Loss of essential outer membrane functions causes drug hypersensitization in Acinetobacter baumannii overexpressing multidrug efflux pumps.

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Title: Loss of essential outer membrane functions causes drug hypersensitization in Acinetobacter baumannii overexpressing multidrug efflux pumps.
Authors: Hamami E; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA., Huo W; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA., Neal K; Department of Biochemistry, Curry College, Milton, Massachusetts, USA., Neisewander I; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA., Shivangi; Department of Pharmacology, Physiology, and Neuroscience, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA., Freundlich JS; Department of Pharmacology, Physiology, and Neuroscience, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA.; Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenco Center for the Study of Emerging and Re-Emerging Pathogens, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA., Geisinger E; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.; Department of Biology, Northeastern University, Boston, Massachusetts, USA., Isberg RR; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.
Source: MBio [mBio] 2026 Jun 24, pp. e0090226. Date of Electronic Publication: 2026 Jun 24.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Loss of essential outer membrane functions causes drug hypersensitization in Acinetobacter baumannii overexpressing multidrug efflux pumps.
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  Data: <searchLink fieldCode="AU" term="%22Hamami+E%22">Hamami E</searchLink>; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Huo+W%22">Huo W</searchLink>; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Neal+K%22">Neal K</searchLink>; Department of Biochemistry, Curry College, Milton, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Neisewander+I%22">Neisewander I</searchLink>; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Shivangi%22">Shivangi</searchLink>; Department of Pharmacology, Physiology, and Neuroscience, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Freundlich+JS%22">Freundlich JS</searchLink>; Department of Pharmacology, Physiology, and Neuroscience, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA.; Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenco Center for the Study of Emerging and Re-Emerging Pathogens, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Geisinger+E%22">Geisinger E</searchLink>; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.; Department of Biology, Northeastern University, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Isberg+RR%22">Isberg RR</searchLink>; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.
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        Value: 10.1128/mbio.00902-26
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              Text: 2026 Jun 24
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