San Francisco, San Francisco, CA, United States., Shen L; Department of Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Habel LA; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States., Sieh W; Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, TX, United States.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Source: Journal of the National Cancer Institute [J Natl Cancer Inst] 2026 Jun 23. Date of Electronic Publication: 2026 Jun 23.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 7503089 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2105 (Electronic) Linking ISSN: 00278874 NLM ISO Abbreviation: J Natl Cancer Inst Subsets: MEDLINE
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Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States.<br /><searchLink fieldCode="AU" term="%22Bhattacharya+A%22">Bhattacharya A</searchLink>; Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, TX, United States.; Institute for Data Science in Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, United States.<br /><searchLink fieldCode="AU" term="%22Cord+JB%22">Cord JB</searchLink>; Department of Radiology, Southern California Permanente Medical Group, Anaheim, CA, United States.<br /><searchLink fieldCode="AU" term="%22Esserman+LJ%22">Esserman LJ</searchLink>; Department of Surgery, University of California, San Francisco, San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Galbraith+W%22">Galbraith W</searchLink>; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States.<br /><searchLink fieldCode="AU" term="%22Gerstley+LD%22">Gerstley LD</searchLink>; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States.<br /><searchLink fieldCode="AU" term="%22Head+ST%22">Head ST</searchLink>; Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, TX, United States.<br /><searchLink fieldCode="AU" term="%22Hylton+NM%22">Hylton NM</searchLink>; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Kushi+LH%22">Kushi LH</searchLink>; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States.<br /><searchLink fieldCode="AU" term="%22Lee+C%22">Lee C</searchLink>; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Leimpeter+AD%22">Leimpeter AD</searchLink>; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States.<br /><searchLink fieldCode="AU" term="%22Lewis+DA%22">Lewis DA</searchLink>; Department of Medical Imaging Technology and Informatics, Southern California Permanente Medical Group, Pasadena, CA, United States.<br /><searchLink fieldCode="AU" term="%22Liu+V%22">Liu V</searchLink>; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States.<br /><searchLink fieldCode="AU" term="%22Marafino+BJ%22">Marafino BJ</searchLink>; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States.<br /><searchLink fieldCode="AU" term="%22Margolies+LR%22">Margolies LR</searchLink>; Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Navarro+DA%22">Navarro DA</searchLink>; Department of Nuclear Medicine, The Permanente Medical Group, Oakland, CA, United States.<br /><searchLink fieldCode="AU" term="%22Pu+A%22">Pu A</searchLink>; KP Information Technology, Kaiser Foundation Health Plan Inc. and Kaiser Foundation Hospitals, Pasadena, CA, United States.<br /><searchLink fieldCode="AU" term="%22Sakoda+LC%22">Sakoda LC</searchLink>; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States.<br /><searchLink fieldCode="AU" term="%22Shan+J%22">Shan J</searchLink>; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States.<br /><searchLink fieldCode="AU" term="%22Shieh+Y%22">Shieh Y</searchLink>; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, United States.; Department of Medicine, Weill Cornell Medicine, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Sistig+A%22">Sistig A</searchLink>; Department of Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Smith+Gueye+CL%22">Smith Gueye CL</searchLink>; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States.<br /><searchLink fieldCode="AU" term="%22Veer+LV%22">Veer LV</searchLink>; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Villaseñor+M%22">Villaseñor M</searchLink>; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States.<br /><searchLink fieldCode="AU" term="%22Westley+M%22">Westley M</searchLink>; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States.<br /><searchLink fieldCode="AU" term="%22Wisner+DJ%22">Wisner DJ</searchLink>; Department of Radiology, Kaiser Permanente Northern California, San Rafael, CA, United States.<br /><searchLink fieldCode="AU" term="%22Tice+JA%22">Tice JA</searchLink>; Department of Medicine, University of California, San Francisco, San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Shen+L%22">Shen L</searchLink>; Department of Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Habel+LA%22">Habel LA</searchLink>; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States.<br /><searchLink fieldCode="AU" term="%22Sieh+W%22">Sieh W</searchLink>; Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, TX, United States.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
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