Mesenchymal stem cell secretome attenuates disease-associated microglial activation and cognitive decline in TBI-associated neuroinflammation.

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Title: Mesenchymal stem cell secretome attenuates disease-associated microglial activation and cognitive decline in TBI-associated neuroinflammation.
Authors: Rasiah PK; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: pk.rasiah@vanderbilt.edu., Ismael S; Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: sismael@tulane.edu., Elshaer S; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt. Electronic address: dr_s_elshaer@mans.edu.eg., Awad AM; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt. Electronic address: ahmedawad@mans.edu.eg., Salman M; Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: drsalmanmohd@gmail.com., Wang Z; Department of Pharmacology, Addiction Science and Toxicology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: zwang138@uthsc.edu., Cho H; University of Tennessee-Campbell Clinic Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, TN, 38104, USA; VA Medical Center, Memphis, TN, 38104, USA. Electronic address: hcho4@uthsc.edu., Bajpai AK; Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: akhil.bajpai@gmail.com., Liao FF; Department of Pharmacology, Addiction Science and Toxicology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: fliao@uthsc.edu., Lu L; Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: llu@uthsc.edu., Pentecost M; Diadem Biotherapeutics Inc, 370 Amapola Ave. Suite 100/101, Torrance, CA, 90501, USA. Electronic address: mickey@diadembio.com., Ishrat T; Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: tishrat@uthsc.edu., Gangaraju R; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA; Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: sgangara@uthsc.edu.
Source: Neurochemistry international [Neurochem Int] 2026 Sep; Vol. 198, pp. 106210. Date of Electronic Publication: 2026 Jun 24.
Publication Type: Journal Article
Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 8006959 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9754 (Electronic) Linking ISSN: 01970186 NLM ISO Abbreviation: Neurochem Int Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1872-9754
DOI:10.1016/j.neuint.2026.106210