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Severe asthma and remission prospects in Europe (SHARP): insights from a multicentre observational study based on the European Severe Asthma Registry.

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Title: Severe asthma and remission prospects in Europe (SHARP): insights from a multicentre observational study based on the European Severe Asthma Registry.
Authors: Fouka E; Division for Lung and Airway Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Lung Laboratory, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; 2nd Department of Respiratory Medicine, University General Hospital Attikon, National and Kapodistrian University of Athens, Athens, Greece., Bansal AT; Acclarogen, St John's Innovation Centre, Cambridge, UK., Håkansson KEJ; Department of Respiratory Medicine and Infectious Diseases - Bispebjerg, Copenhagen University Hospital, Copenhagen, Denmark., Jaun F; University Institute of Internal Medicine, Cantonal Hospital Baselland, Liestal, Switzerland; Faculty of Medicine, University of Basel, Basel, Switzerland., Louis R; Department of Pneumology-Allergology, CHU of Liège, GIGAI(3) Pneumology Research Group, Liège University, Liège, Belgium., Hanon S; UZ Brussel/Vrije Universiteit Brussel Lung Research Unit, Vitality Research Group, Vrije Universiteit Brussel, Brussels, Belgium; Respiratory Division, Universitair Ziekenhuis Brussel, Brussels, Belgium., Brusselle G; Department of Respiratory Medicine, Ghent University Hospital, Gent, Belgium., Ziant S; Department of Pneumology-Allergology, CHU of Liège, GIGAI(3) Pneumology Research Group, Liège University, Liège, Belgium., Paulus V; Department of Pneumology-Allergology, CHU of Liège, GIGAI(3) Pneumology Research Group, Liège University, Liège, Belgium., Popović-Grle S; Clinic for pulmonary diseases Jordanovac, University Hospital Centre Zagreb, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia., Pavlisa G; Clinic for pulmonary diseases Jordanovac, University Hospital Centre Zagreb, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia., Lampalo M; Clinic for pulmonary diseases Jordanovac, University Hospital Centre Zagreb, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia., Vergles M; Department of Pulmonology, University Hospital Dubrava, Zagreb, Croatia., Kasap EB; Department of Pulmonology, General Hospital Zadar, Zadar, Croatia., Sedlak V; Department of Pneumonology, University Hospital Hradec Králové, Hradec Králové, Czech Republic., Søndergaard M; Department of Respiratory Medicine and Infectious Diseases - Bispebjerg, Copenhagen University Hospital, Copenhagen, Denmark., Hansen S; Department of Respiratory Medicine and Infectious Diseases - Bispebjerg, Copenhagen University Hospital, Copenhagen, Denmark., Sergejeva S; The North Estonia Medical Centre, Tallinn, Estonia., Perotin JM; Université de Reims Champagne-Ardenne, INSERM, CHU de Reims, P3Cell UMR-S1250, Reims, France., Taillé C; Service de Pneumologie, Allergologie et Transplantation, Hôpital Bichat, AP-HP, Paris, France; INSERM UMR 1149, Université Paris Cité, CRISALIS Network, Paris, France., Devouassoux G; Service de Pneumologie, Hôpital de la Croix Rousse, HCL, CRISALIS F-CRIN network, VIRPATH INSERM 1111, Université Claude Bernard, Lyon, France., Giboin C; AP-HP, Hôpital Pitié Salpêtrière, INSERM, Centre de Pharmacoépidémiologie (Cephepi), Paris, France., Klising E; AP-HP, Hôpital Pitié Salpêtrière, INSERM, Centre de Pharmacoépidémiologie (Cephepi), Paris, France., Estellat C; Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, équipe PEPITES, AP-HP, Hôpital Pitié Salpêtrière, Centre de Pharmacoépidémiologie (Cephépi), Paris, France., Metdaoui D; AP-HP, Hôpital Pitié Salpêtrière, INSERM, Centre de Pharmacoépidémiologie (Cephepi), Paris, France., Hamelmann E; Department of Paediatrics, Children's Center Bethel, University Hospital OWL, University Bielefeld, Bielefeld, Germany., Samitas K; 7th Respiratory Dept and Asthma Center, Athens Chest Hospital Sotiria, Athens, Greece., Porpodis K; Pulmonary Department, G Papanikolaou General Hospital, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece., Zervas E; 7th Respiratory Dept and Asthma Center, Athens Chest Hospital Sotiria, Athens, Greece., Gaga M; 