Trimerization of CD40L-specific affibody molecules using collagen domains enhances target binding and CD40 blockade.

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Title: Trimerization of CD40L-specific affibody molecules using collagen domains enhances target binding and CD40 blockade.
Authors: Westerberg C; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, 106 91, Sweden., Sorini C; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, 171 76, Sweden., Al-Haddad M; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, 106 91, Sweden., Mehari H; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, 106 91, Sweden., Ståhl S; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, 106 91, Sweden., Jagodic M; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, 171 76, Sweden., Löfblom J; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, 106 91, Sweden. lofblom@kth.se.
Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2026 Jun 24; Vol. 83 (1). Date of Electronic Publication: 2026 Jun 24.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Trimerization of CD40L-specific affibody molecules using collagen domains enhances target binding and CD40 blockade.
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  Data: <searchLink fieldCode="AU" term="%22Westerberg+C%22">Westerberg C</searchLink>; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, 106 91, Sweden.<br /><searchLink fieldCode="AU" term="%22Sorini+C%22">Sorini C</searchLink>; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, 171 76, Sweden.<br /><searchLink fieldCode="AU" term="%22Al-Haddad+M%22">Al-Haddad M</searchLink>; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, 106 91, Sweden.<br /><searchLink fieldCode="AU" term="%22Mehari+H%22">Mehari H</searchLink>; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, 106 91, Sweden.<br /><searchLink fieldCode="AU" term="%22Ståhl+S%22">Ståhl S</searchLink>; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, 106 91, Sweden.<br /><searchLink fieldCode="AU" term="%22Jagodic+M%22">Jagodic M</searchLink>; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, 171 76, Sweden.<br /><searchLink fieldCode="AU" term="%22Löfblom+J%22">Löfblom J</searchLink>; Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, 106 91, Sweden. lofblom@kth.se.
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  Data: <searchLink fieldCode="JN" term="%229705402%22">Cellular and molecular life sciences : CMLS</searchLink> [Cell Mol Life Sci] 2026 Jun 24; Vol. 83 (1). <i>Date of Electronic Publication: </i>2026 Jun 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>9705402 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1420-9071 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221420682X%22">1420682X </searchLink><i>NLM ISO Abbreviation: </i>Cell Mol Life Sci <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00018-026-06301-2
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              Text: 2026 Jun 24
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