Real-world, multi-omics validation of the clinical relevance of molecular taxonomy for myelodysplastic syndromes (MDS).

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Title: Real-world, multi-omics validation of the clinical relevance of molecular taxonomy for myelodysplastic syndromes (MDS).
Authors: Maggioni G; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Todisco G; IRCCS Humanitas Research Hospital Rozzano Milan Italy.; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy., Sauta E; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Lanino L; Hematology Section, Department of Internal Medicine Yale School of Medicine New Haven USA., Ball S; Vanderbilt Ingram Cancer Center and Vanderbilt University School of Medicine Nashville Tennessee USA., Bewersdorf JP; Hematology Section, Department of Internal Medicine Yale School of Medicine New Haven USA., Kewan T; Hematology Section, Department of Internal Medicine Yale School of Medicine New Haven USA., Al Ali NH; Department of Malignant Hematology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA., Fenaux P; Hôpital Saint-Louis Université Paris Cité Paris France., Platzbecker U; Universitätsklinikum Carl Gustav Carus Dresden Germany., Santini V; University of Florence Florence Italy., Xie Z; Department of Malignant Hematology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA., Brunner AM; Leukemia Program, Massachusetts General Hospital Cancer Center Harvard Medical School Boston Massachusetts USA., Kuykendall AT; Department of Malignant Hematology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA., Bennett JM; University of Rochester Medical Center Rochester New York USA., Buckstein R; Odette Cancer Centre Sunnybrook Health Sciences Centre Toronto Ontario Canada., Bejar R; University of California San Diego La Jolla California USA., Carraway HE; Leukemia Program, Taussig Cancer Institute Cleveland Clinic Cleveland Ohio USA., DeZern AE; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University Baltimore Maryland USA., Griffiths EA; Roswell Park Comprehensive Cancer Center Buffalo New York USA., Halene S; Hematology Section, Department of Internal Medicine Yale School of Medicine New Haven USA., Hasserjian RP; Massachusetts General Hospital Boston Massachusetts USA., List AF; Precision BioSciences Durham North Carolina USA., Loghavi S; Department of Hematopathology The University of Texas MD Anderson Cancer Center Houston Texas USA., Odenike O; University of Chicago Medicine and University of Chicago Comprehensive Cancer Center Chicago Illinois USA., Padron E; Department of Malignant Hematology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA., Patnaik MM; Department of Internal Medicine, Division of Hematology Mayo Clinic Rochester Minnesota USA., Roboz GJ; New York-Presbyterian/Weill Cornell Medicine New York New York USA., Stahl M; Hematology Section, Department of Internal Medicine Yale School of Medicine New Haven USA., Sekeres MA; Sylvester Comprehensive Cancer Center University of Miami Miami Florida USA., Steensma DP; Ajax Therapeutics Cambridge Massachusetts USA., Savona MR; Vanderbilt Ingram Cancer Center and Vanderbilt University School of Medicine Nashville Tennessee USA., Taylor J; Sylvester Comprehensive Cancer Center University of Miami Miami Florida USA., Xu ML; Department of Pathology & Laboratory Medicine Yale School of Medicine New Haven Connecticut USA., Sallman DA; Department of Malignant Hematology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA., Nimer SD; Sylvester Comprehensive Cancer Center University of Miami Miami Florida USA., Hourigan CS; Virginia Tech FBRI Cancer Research Center Washington District of Columbia USA., Wei AH; Department of Haematology Peter MacCallum Cancer Centre, Melbourne Victoria Australia., Campagna A; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Ubezio M; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Riva E; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Ventura D; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Pinocchio N; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Zampini M; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Buizza A; IRCCS Humanitas Research Hospital Rozzano Milan Italy.; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy., Russo A; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Pesce F; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy., D'Amico S; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Asti G; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Delleani M; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Travaglino E; IRCCS Policlinico San Matteo Pavia Italy., Tentori CA; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Ferrari I; IRCCS Humanitas Research Hospital Rozzano Milan Italy.; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy., Crespi A; IRCCS Humanitas Research Hospital Rozzano Milan Italy.; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy., Figini G; IRCCS Humanitas Research Hospital Rozzano Milan Italy.; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy., Di Matteo M; IRCCS Humanitas Research Hospital Rozzano Milan Italy.; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy., Brindisi M; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Manes N; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Milanesi C; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Crisafulli L; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Ficara F; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Castellani G; Department of Medical and Surgical Sciences-DIMEC University of Bologna Bologna Italy., Borate UM; Department of Internal Medicine, Division of Hematology The Ohio State University Columbus Ohio USA., Efficace F; Italian Group for Adult Haematologic Diseases (GIMEMA) Rome Italy., Gore SD; Division of Cancer Prevention National Cancer Institute Rockville Maryland USA., Kim TK; Vanderbilt Ingram Cancer Center and Vanderbilt University School of Medicine Nashville Tennessee USA., Diez-Campelo M; Department of Hematology Hospital Universitario de Salamanca Salamanca Spain., van de Loosdrecht AA; Department of Hematology VU University Medical Center-Cancer Center Amsterdam Netherlands., Daver N; Department of Leukemia The University of Texas MD Anderson Cancer Center Houston Texas USA., Rozman M; Hospital Clínic Barcelona Barcelona Spain., Orfao A; Department of Hematology Hospital Universitario de Salamanca Salamanca Spain., Wang SA; Department of Hematopathology The University of Texas MD Anderson Cancer Center Houston Texas USA., Foucar K; University of New Mexico Albuquerque New Mexico USA., Iastrebner M; Sanatorio Sagrado Corazón Buenos Aires Argentina., Scheinberg P; Hospital A Beneficência Portuguesa de São Paulo Sao Paulo Brazil., Miyazaki Y; Atomic Bomb Disease Institute Nagasaki University Nagasaki Japan., Madanat YF; Division of Hematology and Oncology UT Southwestern Dallas Texas USA., Al-Kali A; Department of Internal Medicine, Division of Hematology Mayo Clinic Rochester Minnesota USA., Mittelmann M; Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine Tel Aviv University Tel-Aviv Israel., Cluzeau T; Nice University Hospital Nice France., Ades L; Hôpital Saint-Louis Université Paris Cité Paris France., Germing U; Department of Hematology, Oncology, and Clinical Immunology Heinrich-Heine-University Düsseldorf Germany., Garcia-Manero G; Department of Leukemia The University of Texas MD Anderson Cancer Center Houston Texas USA., Kordasti S; Department of Haematology Guy's Hospital & Comprehensive Cancer Centre, King's College London UK., Haferlach T; MLL Munich Leukemia Laboratory Munich Germany., Zeidan AM; Hematology Section, Department of Internal Medicine Yale School of Medicine New Haven USA., Komrokji RS; Department of Malignant Hematology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA., Della Porta MG; IRCCS Humanitas Research Hospital Rozzano Milan Italy.; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy.
Corporate Authors: An international study on behalf of GenoMed4all, Synthema, and icMDS consortia
Source: HemaSphere [Hemasphere] 2026 Jun 22; Vol. 10 (6), pp. e70406. Date of Electronic Publication: 2026 Jun 22 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101740619 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-9241 (Electronic) Linking ISSN: 25729241 NLM ISO Abbreviation: Hemasphere Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42339339
AccessLevel: 2
PubType: Academic Journal
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: Real-world, multi-omics validation of the clinical relevance of molecular taxonomy for myelodysplastic syndromes (MDS).