1st Respiratory Medicine Department, Hygeia Hospital, Athens, Greece., Csoma Z; National Koranyi Institute of Pulmonology, Budapest, Hungary., Horvath I; National Koranyi Institute of Pulmonology, Budapest, Hungary; Department of Pulmonology, University of Debrecen, Debrecen, Hungary., Lúdvíksdóttir D; Department of Respiratory Medicine, Landspítali University Hospital, University of Iceland, Reykjavík, Iceland., Sigurdardóttir KD; Department of Respiratory Medicine, Landspítali University Hospital, University of Iceland, Reykjavík, Iceland., Canonica GW; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy; Personalized Medicine, Asthma and Allergy-IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Heffler E; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy; Personalized Medicine, Asthma and Allergy-IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Cardini C; Fondazione per la Salute Respiratoria della Società Italiana di Pneumologia SIP-IRS, Milan, Italy., Alloni A; Biomeris SRL, Pavia, Italy., Kroiča I; Riga East Clinical University Hospital, Riga, Latvia., Matisa D; Pauls Stradiņš Clinical University Hospital, Riga, Latvia., Bieksiene K; Department of Pulmonology, Lithuanian University of Health Sciences, Kaunas, Lithuania., Palacionyte J; Department of Pulmonology, Lithuanian University of Health Sciences, Kaunas, Lithuania., Christian N; Information Technology for Translational Medicine SA, Esch sur Alzette, Luxembourg., Tching R; Information Technology for Translational Medicine SA, Esch sur Alzette, Luxembourg., Boudewijn I; Department of Pulmonology, Frisius Medical Center, Leeuwarden, Netherlands., Sont JK; Department of Biomedical Data Sciences, Caecilia Institute for Population Health and Data Sciences, Leiden University Medical Centre, Leiden, Netherlands., Hashimoto S; Department of Respiratory Medicine, Amsterdam University Medical Center,Amsterdam, Netherlands., Kuna P; Department of Internal Medicine, Asthma andAllergy, Medical Universityof Lodz, Lodz, Poland., Morawska M; Department of Internal Medicine, Asthma andAllergy, Medical Universityof Lodz, Lodz, Poland., Loureiro CC; Pulmonology Unit, Unidade Localde Saúde de Coimbra, EPE, Coimbra, Portugal; Faculdade de Medicina, Universidade de Coimbra, Coimbra, Portugal., Fonseca JA; RISE- Health Research Network, Department of Community Medicine, Information and Health Decisions, Faculty of Medicine of the University of Porto, Porto, Portugal., Canhoto D; Pulmonology Unit, Unidade Localde Saúde de Coimbra, EPE, Coimbra, Portugal; Faculdade de Medicina, Universidade de Coimbra, Coimbra, Portugal., Santos H; Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal., Mendes A; Serviço de Imunoalergologia, Departamento Torax, Unidade Multidisciplinar de Asma Grave, Unidade Local de Saúde Santa Maria, Lisbon, Portugal., Belchior I; Serviço de Pneumologia-ULS Algarve, Portimão, Portugal., Lopes C; Instituto de Saúde Ambiental, Faculdade de Medicina de Lisboa, Lisbon, Portugal; Unidade Multidisciplinar de Asma Grave, Unidade Local de Saúde Santa Maria, Lisbon, Portugal., Mihaltan F; National Institute of Pneumology, Bucharest, Romania., Hromis S; Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia; Institute for Pulmonary Diseases of Vojvodina, Sremska Kamenica, Serbia., Stjepanovic M; Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Clinic of Pulmonology, University Clinical Center of Serbia, Belgrade, Serbia., Cupurdija V; Department of Internal medicine, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia; Clinic for Pulmonology, University Clinical Center Kragujevac, Kragujevac, Serbia., Tomic-Spiric V; Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Clinic of Allergology and Immunology, University Clinical Center of Serbia, Belgrade, Serbia., Skrgat S; Department of Pulmonary Diseases and Allergy, University Medical Centre Ljubljana, Ljubljana, Slovenia; Medical Faculty, University of Ljubljana, Ljubljana, Slovenia., Kopac P; Medical Faculty, University of Ljubljana, Ljubljana, Slovenia; University Clinic of Respiratory and Allergic Diseases Golnik, Golnik, Slovenia., Ramos-Barbon D; Hospital de la Santa Creu i Sant Pau and Biomedical Research Institute Sant Pau, Barcelona, Spain., Pérez de Llano L; Servicio de