Identifying potential drug targets for physical and cognitive frailty: an integrative analysis of CHARLS cohort, mendelian randomization, and gene colocalization.
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| Title: | Identifying potential drug targets for physical and cognitive frailty: an integrative analysis of CHARLS cohort, mendelian randomization, and gene colocalization. |
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| Authors: | Liu W; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China., Zhao J; Department of Spine Surgery, The Second Qilu Hospital of Shandong University, Jinan, Shandong, China., Liu ZQ; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China., Sun XD; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China., Dong YY; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China., Meng YJ; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China., Jiang WD; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China., Liu Z; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China. liuzhen1204@163.com. |
| Source: | Biogerontology [Biogerontology] 2026 Jun 23; Vol. 27 (4). Date of Electronic Publication: 2026 Jun 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Kluwer Academic Country of Publication: Netherlands NLM ID: 100930043 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-6768 (Electronic) Linking ISSN: 13895729 NLM ISO Abbreviation: Biogerontology Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42337223 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Identifying potential drug targets for physical and cognitive frailty: an integrative analysis of CHARLS cohort, mendelian randomization, and gene colocalization. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Liu+W%22">Liu W</searchLink>; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China.<br /><searchLink fieldCode="AU" term="%22Zhao+J%22">Zhao J</searchLink>; Department of Spine Surgery, The Second Qilu Hospital of Shandong University, Jinan, Shandong, China.<br /><searchLink fieldCode="AU" term="%22Liu+ZQ%22">Liu ZQ</searchLink>; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China.<br /><searchLink fieldCode="AU" term="%22Sun+XD%22">Sun XD</searchLink>; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China.<br /><searchLink fieldCode="AU" term="%22Dong+YY%22">Dong YY</searchLink>; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China.<br /><searchLink fieldCode="AU" term="%22Meng+YJ%22">Meng YJ</searchLink>; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China.<br /><searchLink fieldCode="AU" term="%22Jiang+WD%22">Jiang WD</searchLink>; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China. liuzhen1204@163.com. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22100930043%22">Biogerontology</searchLink> [Biogerontology] 2026 Jun 23; Vol. 27 (4). <i>Date of Electronic Publication: </i>2026 Jun 23. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Kluwer+Academic%22">Kluwer Academic </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>100930043 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-6768 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213895729%22">13895729 </searchLink><i>NLM ISO Abbreviation: </i>Biogerontology <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42337223 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10522-026-10466-5 Languages: – Code: eng Text: English Titles: – TitleFull: Identifying potential drug targets for physical and cognitive frailty: an integrative analysis of CHARLS cohort, mendelian randomization, and gene colocalization. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Liu W – PersonEntity: Name: NameFull: Zhao J – PersonEntity: Name: NameFull: Liu ZQ – PersonEntity: Name: NameFull: Sun XD – PersonEntity: Name: NameFull: Dong YY – PersonEntity: Name: NameFull: Meng YJ – PersonEntity: Name: NameFull: Jiang WD – PersonEntity: Name: NameFull: Liu Z IsPartOfRelationships: – BibEntity: Dates: – D: 23 M: 06 Text: 2026 Jun 23 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1573-6768 Numbering: – Type: volume Value: 27 – Type: issue Value: 4 Titles: – TitleFull: Biogerontology Type: main |
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