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Leaflet Modification to Mitigate Coronary Obstruction Risk During TAVR: Results From the LOFTER-TAVR Registry.

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Title: Leaflet Modification to Mitigate Coronary Obstruction Risk During TAVR: Results From the LOFTER-TAVR Registry.
Authors: Occhipinti G; Institut Clínic Cardiovascular, Clínic Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain. Electronic address: https://twitter.com/drgocchipinti., Laudani C; Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico 'Rodolico-San Marco,' University of Catania, Catania, Italy; Division of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA. Electronic address: https://twitter.com/LaudaniClaudio., Jabri A; Center for Structural Heart Disease, Henry Ford Hospital, Detroit, Michigan, USA., Pensotti F; Cardiology Department, University Clinic Hospital, Valladolid, Spain., Leone PP; Montefiore-Einstein Center for Heart and Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA; Interventional Cardiology, White Plains Hospital, White Plains, New York, USA., Khokhar AA; The Heart Center, Rigshospitalet, Copenhagen, Denmark., Genereux P; Gagnon Cardiovascular Institute, Morristown Medical Center, Morristown, New Jersey, USA., Beneduce A; Heart Valve Center, IRCCS San Raffaele Scientific Institute, Milan, Italy., Wongpraparut N; Division of Cardiology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Mangieri A; Humanitas Research Hospital IRCCS, Milan, Italy., Serra V; Cardiology Department, Hospital Universitario Vall d'Hebron, Barcelona, Spain., Nombela-Franco L; Cardiovascular Institute, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain., Sanchez JS; Servicio de Cardiología, Hospital Universitari i Politècnic La Fe, Valencia, Spain; Centro de Investigación Biomédica en Red Enfermedades Cardiovaculares, Madrid, Spain., Asmarats L; Department of Cardiology, Hospital de la Santa Creu i Sant Pau, Institut de Recerca Sant Pau, Barcelona, Spain., Teles RC; Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide and Comprehensive Health Research Center, Nova Medical School, Lisbon, Portugal., Chandavimol M; Department of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand., Romaguera R; Department of Cardiology, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain; Bioheart Group, Cardiovascular, Respiratory and Systemic Diseases and Cellular Aging Program, Institut d'Investigació Biomèdica de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain; Department of Clinical Sciences, School of Medicine, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain., Akodad M; Ramsay Générale de Santé, Institut Cardiovasculaire Paris Sud, Massy, France., Cuisset T; Department of Cardiology, CHU Timone, Marseille, France; C2VN, Thomas University, INSERM, INRA, Marseille, France., Tayal R; Valley Health System, Paramus, New Jersey, USA., Algethami AR; King Abdulaziz Cardiac Center, Ministry of the National Guard Health Affairs, Riyadh, Saudi Arabia., Díaz JF; Hospital Universitario Virgen del Rocío, Sevilla, Spain., Laffond A; Complejo Asistencial Universitario de Salamanca, Salamanca, Spain., Martin P; Hospital Universitario de Gran Canaria, Las Palmas de Gran Canaria, Spain., Perez L; Hospital Guillermo Grant Benavente, Concepción, Chile., Ruiz-Quevedo V; Hospital Universitario de Navarra, Pamplona, Spain., Sarno G; Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden., Vázquez Álvarez ME; Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, Madrid, Spain., Assafin M; Montefiore-Einstein Center for Heart and Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA; Interventional Cardiology, White Plains Hospital, White Plains, New York, USA., García-Gómez M; Cardiology Department, University Clinic Hospital, Valladolid, Spain., Ruberti A; Department of Cardiology, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain., Sanchis L; Institut Clínic Cardiovascular, Clínic Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain., Freixa X; Institut Clínic Cardiovascular, Clínic Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain., Maisano F; Heart Valve Center, IRCCS San Raffaele Scientific Institute, Milan, Italy., Buzzatti N; Heart Valve Center, IRCCS San Raffaele Scientific Institute, Milan, Italy., Giustino G; Gagnon Cardiovascular Institute, Morristown Medical Center, Morristown, New Jersey, USA., De Backer O; The Heart Center, Rigshospitalet, Copenhagen, Denmark; Institute of Clinical Medicine, University of Copenhagen, Denmark., Latib A; Montefiore-Einstein Center for Heart and Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA; Interventional Cardiology, White Plains Hospital, White Plains, New York, USA., Amat-Santos IJ; Cardiology Department, University Clinic Hospital, Valladolid, Spain; Centro de Investigación Biomédica en Red Enfermedades Cardiovaculares, Madrid, Spain., Villablanca PA; Center for Structural Heart Disease, Henry Ford Hospital, Detroit, Michigan, USA., Regueiro A; Institut Clínic Cardiovascular, Clínic Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain. Electronic address: aregueir@clinic.cat.