Neumología, University Hospital Lucus Augusti, EOXI Lugo, Monteforte, Cervo, Spain., Garcia VL; Evidenze Clinical Research, Madrid, Spain., Morenos Martos D; Evidenze Clinical Research, Madrid, Spain., Dahlén B; Clinical Lung- and Allergy Research Unit, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden; Department of Respiratory Medicine and Allergy, Severe Asthma Center, Karolinska University Hospital Huddinge, Stockholm, Sweden., Yasinska V; Clinical Lung- and Allergy Research Unit, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden; Karolinska Severe Asthma Center, Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden., Tenselius O; Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden., Janson C; Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Sweden., Egesten A; Department of Clinical Sciences Lund, Respiratory Medicine, Allergology and Palliative Medicine, Lund University and Skåne University Hospital, Lund, Sweden., Richter J; Department of Clinical Sciences Lund, Respiratory Medicine, Allergology and Palliative Medicine, Lund University and Skåne University Hospital, Lund, Sweden., Emilsson ÖI; Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Sweden; Faculty of Medicine, University of Iceland, Reykjavík, Iceland., Leuppi J; University Institute of Internal Medicine, Cantonal Hospital Baselland, Liestal, Switzerland; Faculty of Medicine, University of Basel, Basel, Switzerland., Gemicioglu B; Department of Pulmonary Diseases, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Türkiye., Celik G; Division of Immunology and Allergy, Ankara University School of Medicine, Ankara, Türkiye., Damadoglu E; Department of Pulmonary Diseases, Division of Allergy and Clinical Immunology, Hacettepe University, Faculty of Medicine, Ankara, Türkiye., Goksel O; Department of Pulmonary Medicine, Head Division of Immunology and Allergy, Laboratory of Occupational and Environmental Respiratory Diseases and Asthma, Ege University, Faculty of Medicine, Izmir, Türkiye; EgeSAM-Ege University Translational Pulmonary Research Center, Izmir, Türkiye., Heaney L; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University, Belfast, UK., Busby J; Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University, Belfast, UK., Redmond C; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University, Belfast, UK., Masoli M; Respiratory Medicine, Royal Devon University Healthcare NHS Foundation, Exeter, UK., Chaudhuri R; Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK; School of Infection and Immunity, University of Glasgow, Glasgow, UK., Dennison P; Respiratory Medicine, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Doe S; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK., Kurukulaaratchy R; Respiratory Medicine, University Hospital Southampton NHS Foundation Trust, Southampton, UK; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre at University Hospital Southampton NHS Foundation Trust, Southampton, UK; The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, UK., Bel E; Department of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., Djukanovic R; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre at University Hospital Southampton NHS Foundation Trust, Southampton, UK., Bourdin A; PhyMedExp, (INSERM U 1046, CNRS UMR9214), Montpellier University, Montpellier, France; Department of Respiratory Diseases, Montpellier University Hospital, Arnaud de Villeneuve Hospital, Montpellier, France., Ten Brinke A; Department of Pulmonology, Frisius Medical Center, Leeuwarden, Netherlands., Schleich F; Department of Pneumology-Allergology, CHU of Liège, Liége, Belgium; GIGAI(3), Pneumology Research Group, Liège University, Liège, Belgium; Exercise Physiology Lab, Department of Physical Activity and Rehabilitation Sciences, University of Liège, Liège, Belgium., Porsbjerg C; Department of Respiratory Medicine and Infectious Diseases - Bispebjerg, Copenhagen University Hospital, Copenhagen, Denmark., Bossios A; Division for Lung and Airway Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Lung Laboratory, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; Karolinska Severe Asthma Center, Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden. Electronic address: apostolos.bossios@ki.se.
