Trimerization of CD40L-specific affibody molecules using collagen domains enhances target binding and CD40 blockade.
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| Title: | Trimerization of CD40L-specific affibody molecules using collagen domains enhances target binding and CD40 blockade. |
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| Authors: | Westerberg C; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, 106 91, Sweden., Sorini C; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, 171 76, Sweden., Al-Haddad M; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, 106 91, Sweden., Mehari H; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, 106 91, Sweden., Ståhl S; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, 106 91, Sweden., Jagodic M; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, 171 76, Sweden., Löfblom J; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, 106 91, Sweden. lofblom@kth.se. |
| Source: | Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2026 Jun 24; Vol. 83 (1). Date of Electronic Publication: 2026 Jun 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1420-9071 |
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| DOI: | 10.1007/s00018-026-06301-2 |
