View in EDS

A Humanized Knock-in Mouse Model of the PSEN1 V97L Mutation from a Major Chinese Alzheimer's Disease Pedigree Reveals Early Neuroinflammation.

Saved in:
Bibliographic Details
Title: A Humanized Knock-in Mouse Model of the PSEN1 V97L Mutation from a Major Chinese Alzheimer's Disease Pedigree Reveals Early Neuroinflammation.
Authors: Dai L; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China., Lv S; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China., Guo H; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China., Li Z; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China., Li J; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China., Wang Y; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China., Du M; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China., Wu D; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China., Ma K; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China., Wu N; Laboratory Animal Resource Center, Capital Medical University, Beijing, 100069, China., Zhang J; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China. zhangjing2016@ccmu.edu.cn., Chen B; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China. baianchen@ccmu.edu.cn.; Center of Alzheimer's Disease, Beijing Institute of Brain Disorders, Capital Medical University, Beijing, 100069, China. baianchen@ccmu.edu.cn.; Laboratory Animal Resource Center, Capital Medical University, Beijing, 100069, China. baianchen@ccmu.edu.cn.
Source: Neuroscience bulletin [Neurosci Bull] 2026 Jun 23. Date of Electronic Publication: 2026 Jun 23.
Publication Type: Journal Article
Journal Info: Publisher: Springer Singapore Country of Publication: Singapore NLM ID: 101256850 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1995-8218 (Electronic) Linking ISSN: 19958218 NLM ISO Abbreviation: Neurosci Bull Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42334726
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: A Humanized Knock-in Mouse Model of the PSEN1 V97L Mutation from a Major Chinese Alzheimer's Disease Pedigree Reveals Early Neuroinflammation.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Dai+L%22">Dai L</searchLink>; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.<br /><searchLink fieldCode="AU" term="%22Lv+S%22">Lv S</searchLink>; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.<br /><searchLink fieldCode="AU" term="%22Guo+H%22">Guo H</searchLink>; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.<br /><searchLink fieldCode="AU" term="%22Du+M%22">Du M</searchLink>; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.<br /><searchLink fieldCode="AU" term="%22Wu+D%22">Wu D</searchLink>; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.<br /><searchLink fieldCode="AU" term="%22Ma+K%22">Ma K</searchLink>; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.<br /><searchLink fieldCode="AU" term="%22Wu+N%22">Wu N</searchLink>; Laboratory Animal Resource Center, Capital Medical University, Beijing, 100069, China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China. zhangjing2016@ccmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Chen+B%22">Chen B</searchLink>; Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China. baianchen@ccmu.edu.cn.; Center of Alzheimer's Disease, Beijing Institute of Brain Disorders, Capital Medical University, Beijing, 100069, China. baianchen@ccmu.edu.cn.; Laboratory Animal Resource Center, Capital Medical University, Beijing, 100069, China. baianchen@ccmu.edu.cn.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101256850%22">Neuroscience bulletin</searchLink> [Neurosci Bull] 2026 Jun 23. <i>Date of Electronic Publication: </i>2026 Jun 23.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Singapore%22">Springer Singapore </searchLink><i>Country of Publication: </i>Singapore <i>NLM ID: </i>101256850 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1995-8218 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219958218%22">19958218 </searchLink><i>NLM ISO Abbreviation: </i>Neurosci Bull <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42334726
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s12264-026-01656-9
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: A Humanized Knock-in Mouse Model of the PSEN1 V97L Mutation from a Major Chinese Alzheimer's Disease Pedigree Reveals Early Neuroinflammation.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Dai L
      – PersonEntity:
          Name:
            NameFull: Lv S
      – PersonEntity:
          Name:
            NameFull: Guo H
      – PersonEntity:
          Name:
            NameFull: Li Z
      – PersonEntity:
          Name:
            NameFull: Li J
      – PersonEntity:
          Name:
            NameFull: Wang Y
      – PersonEntity:
          Name:
            NameFull: Du M
      – PersonEntity:
          Name:
            NameFull: Wu D
      – PersonEntity:
          Name:
            NameFull: Ma K
      – PersonEntity:
          Name:
            NameFull: Wu N
      – PersonEntity:
          Name:
            NameFull: Zhang J
      – PersonEntity:
          Name:
            NameFull: Chen B
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 23
              M: 06
              Text: 2026 Jun 23
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1995-8218
          Titles:
            – TitleFull: Neuroscience bulletin
              Type: main
ResultId 1