Source: The Lancet. Respiratory medicine [Lancet Respir Med] 2026 Jun 24. Date of Electronic Publication: 2026 Jun 24.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101605555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2619 (Electronic) Linking ISSN: 22132600 NLM ISO Abbreviation: Lancet Respir Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Severe asthma and remission prospects in Europe (SHARP): insights from a multicentre observational study based on the European Severe Asthma Registry.
– Name: Author
  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Fouka+E%22">Fouka E</searchLink>; Division for Lung and Airway Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Lung Laboratory, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; 2nd Department of Respiratory Medicine, University General Hospital Attikon, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Bansal+AT%22">Bansal AT</searchLink>; Acclarogen, St John's Innovation Centre, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Håkansson+KEJ%22">Håkansson KEJ</searchLink>; Department of Respiratory Medicine and Infectious Diseases - Bispebjerg, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Jaun+F%22">Jaun F</searchLink>; University Institute of Internal Medicine, Cantonal Hospital Baselland, Liestal, Switzerland; Faculty of Medicine, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Louis+R%22">Louis R</searchLink>; Department of Pneumology-Allergology, CHU of Liège, GIGAI(3) Pneumology Research Group, Liège University, Liège, Belgium.<br /><searchLink fieldCode="AU" term="%22Hanon+S%22">Hanon S</searchLink>; UZ Brussel/Vrije Universiteit Brussel Lung Research Unit, Vitality Research Group, Vrije Universiteit Brussel, Brussels, Belgium; Respiratory Division, Universitair Ziekenhuis Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Brusselle+G%22">Brusselle G</searchLink>; Department of Respiratory Medicine, Ghent University Hospital, Gent, Belgium.<br /><searchLink fieldCode="AU" term="%22Ziant+S%22">Ziant S</searchLink>; Department of Pneumology-Allergology, CHU of Liège, GIGAI(3) Pneumology Research Group, Liège University, Liège, Belgium.<br /><searchLink fieldCode="AU" term="%22Paulus+V%22">Paulus V</searchLink>; Department of Pneumology-Allergology, CHU of Liège, GIGAI(3) Pneumology Research Group, Liège University, Liège, Belgium.<br /><searchLink fieldCode="AU" term="%22Popović-Grle+S%22">Popović-Grle S</searchLink>; Clinic for pulmonary diseases Jordanovac, University Hospital Centre Zagreb, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Pavlisa+G%22">Pavlisa G</searchLink>; Clinic for pulmonary diseases Jordanovac, University Hospital Centre Zagreb, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Lampalo+M%22">Lampalo M</searchLink>; Clinic for pulmonary diseases Jordanovac, University Hospital Centre Zagreb, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Vergles+M%22">Vergles M</searchLink>; Department of Pulmonology, University Hospital Dubrava, Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Kasap+EB%22">Kasap EB</searchLink>; Department of Pulmonology, General Hospital Zadar, Zadar, Croatia.<br /><searchLink fieldCode="AU" term="%22Sedlak+V%22">Sedlak V</searchLink>; Department of Pneumonology, University Hospital Hradec Králové, Hradec Králové, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Søndergaard+M%22">Søndergaard M</searchLink>; Department of Respiratory Medicine and Infectious Diseases - Bispebjerg, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Hansen+S%22">Hansen S</searchLink>; Department of Respiratory Medicine and Infectious Diseases - Bispebjerg, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Sergejeva+S%22">Sergejeva S</searchLink>; The North Estonia Medical Centre, Tallinn, Estonia.