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Mesenchymal stem cell secretome attenuates disease-associated microglial activation and cognitive decline in TBI-associated neuroinflammation.

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Title: Mesenchymal stem cell secretome attenuates disease-associated microglial activation and cognitive decline in TBI-associated neuroinflammation.
Authors: Rasiah PK; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: pk.rasiah@vanderbilt.edu., Ismael S; Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: sismael@tulane.edu., Elshaer S; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt. Electronic address: dr_s_elshaer@mans.edu.eg., Awad AM; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt. Electronic address: ahmedawad@mans.edu.eg., Salman M; Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: drsalmanmohd@gmail.com., Wang Z; Department of Pharmacology, Addiction Science and Toxicology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: zwang138@uthsc.edu., Cho H; University of Tennessee-Campbell Clinic Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, TN, 38104, USA; VA Medical Center, Memphis, TN, 38104, USA. Electronic address: hcho4@uthsc.edu., Bajpai AK; Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: akhil.bajpai@gmail.com., Liao FF; Department of Pharmacology, Addiction Science and Toxicology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: fliao@uthsc.edu., Lu L; Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: llu@uthsc.edu., Pentecost M; Diadem Biotherapeutics Inc, 370 Amapola Ave. Suite 100/101, Torrance, CA, 90501, USA. Electronic address: mickey@diadembio.com., Ishrat T; Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: tishrat@uthsc.edu., Gangaraju R; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA; Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: sgangara@uthsc.edu.
Source: Neurochemistry international [Neurochem Int] 2026 Sep; Vol. 198, pp. 106210. Date of Electronic Publication: 2026 Jun 24.
Publication Type: Journal Article
Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 8006959 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9754 (Electronic) Linking ISSN: 01970186 NLM ISO Abbreviation: Neurochem Int Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Mesenchymal stem cell secretome attenuates disease-associated microglial activation and cognitive decline in TBI-associated neuroinflammation.
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  Data: <searchLink fieldCode="AU" term="%22Rasiah+PK%22">Rasiah PK</searchLink>; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: pk.rasiah@vanderbilt.edu.<br /><searchLink fieldCode="AU" term="%22Ismael+S%22">Ismael S</searchLink>; Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: sismael@tulane.edu.<br /><searchLink fieldCode="AU" term="%22Elshaer+S%22">Elshaer S</searchLink>; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt. Electronic address: dr_s_elshaer@mans.edu.eg.<br /><searchLink fieldCode="AU" term="%22Awad+AM%22">Awad AM</searchLink>; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt. Electronic address: ahmedawad@mans.edu.eg.<br /><searchLink fieldCode="AU" term="%22Salman+M%22">Salman M</searchLink>; Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: drsalmanmohd@gmail.com.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Pharmacology, Addiction Science and Toxicology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: zwang138@uthsc.edu.<br /><searchLink fieldCode="AU" term="%22Cho+H%22">Cho H</searchLink>; University of Tennessee-Campbell Clinic Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, TN, 38104, USA; VA Medical Center, Memphis, TN, 38104, USA. Electronic address: hcho4@uthsc.edu.<br /><searchLink fieldCode="AU" term="%22Bajpai+AK%22">Bajpai AK</searchLink>; Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: akhil.bajpai@gmail.com.<br /><searchLink fieldCode="AU" term="%22Liao+FF%22">Liao FF</searchLink>; Department of Pharmacology, Addiction Science and Toxicology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: fliao@uthsc.edu.<br /><searchLink fieldCode="AU" term="%22Lu+L%22">Lu L</searchLink>; Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: llu@uthsc.edu.<br /><searchLink fieldCode="AU" term="%22Pentecost+M%22">Pentecost M</searchLink>; Diadem Biotherapeutics Inc, 370 Amapola Ave. Suite 100/101, Torrance, CA, 90501, USA. Electronic address: mickey@diadembio.com.<br /><searchLink fieldCode="AU" term="%22Ishrat+T%22">Ishrat T</searchLink>; Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: tishrat@uthsc.edu.<br /><searchLink fieldCode="AU" term="%22Gangaraju+R%22">Gangaraju R</searchLink>; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA; Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. Electronic address: sgangara@uthsc.edu.
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  Data: <searchLink fieldCode="JN" term="%228006959%22">Neurochemistry international</searchLink> [Neurochem Int] 2026 Sep; Vol. 198, pp. 106210. <i>Date of Electronic Publication: </i>2026 Jun 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Pergamon+Press%22">Pergamon Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8006959 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-9754 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201970186%22">01970186 </searchLink><i>NLM ISO Abbreviation: </i>Neurochem Int <i>Subsets: </i>MEDLINE
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