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Maggioni+G%22">Maggioni G</searchLink>; IRCCS Humanitas Research Hospital Rozzano Milan Italy.<br /><searchLink fieldCode="AU" term="%22Todisco+G%22">Todisco G</searchLink>; IRCCS Humanitas Research Hospital Rozzano Milan Italy.; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy.<br /><searchLink fieldCode="AU" term="%22Sauta+E%22">Sauta E</searchLink>; IRCCS Humanitas Research Hospital Rozzano Milan Italy.<br /><searchLink fieldCode="AU" term="%22Lanino+L%22">Lanino L</searchLink>; Hematology Section, Department of Internal Medicine Yale School of Medicine New Haven USA.<br /><searchLink fieldCode="AU" term="%22Ball+S%22">Ball S</searchLink>; Vanderbilt Ingram Cancer Center and Vanderbilt University School of Medicine Nashville Tennessee USA.<br /><searchLink fieldCode="AU" term="%22Bewersdorf+JP%22">Bewersdorf JP</searchLink>; Hematology Section, Department of Internal Medicine Yale School of Medicine New Haven USA.<br /><searchLink fieldCode="AU" term="%22Kewan+T%22">Kewan T</searchLink>; Hematology Section, Department of Internal Medicine Yale School of Medicine New Haven USA.<br /><searchLink fieldCode="AU" term="%22Al+Ali+NH%22">Al Ali NH</searchLink>; Department of Malignant Hematology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA.<br /><searchLink fieldCode="AU" term="%22Fenaux+P%22">Fenaux P</searchLink>; Hôpital Saint-Louis Université Paris Cité Paris France.<br /><searchLink fieldCode="AU" term="%22Platzbecker+U%22">Platzbecker U</searchLink>; Universitätsklinikum Carl Gustav Carus Dresden Germany.<br /><searchLink fieldCode="AU" term="%22Santini+V%22">Santini V</searchLink>; University of Florence Florence Italy.<br /><searchLink fieldCode="AU" term="%22Xie+Z%22">Xie Z</searchLink>; Department of Malignant Hematology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA.<br /><searchLink fieldCode="AU" term="%22Brunner+AM%22">Brunner AM</searchLink>; Leukemia Program, Massachusetts General Hospital Cancer Center Harvard Medical School Boston Massachusetts USA.<br /><searchLink fieldCode="AU" term="%22Kuykendall+AT%22">Kuykendall AT</searchLink>; Department of Malignant Hematology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA.<br /><searchLink fieldCode="AU" term="%22Bennett+JM%22">Bennett JM</searchLink>; University of Rochester Medical Center Rochester New York USA.<br /><searchLink fieldCode="AU" term="%22Buckstein+R%22">Buckstein R</searchLink>; Odette Cancer Centre Sunnybrook Health Sciences Centre Toronto Ontario Canada.<br /><searchLink fieldCode="AU" term="%22Bejar+R%22">Bejar R</searchLink>; University of California San Diego La Jolla California USA.<br /><searchLink fieldCode="AU" term="%22Carraway+HE%22">Carraway HE</searchLink>; Leukemia Program, Taussig Cancer Institute Cleveland Clinic Cleveland Ohio USA.<br /><searchLink fieldCode="AU" term="%22DeZern+AE%22">DeZern AE</searchLink>; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University Baltimore Maryland USA.<br /><searchLink fieldCode="AU" term="%22Griffiths+EA%22">Griffiths EA</searchLink>; Roswell Park Comprehensive Cancer Center Buffalo New York USA.<br /><searchLink fieldCode="AU" term="%22Halene+S%22">Halene S</searchLink>; Hematology Section, Department of Internal Medicine Yale School of Medicine New Haven USA.<br /><searchLink fieldCode="AU" term="%22Hasserjian+RP%22">Hasserjian RP</searchLink>; Massachusetts General Hospital Boston Massachusetts USA.<br /><searchLink fieldCode="AU" term="%22List+AF%22">List AF</searchLink>; Precision BioSciences Durham North Carolina USA.<br /><searchLink fieldCode="AU" term="%22Loghavi+S%22">Loghavi S</searchLink>; Department of Hematopathology The University of Texas MD Anderson Cancer Center Houston Texas USA.<br /><searchLink fieldCode="AU" term="%22Odenike+O%22">Odenike O</searchLink>; University of Chicago Medicine and University of Chicago Comprehensive Cancer Center Chicago Illinois USA.<br /><searchLink fieldCode="AU" term="%22Padron+E%22">Padron E</searchLink>; Department of Malignant Hematology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA.<br /><searchLink fieldCode="AU" term="%22Patnaik+MM%22">Patnaik MM</searchLink>; Department of Internal Medicine, Division of Hematology Mayo Clinic Rochester Minnesota USA.<br /><searchLink fieldCode="AU" term="%22Roboz+GJ%22">Roboz GJ</searchLink>; New York-Presbyterian/Weill Cornell Medicine New York New York USA.<br /><searchLink fieldCode="AU" term="%22Stahl+M%22">Stahl M</searchLink>; Hematology Section, Department of Internal Medicine Yale School of Medicine New Haven USA.<br /><searchLink fieldCode="AU" term="%22Sekeres+MA%22">Sekeres MA</searchLink>; Sylvester Comprehensive Cancer Center University of Miami Miami Florida USA.<br /><searchLink fieldCode="AU" term="%22Steensma+DP%22">Steensma DP</searchLink>; Ajax Therapeutics Cambridge Massachusetts USA.<br /><searchLink fieldCode="AU" term="%22Savona+MR%22">Savona MR</searchLink>; Vanderbilt Ingram Cancer Center and Vanderbilt University School of Medicine Nashville Tennessee USA.<br /><searchLink fieldCode="AU" term="%22Taylor+J%22">Taylor J</searchLink>; Sylvester Comprehensive Cancer Center University of Miami Miami Florida USA.<br /><searchLink fieldCode="AU" term="%22Xu+ML%22">Xu ML</searchLink>; Department of Pathology & Laboratory Medicine Yale School of Medicine New Haven Connecticut USA.<br /><searchLink fieldCode="AU" term="%22Sallman+DA%22">Sallman DA</searchLink>; Department of Malignant Hematology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA.<br /><searchLink fieldCode="AU" term="%22Nimer+SD%22">Nimer SD</searchLink>; Sylvester Comprehensive Cancer Center University of Miami Miami Florida USA.<br /><searchLink fieldCode="AU" term="%22Hourigan+CS%22">Hourigan CS</searchLink>; Virginia Tech FBRI Cancer Research Center Washington District of Columbia USA.<br /><searchLink fieldCode="AU" term="%22Wei+AH%22">Wei AH</searchLink>; Department of Haematology Peter MacCallum Cancer Centre, Melbourne Victoria Australia.<br /><searchLink fieldCode="AU" term="%22Campagna+A%22">Campagna A</searchLink>; IRCCS Humanitas Research Hospital Rozzano Milan Italy.<br /><searchLink fieldCode="AU" term="%22Ubezio+M%22">Ubezio M</searchLink>; IRCCS Humanitas Research Hospital Rozzano Milan Italy.<br /><searchLink fieldCode="AU" term="%22Riva+E%22">Riva E</searchLink>; IRCCS Humanitas Research Hospital Rozzano Milan Italy.<br /><searchLink fieldCode="AU" term="%22Ventura+D%22">Ventura D</searchLink>; IRCCS Humanitas Research Hospital Rozzano Milan Italy.<br /><searchLink fieldCode="AU" term="%22Pinocchio+N%22">Pinocchio N</searchLink>; IRCCS Humanitas Research Hospital Rozzano Milan Italy.<br /><searchLink fieldCode="AU" term="%22Zampini+M%22">Zampini M</searchLink>; IRCCS Humanitas Research Hospital Rozzano Milan Italy.<br /><searchLink fieldCode="AU" term="%22Buizza+A%22">Buizza A</searchLink>; IRCCS Humanitas Research Hospital Rozzano Milan Italy.; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy.<br /><searchLink fieldCode="AU" term="%22Russo+A%22">Russo A</searchLink>; IRCCS Humanitas Research Hospital Rozzano Milan Italy.<br /><searchLink fieldCode="AU" term="%22Pesce+F%22">Pesce F</searchLink>; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy.<br /><searchLink fieldCode="AU" term="%22D'Amico+S%22">D'Amico S</searchLink>; IRCCS Humanitas Research Hospital Rozzano Milan Italy.<br /><searchLink fieldCode="AU" term="%22Asti+G%22">Asti G</searchLink>; 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Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy.<br /><searchLink fieldCode="AU" term="%22Di+Matteo+M%22">Di Matteo M</searchLink>; IRCCS Humanitas Research Hospital Rozzano Milan Italy.; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy.<br /><searchLink fieldCode="AU" term="%22Brindisi+M%22">Brindisi M</searchLink>; IRCCS Humanitas Research Hospital Rozzano Milan Italy.<br /><searchLink fieldCode="AU" term="%22Manes+N%22">Manes N</searchLink>; IRCCS Humanitas Research Hospital Rozzano Milan Italy.<br /><searchLink fieldCode="AU" term="%22Milanesi+C%22">Milanesi C</searchLink>; IRCCS Humanitas Research Hospital Rozzano Milan Italy.