Source: JACC. Cardiovascular interventions [JACC Cardiovasc Interv] 2026 Jun 22; Vol. 19 (12), pp. 1639-1649.
Publication Type: Journal Article; Multicenter Study; Observational Study
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101467004 Publication Model: Print Cited Medium: Internet ISSN: 1876-7605 (Electronic) Linking ISSN: 19368798 NLM ISO Abbreviation: JACC Cardiovasc Interv Subsets: MEDLINE
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  Data: Leaflet Modification to Mitigate Coronary Obstruction Risk During TAVR: Results From the LOFTER-TAVR Registry.
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  Data: <searchLink fieldCode="AU" term="%22Occhipinti+G%22">Occhipinti G</searchLink>; Institut Clínic Cardiovascular, Clínic Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain. Electronic address: https://twitter.com/drgocchipinti.<br /><searchLink fieldCode="AU" term="%22Laudani+C%22">Laudani C</searchLink>; Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico 'Rodolico-San Marco,' University of Catania, Catania, Italy; Division of Cardiology, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA. 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Ramsay Générale de Santé, Institut Cardiovasculaire Paris Sud, Massy, France.<br /><searchLink fieldCode="AU" term="%22Cuisset+T%22">Cuisset T</searchLink>; Department of Cardiology, CHU Timone, Marseille, France; C2VN, Thomas University, INSERM, INRA, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Tayal+R%22">Tayal R</searchLink>; Valley Health System, Paramus, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Algethami+AR%22">Algethami AR</searchLink>; King Abdulaziz Cardiac Center, Ministry of the National Guard Health Affairs, Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Díaz+JF%22">Díaz JF</searchLink>; Hospital Universitario Virgen del Rocío, Sevilla, Spain.<br /><searchLink fieldCode="AU" term="%22Laffond+A%22">Laffond A</searchLink>; Complejo Asistencial Universitario de Salamanca, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Martin+P%22">Martin P</searchLink>; Hospital Universitario de Gran Canaria, Las Palmas de Gran Canaria, Spain.<br /><searchLink fieldCode="AU" term="%22Perez+L%22">Perez L</searchLink>; Hospital Guillermo Grant Benavente, Concepción, Chile.<br /><searchLink fieldCode="AU" term="%22Ruiz-Quevedo+V%22">Ruiz-Quevedo V</searchLink>; Hospital Universitario de Navarra, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Sarno+G%22">Sarno G</searchLink>; Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Vázquez+Álvarez+ME%22">Vázquez Álvarez ME</searchLink>; Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Assafin+M%22">Assafin M</searchLink>; Montefiore-Einstein Center for Heart and Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA; Interventional Cardiology, White Plains Hospital, White Plains, New York, USA.<br /><searchLink fieldCode="AU" term="%22García-Gómez+M%22">García-Gómez M</searchLink>; Cardiology Department, University Clinic Hospital, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Ruberti+A%22">Ruberti A</searchLink>; Department of Cardiology, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Sanchis+L%22">Sanchis L</searchLink>; Institut Clínic Cardiovascular, Clínic Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Freixa+X%22">Freixa X</searchLink>; Institut Clínic Cardiovascular, Clínic Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Maisano+F%22">Maisano F</searchLink>; Heart Valve Center, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Buzzatti+N%22">Buzzatti N</searchLink>; Heart Valve Center, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Giustino+G%22">Giustino G</searchLink>; Gagnon Cardiovascular Institute, Morristown Medical Center, Morristown, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22De+Backer+O%22">De Backer O</searchLink>; The Heart Center, Rigshospitalet, Copenhagen, Denmark; Institute of Clinical Medicine, University of Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Latib+A%22">Latib A</searchLink>; Montefiore-Einstein Center for Heart and Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA; Interventional Cardiology, White Plains Hospital, White Plains, New York, USA.<br /><searchLink fieldCode="AU" term="%22Amat-Santos+IJ%22">Amat-Santos IJ</searchLink>; Cardiology Department, University Clinic Hospital, Valladolid, Spain; Centro de Investigación Biomédica en Red Enfermedades Cardiovaculares, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Villablanca+PA%22">Villablanca PA</searchLink>; Center for Structural Heart Disease, Henry Ford Hospital, Detroit, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Regueiro+A%22">Regueiro A</searchLink>; Institut Clínic Cardiovascular, Clínic Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain. Electronic address: aregueir@clinic.cat.
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