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A novel antibody against CD300c ameliorates cognitive deficits and reduces pathology in the late-stage of APP/PS1 mouse model.

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Title: A novel antibody against CD300c ameliorates cognitive deficits and reduces pathology in the late-stage of APP/PS1 mouse model.
Authors: Lee S; CentricsBio, Inc., Seoul, Republic of Korea.; Department of Life Sciences, Ewha Womans University, Seoul, Republic of Korea., Choi BJ; Department of Physiology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea., Park MH; Department of Physiology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea., Park S; CentricsBio, Inc., Seoul, Republic of Korea., Kim J; CentricsBio, Inc., Seoul, Republic of Korea., Jin HK; Department of Laboratory Animal Medicine, College of Veterinary Medicine, Kyungpook National University, Daegu, Republic of Korea., Shim H; Department of Life Sciences, Ewha Womans University, Seoul, Republic of Korea., Jeon JW; CentricsBio, Inc., Seoul, Republic of Korea., Bae JS; Department of Physiology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Source: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2026 Jun 23, pp. 13872877261458360. Date of Electronic Publication: 2026 Jun 23.
Publication Type: Journal Article
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 9814863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8908 (Electronic) Linking ISSN: 13872877 NLM ISO Abbreviation: J Alzheimers Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: A novel antibody against CD300c ameliorates cognitive deficits and reduces pathology in the late-stage of APP/PS1 mouse model.
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  Data: <searchLink fieldCode="AU" term="%22Lee+S%22">Lee S</searchLink>; CentricsBio, Inc., Seoul, Republic of Korea.; Department of Life Sciences, Ewha Womans University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+BJ%22">Choi BJ</searchLink>; Department of Physiology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+MH%22">Park MH</searchLink>; Department of Physiology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+S%22">Park S</searchLink>; CentricsBio, Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; CentricsBio, Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jin+HK%22">Jin HK</searchLink>; Department of Laboratory Animal Medicine, College of Veterinary Medicine, Kyungpook National University, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shim+H%22">Shim H</searchLink>; Department of Life Sciences, Ewha Womans University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jeon+JW%22">Jeon JW</searchLink>; CentricsBio, Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Bae+JS%22">Bae JS</searchLink>; Department of Physiology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
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  Data: <searchLink fieldCode="JN" term="%229814863%22">Journal of Alzheimer's disease : JAD</searchLink> [J Alzheimers Dis] 2026 Jun 23, pp. 13872877261458360. <i>Date of Electronic Publication: </i>2026 Jun 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22SAGE+Publications%22">SAGE Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9814863 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1875-8908 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213872877%22">13872877 </searchLink><i>NLM ISO Abbreviation: </i>J Alzheimers Dis <i>Subsets: </i>MEDLINE
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        Value: 10.1177/13872877261458360
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        Text: English
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      – TitleFull: A novel antibody against CD300c ameliorates cognitive deficits and reduces pathology in the late-stage of APP/PS1 mouse model.
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            NameFull: Lee S
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            – D: 23
              M: 06
              Text: 2026 Jun 23
              Type: published
              Y: 2026
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