<br /><searchLink fieldCode="AU" term="%22Crisafulli+L%22">Crisafulli L</searchLink>; IRCCS Humanitas Research Hospital Rozzano Milan Italy.<br /><searchLink fieldCode="AU" term="%22Ficara+F%22">Ficara F</searchLink>; IRCCS Humanitas Research Hospital Rozzano Milan Italy.<br /><searchLink fieldCode="AU" term="%22Castellani+G%22">Castellani G</searchLink>; 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Department of Hematology VU University Medical Center-Cancer Center Amsterdam Netherlands.<br /><searchLink fieldCode="AU" term="%22Daver+N%22">Daver N</searchLink>; Department of Leukemia The University of Texas MD Anderson Cancer Center Houston Texas USA.<br /><searchLink fieldCode="AU" term="%22Rozman+M%22">Rozman M</searchLink>; Hospital Clínic Barcelona Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Orfao+A%22">Orfao A</searchLink>; Department of Hematology Hospital Universitario de Salamanca Salamanca Spain.<br /><searchLink fieldCode="AU" term="%22Wang+SA%22">Wang SA</searchLink>; Department of Hematopathology The University of Texas MD Anderson Cancer Center Houston Texas USA.<br /><searchLink fieldCode="AU" term="%22Foucar+K%22">Foucar K</searchLink>; University of New Mexico Albuquerque New Mexico USA.<br /><searchLink fieldCode="AU" term="%22Iastrebner+M%22">Iastrebner M</searchLink>; Sanatorio Sagrado Corazón Buenos Aires Argentina.<br /><searchLink fieldCode="AU" term="%22Scheinberg+P%22">Scheinberg P</searchLink>; 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Department of Hematology, Oncology, and Clinical Immunology Heinrich-Heine-University Düsseldorf Germany.<br /><searchLink fieldCode="AU" term="%22Garcia-Manero+G%22">Garcia-Manero G</searchLink>; Department of Leukemia The University of Texas MD Anderson Cancer Center Houston Texas USA.<br /><searchLink fieldCode="AU" term="%22Kordasti+S%22">Kordasti S</searchLink>; Department of Haematology Guy's Hospital & Comprehensive Cancer Centre, King's College London UK.<br /><searchLink fieldCode="AU" term="%22Haferlach+T%22">Haferlach T</searchLink>; MLL Munich Leukemia Laboratory Munich Germany.<br /><searchLink fieldCode="AU" term="%22Zeidan+AM%22">Zeidan AM</searchLink>; Hematology Section, Department of Internal Medicine Yale School of Medicine New Haven USA.<br /><searchLink fieldCode="AU" term="%22Komrokji+RS%22">Komrokji RS</searchLink>; Department of Malignant Hematology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA.<br /><searchLink fieldCode="AU" term="%22Della+Porta+MG%22">Della Porta MG</searchLink>; IRCCS Humanitas Research Hospital Rozzano Milan Italy.; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy.
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  Data: <searchLink fieldCode="JN" term="%22101740619%22">HemaSphere</searchLink> [Hemasphere] 2026 Jun 22; Vol. 10 (6), pp. e70406. <i>Date of Electronic Publication: </i>2026 Jun 22 (<i>Print Publication: </i>2026).
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        Value: 10.1002/hem3.70406
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        Text: English
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      – TitleFull: Real-world, multi-omics validation of the clinical relevance of molecular taxonomy for myelodysplastic syndromes (MDS).
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      – PersonEntity:
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      – PersonEntity:
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      – PersonEntity:
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      – PersonEntity:
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            NameFull: Germing U
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    IsPartOfRelationships:
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          Dates:
            – D: 22
              M: 06
              Text: 2026 Jun 22
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 2572-9241
          Numbering:
            – Type: volume
              Value: 10
            – Type: issue
              Value: 6
          Titles:
            – TitleFull: HemaSphere
              Type: main
ResultId 1