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Dupilumab treatment restores skin nerve fibre density in patients with moderate-to-severe atopic dermatitis: results from DIFFERENSTAD, an open-label exploratory study.

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Title: Dupilumab treatment restores skin nerve fibre density in patients with moderate-to-severe atopic dermatitis: results from DIFFERENSTAD, an open-label exploratory study.
Authors: Agelopoulos K; Department of Dermatology and Center for Chronic Pruritus, University Hospital Münster, Münster, Germany., Nattkemper L; Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery and Miami Itch Center, University of Miami, Miami, FL, USA., Witte F; Department of Dermatology and Center for Chronic Pruritus, University Hospital Münster, Münster, Germany., Zeidler C; Department of Dermatology and Center for Chronic Pruritus, University Hospital Münster, Münster, Germany., Bagel J; Eczema Treatment Center of New Jersey, East Windsor, NJ, USA., Praestgaard AH; Sanofi, Cambridge, MA, USA., Bologna G; Ividata Life Science (contracted for Sanofi), Levallois-Perret, France., Mack M; Sanofi, Cambridge, MA, USA., Zahn J; Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA., Zhang A; Sanofi, Cambridge, MA, USA., Yosipovitch G; Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery and Miami Itch Center, University of Miami, Miami, FL, USA., Ständer S; Department of Dermatology and Center for Chronic Pruritus, University Hospital Münster, Münster, Germany.
Source: The British journal of dermatology [Br J Dermatol] 2026 Jun 23. Date of Electronic Publication: 2026 Jun 23.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0004041 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2133 (Electronic) Linking ISSN: 00070963 NLM ISO Abbreviation: Br J Dermatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dupilumab treatment restores skin nerve fibre density in patients with moderate-to-severe atopic dermatitis: results from DIFFERENSTAD, an open-label exploratory study.
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  Data: <searchLink fieldCode="AU" term="%22Agelopoulos+K%22">Agelopoulos K</searchLink>; Department of Dermatology and Center for Chronic Pruritus, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Nattkemper+L%22">Nattkemper L</searchLink>; Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery and Miami Itch Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Witte+F%22">Witte F</searchLink>; Department of Dermatology and Center for Chronic Pruritus, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Zeidler+C%22">Zeidler C</searchLink>; Department of Dermatology and Center for Chronic Pruritus, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Bagel+J%22">Bagel J</searchLink>; Eczema Treatment Center of New Jersey, East Windsor, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Praestgaard+AH%22">Praestgaard AH</searchLink>; Sanofi, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bologna+G%22">Bologna G</searchLink>; Ividata Life Science (contracted for Sanofi), Levallois-Perret, France.<br /><searchLink fieldCode="AU" term="%22Mack+M%22">Mack M</searchLink>; Sanofi, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zahn+J%22">Zahn J</searchLink>; Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+A%22">Zhang A</searchLink>; Sanofi, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Yosipovitch+G%22">Yosipovitch G</searchLink>; Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery and Miami Itch Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Ständer+S%22">Ständer S</searchLink>; Department of Dermatology and Center for Chronic Pruritus, University Hospital Münster, Münster, Germany.
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  Data: <searchLink fieldCode="JN" term="%220004041%22">The British journal of dermatology</searchLink> [Br J Dermatol] 2026 Jun 23. <i>Date of Electronic Publication: </i>2026 Jun 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0004041 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1365-2133 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200070963%22">00070963 </searchLink><i>NLM ISO Abbreviation: </i>Br J Dermatol <i>Subsets: </i>MEDLINE
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        Value: 10.1093/bjd/ljag256
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              Text: 2026 Jun 23
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