A comparison of methods for designing hybrid type 2 cluster-randomized trials with continuous effectiveness and implementation endpoints.

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Title: A comparison of methods for designing hybrid type 2 cluster-randomized trials with continuous effectiveness and implementation endpoints.
Authors: Owen MA; Center for Methods in Implementation and Prevention Science, Yale University, New Haven, CT, USA., Li F; Center for Methods in Implementation and Prevention Science, Yale University, New Haven, CT, USA., Liu R; Center for Methods in Implementation and Prevention Science, Yale University, New Haven, CT, USA., Spiegelman D; Center for Methods in Implementation and Prevention Science, Yale University, New Haven, CT, USA.
Source: Statistical methods in medical research [Stat Methods Med Res] 2026 Jul; Vol. 35 (7), pp. 1493-1517. Date of Electronic Publication: 2026 Jun 23.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: SAGE Publications Country of Publication: England NLM ID: 9212457 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-0334 (Electronic) Linking ISSN: 09622802 NLM ISO Abbreviation: Stat Methods Med Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Owen+MA%22">Owen MA</searchLink>; Center for Methods in Implementation and Prevention Science, Yale University, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Li+F%22">Li F</searchLink>; Center for Methods in Implementation and Prevention Science, Yale University, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Liu+R%22">Liu R</searchLink>; Center for Methods in Implementation and Prevention Science, Yale University, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Spiegelman+D%22">Spiegelman D</searchLink>; Center for Methods in Implementation and Prevention Science, Yale University, New Haven, CT, USA.
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  Data: <searchLink fieldCode="JN" term="%229212457%22">Statistical methods in medical research</searchLink> [Stat Methods Med Res] 2026 Jul; Vol. 35 (7), pp. 1493-1517. <i>Date of Electronic Publication: </i>2026 Jun 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22SAGE+Publications%22">SAGE Publications </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9212457 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1477-0334 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209622802%22">09622802 </searchLink><i>NLM ISO Abbreviation: </i>Stat Methods Med Res <i>Subsets: </i>MEDLINE
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        Value: 10.1177/09622802261457277
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        Text: English
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      – TitleFull: A comparison of methods for designing hybrid type 2 cluster-randomized trials with continuous effectiveness and implementation endpoints.
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            NameFull: Li F
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            – D: 01
              M: 07
              Text: 2026 Jul
              Type: published
              Y: 2026
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