<br /><searchLink fieldCode="AU" term="%22Perotin+JM%22">Perotin JM</searchLink>; Université de Reims Champagne-Ardenne, INSERM, CHU de Reims, P3Cell UMR-S1250, Reims, France.<br /><searchLink fieldCode="AU" term="%22Taillé+C%22">Taillé C</searchLink>; Service de Pneumologie, Allergologie et Transplantation, Hôpital Bichat, AP-HP, Paris, France; INSERM UMR 1149, Université Paris Cité, CRISALIS Network, Paris, France.<br /><searchLink fieldCode="AU" term="%22Devouassoux+G%22">Devouassoux G</searchLink>; Service de Pneumologie, Hôpital de la Croix Rousse, HCL, CRISALIS F-CRIN network, VIRPATH INSERM 1111, Université Claude Bernard, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Giboin+C%22">Giboin C</searchLink>; AP-HP, Hôpital Pitié Salpêtrière, INSERM, Centre de Pharmacoépidémiologie (Cephepi), Paris, France.<br /><searchLink fieldCode="AU" term="%22Klising+E%22">Klising E</searchLink>; AP-HP, Hôpital Pitié Salpêtrière, INSERM, Centre de Pharmacoépidémiologie (Cephepi), Paris, France.<br /><searchLink fieldCode="AU" term="%22Estellat+C%22">Estellat C</searchLink>; Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, équipe PEPITES, AP-HP, Hôpital Pitié Salpêtrière, Centre de Pharmacoépidémiologie (Cephépi), Paris, France.<br /><searchLink fieldCode="AU" term="%22Metdaoui+D%22">Metdaoui D</searchLink>; AP-HP, Hôpital Pitié Salpêtrière, INSERM, Centre de Pharmacoépidémiologie (Cephepi), Paris, France.<br /><searchLink fieldCode="AU" term="%22Hamelmann+E%22">Hamelmann E</searchLink>; Department of Paediatrics, Children's Center Bethel, University Hospital OWL, University Bielefeld, Bielefeld, Germany.<br /><searchLink fieldCode="AU" term="%22Samitas+K%22">Samitas K</searchLink>; 7th Respiratory Dept and Asthma Center, Athens Chest Hospital Sotiria, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Porpodis+K%22">Porpodis K</searchLink>; Pulmonary Department, G Papanikolaou General Hospital, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Zervas+E%22">Zervas E</searchLink>; 7th Respiratory Dept and Asthma Center, Athens Chest Hospital Sotiria, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Gaga+M%22">Gaga M</searchLink>; 1st Respiratory Medicine Department, Hygeia Hospital, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Csoma+Z%22">Csoma Z</searchLink>; National Koranyi Institute of Pulmonology, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Horvath+I%22">Horvath I</searchLink>; National Koranyi Institute of Pulmonology, Budapest, Hungary; Department of Pulmonology, University of Debrecen, Debrecen, Hungary.<br /><searchLink fieldCode="AU" term="%22Lúdvíksdóttir+D%22">Lúdvíksdóttir D</searchLink>; Department of Respiratory Medicine, Landspítali University Hospital, University of Iceland, Reykjavík, Iceland.<br /><searchLink fieldCode="AU" term="%22Sigurdardóttir+KD%22">Sigurdardóttir KD</searchLink>; Department of Respiratory Medicine, Landspítali University Hospital, University of Iceland, Reykjavík, Iceland.<br /><searchLink fieldCode="AU" term="%22Canonica+GW%22">Canonica GW</searchLink>; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy; Personalized Medicine, Asthma and Allergy-IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Heffler+E%22">Heffler E</searchLink>; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy; Personalized Medicine, Asthma and Allergy-IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cardini+C%22">Cardini C</searchLink>; Fondazione per la Salute Respiratoria della Società Italiana di Pneumologia SIP-IRS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Alloni+A%22">Alloni A</searchLink>; Biomeris SRL, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Kroiča+I%22">Kroiča I</searchLink>; Riga East Clinical University Hospital, Riga, Latvia.<br /><searchLink fieldCode="AU" term="%22Matisa+D%22">Matisa D</searchLink>; Pauls Stradiņš Clinical University Hospital, Riga, Latvia.