Autoantigen-loaded Polymeric Microparticles associate with B cells and promote tolerogenic antigen presentation in a mouse model of experimental autoimmune encephalomyelitis.
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| Title: | Autoantigen-loaded Polymeric Microparticles associate with B cells and promote tolerogenic antigen presentation in a mouse model of experimental autoimmune encephalomyelitis. |
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| Authors: | Lukesh NR; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA., Barbery BG; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA., Clark KA; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA., Ontiveros-Padilla L; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA., Ehrenzeller SA; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA., Woodring RN; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA., Mendell SE; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA., Middleton DD; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA., Islam MJ; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA., Pena ES; Department of Biomedical Engineering, NC State/UNC, Chapel Hill, NC, USA., Hendy DA; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA., Simpson SR; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA., Graham-Gurysh EG; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA., Lopez AM; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA., Murphy CT; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA., Williamson GL; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA., Ly SA; Department of Biomedical Engineering, NC State/UNC, Chapel Hill, NC, USA., Shilling KE; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA., Landoni E; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA., Stiepel RT; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA., Sherwin D; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Genetics, School of Medicine, UNC, Chapel Hill, NC, USA., Ke Q; Department of Microbiology and Immunology, School of Medicine, UNC, Chapel Hill, NC, USA., Savoldo B; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Pediatrics, University of North Carolina, Chapel Hill, NC, USA., Dotti G; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, School of Medicine, UNC, Chapel Hill, NC, USA., Pylayeva-Gupta Y; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Genetics, School of Medicine, UNC, Chapel Hill, NC, USA., Tisch RM; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, School of Medicine, UNC, Chapel Hill, NC, USA., Bachelder EM; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA., Ainslie KM; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA. ainsliek@email.unc.edu.; Department of Biomedical Engineering, NC State/UNC, Chapel Hill, NC, USA. ainsliek@email.unc.edu.; Department of Microbiology and Immunology, School of Medicine, UNC, Chapel Hill, NC, USA. ainsliek@email.unc.edu. |
| Source: | Nature communications [Nat Commun] 2026 Jun 23. Date of Electronic Publication: 2026 Jun 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42337240 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Autoantigen-loaded Polymeric Microparticles associate with B cells and promote tolerogenic antigen presentation in a mouse model of experimental autoimmune encephalomyelitis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Lukesh+NR%22">Lukesh NR</searchLink>; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Barbery+BG%22">Barbery BG</searchLink>; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Clark+KA%22">Clark KA</searchLink>; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Ontiveros-Padilla+L%22">Ontiveros-Padilla L</searchLink>; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Ehrenzeller+SA%22">Ehrenzeller SA</searchLink>; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Woodring+RN%22">Woodring RN</searchLink>; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Mendell+SE%22">Mendell SE</searchLink>; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Middleton+DD%22">Middleton DD</searchLink>; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Islam+MJ%22">Islam MJ</searchLink>; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Pena+ES%22">Pena ES</searchLink>; Department of Biomedical Engineering, NC State/UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Hendy+DA%22">Hendy DA</searchLink>; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Simpson+SR%22">Simpson SR</searchLink>; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Graham-Gurysh+EG%22">Graham-Gurysh EG</searchLink>; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Lopez+AM%22">Lopez AM</searchLink>; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Murphy+CT%22">Murphy CT</searchLink>; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Williamson+GL%22">Williamson GL</searchLink>; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Ly+SA%22">Ly SA</searchLink>; Department of Biomedical Engineering, NC State/UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Shilling+KE%22">Shilling KE</searchLink>; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Landoni+E%22">Landoni E</searchLink>; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Stiepel+RT%22">Stiepel RT</searchLink>; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Sherwin+D%22">Sherwin D</searchLink>; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Genetics, School of Medicine, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Ke+Q%22">Ke Q</searchLink>; Department of Microbiology and Immunology, School of Medicine, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Savoldo+B%22">Savoldo B</searchLink>; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Pediatrics, University of North Carolina, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Dotti+G%22">Dotti G</searchLink>; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, School of Medicine, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Pylayeva-Gupta+Y%22">Pylayeva-Gupta Y</searchLink>; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Genetics, School of Medicine, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Tisch+RM%22">Tisch RM</searchLink>; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, School of Medicine, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Bachelder+EM%22">Bachelder EM</searchLink>; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Ainslie+KM%22">Ainslie KM</searchLink>; Division of Pharmacoengineering & Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC, Chapel Hill, NC, USA. ainsliek@email.unc.edu.; Department of Biomedical Engineering, NC State/UNC, Chapel Hill, NC, USA. ainsliek@email.unc.edu.; Department of Microbiology and Immunology, School of Medicine, UNC, Chapel Hill, NC, USA. ainsliek@email.unc.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 Jun 23. <i>Date of Electronic Publication: </i>2026 Jun 23. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. 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| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42337240 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41467-026-74641-5 Languages: – Code: eng Text: English Titles: – TitleFull: Autoantigen-loaded Polymeric Microparticles associate with B cells and promote tolerogenic antigen presentation in a mouse model of experimental autoimmune encephalomyelitis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lukesh NR – PersonEntity: Name: NameFull: Barbery BG – PersonEntity: Name: NameFull: Clark KA – PersonEntity: Name: NameFull: Ontiveros-Padilla L – PersonEntity: Name: NameFull: Ehrenzeller SA – PersonEntity: Name: NameFull: Woodring RN – PersonEntity: Name: NameFull: Mendell SE – PersonEntity: Name: NameFull: Middleton DD – PersonEntity: Name: NameFull: Islam MJ – PersonEntity: Name: NameFull: Pena ES – PersonEntity: Name: NameFull: Hendy DA – PersonEntity: Name: NameFull: Simpson SR – PersonEntity: Name: NameFull: Graham-Gurysh EG – PersonEntity: Name: NameFull: Lopez AM – PersonEntity: Name: NameFull: Murphy CT – PersonEntity: Name: NameFull: Williamson GL – PersonEntity: Name: NameFull: Ly SA – PersonEntity: Name: NameFull: Shilling KE – PersonEntity: Name: NameFull: Landoni E – PersonEntity: Name: NameFull: Stiepel RT – PersonEntity: Name: NameFull: Sherwin D – PersonEntity: Name: NameFull: Ke Q – PersonEntity: Name: NameFull: Savoldo B – PersonEntity: Name: NameFull: Dotti G – PersonEntity: Name: NameFull: Pylayeva-Gupta Y – PersonEntity: Name: NameFull: Tisch RM – PersonEntity: Name: NameFull: Bachelder EM – PersonEntity: Name: NameFull: Ainslie KM IsPartOfRelationships: – BibEntity: Dates: – D: 23 M: 06 Text: 2026 Jun 23 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2041-1723 Titles: – TitleFull: Nature communications Type: main |
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