<br /><searchLink fieldCode="AU" term="%22Bieksiene+K%22">Bieksiene K</searchLink>; Department of Pulmonology, Lithuanian University of Health Sciences, Kaunas, Lithuania.<br /><searchLink fieldCode="AU" term="%22Palacionyte+J%22">Palacionyte J</searchLink>; Department of Pulmonology, Lithuanian University of Health Sciences, Kaunas, Lithuania.<br /><searchLink fieldCode="AU" term="%22Christian+N%22">Christian N</searchLink>; Information Technology for Translational Medicine SA, Esch sur Alzette, Luxembourg.<br /><searchLink fieldCode="AU" term="%22Tching+R%22">Tching R</searchLink>; Information Technology for Translational Medicine SA, Esch sur Alzette, Luxembourg.<br /><searchLink fieldCode="AU" term="%22Boudewijn+I%22">Boudewijn I</searchLink>; Department of Pulmonology, Frisius Medical Center, Leeuwarden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Sont+JK%22">Sont JK</searchLink>; Department of Biomedical Data Sciences, Caecilia Institute for Population Health and Data Sciences, Leiden University Medical Centre, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Hashimoto+S%22">Hashimoto S</searchLink>; Department of Respiratory Medicine, Amsterdam University Medical Center,Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Kuna+P%22">Kuna P</searchLink>; Department of Internal Medicine, Asthma andAllergy, Medical Universityof Lodz, Lodz, Poland.<br /><searchLink fieldCode="AU" term="%22Morawska+M%22">Morawska M</searchLink>; Department of Internal Medicine, Asthma andAllergy, Medical Universityof Lodz, Lodz, Poland.<br /><searchLink fieldCode="AU" term="%22Loureiro+CC%22">Loureiro CC</searchLink>; Pulmonology Unit, Unidade Localde Saúde de Coimbra, EPE, Coimbra, Portugal; Faculdade de Medicina, Universidade de Coimbra, Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Fonseca+JA%22">Fonseca JA</searchLink>; RISE- Health Research Network, Department of Community Medicine, Information and Health Decisions, Faculty of Medicine of the University of Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Canhoto+D%22">Canhoto D</searchLink>; Pulmonology Unit, Unidade Localde Saúde de Coimbra, EPE, Coimbra, Portugal; Faculdade de Medicina, Universidade de Coimbra, Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Santos+H%22">Santos H</searchLink>; Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Mendes+A%22">Mendes A</searchLink>; Serviço de Imunoalergologia, Departamento Torax, Unidade Multidisciplinar de Asma Grave, Unidade Local de Saúde Santa Maria, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Belchior+I%22">Belchior I</searchLink>; Serviço de Pneumologia-ULS Algarve, Portimão, Portugal.<br /><searchLink fieldCode="AU" term="%22Lopes+C%22">Lopes C</searchLink>; Instituto de Saúde Ambiental, Faculdade de Medicina de Lisboa, Lisbon, Portugal; Unidade Multidisciplinar de Asma Grave, Unidade Local de Saúde Santa Maria, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Mihaltan+F%22">Mihaltan F</searchLink>; National Institute of Pneumology, Bucharest, Romania.<br /><searchLink fieldCode="AU" term="%22Hromis+S%22">Hromis S</searchLink>; Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia; Institute for Pulmonary Diseases of Vojvodina, Sremska Kamenica, Serbia.<br /><searchLink fieldCode="AU" term="%22Stjepanovic+M%22">Stjepanovic M</searchLink>; Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Clinic of Pulmonology, University Clinical Center of Serbia, Belgrade, Serbia.<br /><searchLink fieldCode="AU" term="%22Cupurdija+V%22">Cupurdija V</searchLink>; Department of Internal medicine, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia; Clinic for Pulmonology, University Clinical Center Kragujevac, Kragujevac, Serbia.<br /><searchLink fieldCode="AU" term="%22Tomic-Spiric+V%22">Tomic-Spiric V</searchLink>; Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Clinic of Allergology and Immunology, University Clinical Center of Serbia, Belgrade, Serbia.<br /><searchLink fieldCode="AU" term="%22Skrgat+S%22">Skrgat S</searchLink>; Department of Pulmonary Diseases and Allergy, University Medical Centre Ljubljana, Ljubljana, Slovenia; Medical Faculty, University of Ljubljana, Ljubljana, Slovenia.<br /><searchLink fieldCode="AU" term="%22Kopac+P%22">Kopac P</searchLink>; Medical Faculty, University of Ljubljana, Ljubljana, Slovenia; University Clinic of Respiratory and Allergic Diseases Golnik, Golnik, Slovenia.<br /><searchLink fieldCode="AU" term="%22Ramos-Barbon+D%22">Ramos-Barbon D</searchLink>; Hospital de la Santa Creu i Sant Pau and Biomedical Research Institute Sant Pau, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Pérez+de+Llano+L%22">Pérez de Llano L</searchLink>; Servicio de Neumología, University Hospital Lucus Augusti, EOXI Lugo, Monteforte, Cervo, Spain.<br /><searchLink fieldCode="AU" term="%22Garcia+VL%22">Garcia VL</searchLink>; Evidenze Clinical Research, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Morenos+Martos+D%22">Morenos Martos D</searchLink>; Evidenze Clinical Research, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Dahlén+B%22">Dahlén B</searchLink>; Clinical Lung- and Allergy Research Unit, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden; Department of Respiratory Medicine and Allergy, Severe Asthma Center, Karolinska University Hospital Huddinge, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Yasinska+V%22">Yasinska V</searchLink>; Clinical Lung- and Allergy Research Unit, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden; Karolinska Severe Asthma Center, Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Tenselius+O%22">Tenselius O</searchLink>; Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Janson+C%22">Janson C</searchLink>; Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Sweden.<br /><searchLink fieldCode="AU" term="%22Egesten+A%22">Egesten A</searchLink>; Department of Clinical Sciences Lund, Respiratory Medicine, Allergology and Palliative Medicine, Lund University and Skåne University Hospital, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Richter+J%22">Richter J</searchLink>; Department of Clinical Sciences Lund, Respiratory Medicine, Allergology and Palliative Medicine, Lund University and Skåne University Hospital, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Emilsson+ÖI%22">Emilsson ÖI</searchLink>; Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Sweden; Faculty of Medicine, University of Iceland, Reykjavík, Iceland.<br /><searchLink fieldCode="AU" term="%22Leuppi+J%22">Leuppi J</searchLink>; University Institute of Internal Medicine, Cantonal Hospital Baselland, Liestal, Switzerland; Faculty of Medicine, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gemicioglu+B%22">Gemicioglu B</searchLink>; Department of Pulmonary Diseases, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Celik+G%22">Celik G</searchLink>; Division of Immunology and Allergy, Ankara University School of Medicine, Ankara, Türkiye.<br /><searchLink fieldCode="AU" term="%22Damadoglu+E%22">Damadoglu E</searchLink>; Department of Pulmonary Diseases, Division of Allergy and Clinical Immunology, Hacettepe University, Faculty of Medicine, Ankara, Türkiye.<br /><searchLink fieldCode="AU" term="%22Goksel+O%22">Goksel O</searchLink>; Department of Pulmonary Medicine, Head Division of Immunology and Allergy, Laboratory of Occupational and Environmental Respiratory Diseases and Asthma, Ege University, Faculty of Medicine, Izmir, Türkiye; EgeSAM-Ege University Translational Pulmonary Research Center, Izmir, Türkiye.<br /><searchLink fieldCode="AU" term="%22Heaney+L%22">Heaney L</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Busby+J%22">Busby J</searchLink>; Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Redmond+C%22">Redmond C</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Masoli+M%22">Masoli M</searchLink>; Respiratory Medicine, Royal Devon University Healthcare NHS Foundation, Exeter, UK.<br /><searchLink fieldCode="AU" term="%22Chaudhuri+R%22">Chaudhuri R</searchLink>; Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK; School of Infection and Immunity, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Dennison+P%22">Dennison P</searchLink>; Respiratory Medicine, University Hospital Southampton NHS Foundation Trust, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Doe+S%22">Doe S</searchLink>; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Kurukulaaratchy+R%22">Kurukulaaratchy R</searchLink>; Respiratory Medicine, University Hospital Southampton NHS Foundation Trust, Southampton, UK; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre at University Hospital Southampton NHS Foundation Trust, Southampton, UK; The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, UK.<br /><searchLink fieldCode="AU" term="%22Bel+E%22">Bel E</searchLink>; Department of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Djukanovic+R%22">Djukanovic R</searchLink>; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre at University Hospital Southampton NHS Foundation Trust, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Bourdin+A%22">Bourdin A</searchLink>; PhyMedExp, (INSERM U 1046, CNRS UMR9214), Montpellier University, Montpellier, France; Department of Respiratory Diseases, Montpellier University Hospital, Arnaud de Villeneuve Hospital, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Ten+Brinke+A%22">Ten Brinke A</searchLink>; Department of Pulmonology, Frisius Medical Center, Leeuwarden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Schleich+F%22">Schleich F</searchLink>; Department of Pneumology-Allergology, CHU of Liège, Liége, Belgium; GIGAI(3), Pneumology Research Group, Liège University, Liège, Belgium; Exercise Physiology Lab, Department of Physical Activity and Rehabilitation Sciences, University of Liège, Liège, Belgium.<br /><searchLink fieldCode="AU" term="%22Porsbjerg+C%22">Porsbjerg C</searchLink>; Department of Respiratory Medicine and Infectious Diseases - Bispebjerg, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Bossios+A%22">Bossios A</searchLink>; Division for Lung and Airway Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Lung Laboratory, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; Karolinska Severe Asthma Center, Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden. Electronic address: apostolos.bossios@ki.se.
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  Data: <searchLink fieldCode="JN" term="%22101605555%22">The Lancet. Respiratory medicine</searchLink> [Lancet Respir Med] 2026 Jun 24. <i>Date of Electronic Publication: </i>2026 Jun 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101605555 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2213-2619 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222132600%22">22132600 </searchLink><i>NLM ISO Abbreviation: </i>Lancet Respir Med <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42341792
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        Value: 10.1016/S2213-2600(26)00141-4
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        Text: English
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      – TitleFull: Severe asthma and remission prospects in Europe (SHARP): insights from a multicentre observational study based on the European Severe Asthma Registry.
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            – D: 24
              M: 06
              Text: 2026 Jun 24
              Type: published
              Y: 2026
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            – TitleFull: The Lancet. Respiratory medicine
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