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Airway immune signatures of protection and disease progression in recent human tuberculosis household contacts.

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Title: Airway immune signatures of protection and disease progression in recent human tuberculosis household contacts.
Authors: Branchett WJ; Immunoregulation and Infection Laboratory, The Francis Crick Institute, London, UK., Kim JW; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Respiratory Department, University Hospitals of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Shields J; Immunoregulation and Infection Laboratory, The Francis Crick Institute, London, UK., Chakravarty P; Bioinformatics and Biostatistics Science Technology Platform, The Francis Crick Institute, London, UK., Lee J; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Respiratory Department, University Hospitals of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Novsarka I; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Respiratory Department, University Hospitals of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Slawinski H; Genomics Science Technology Platform, The Francis Crick Institute, London, UK., Wilkinson KA; Tuberculosis Laboratory, The Francis Crick Institute, London, UK., Wilkinson RJ; Tuberculosis Laboratory, The Francis Crick Institute, London, UK.; Department of Infectious Disease, Imperial College London, London, UK.; Wellcome Discovery Research Platforms in Infection, Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town, Cape Town, Republic of South Africa., Kamil A; Nuclear Medicine Department, University Hospitals of Leicester, Glenfield Hospital, Leicester, UK., Verma R; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Respiratory Department, University Hospitals of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Haldar P; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Respiratory Department, University Hospitals of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., O'Garra A; Immunoregulation and Infection Laboratory, The Francis Crick Institute, London, UK. anne.ogarra@crick.ac.uk.
Source: Nature immunology [Nat Immunol] 2026 Jun 24. Date of Electronic Publication: 2026 Jun 24.
Publication Type: Journal Article
Journal Info: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Branchett+WJ%22">Branchett WJ</searchLink>; Immunoregulation and Infection Laboratory, The Francis Crick Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Kim+JW%22">Kim JW</searchLink>; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Respiratory Department, University Hospitals of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Shields+J%22">Shields J</searchLink>; Immunoregulation and Infection Laboratory, The Francis Crick Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Chakravarty+P%22">Chakravarty P</searchLink>; Bioinformatics and Biostatistics Science Technology Platform, The Francis Crick Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Respiratory Department, University Hospitals of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Novsarka+I%22">Novsarka I</searchLink>; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Respiratory Department, University Hospitals of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Slawinski+H%22">Slawinski H</searchLink>; Genomics Science Technology Platform, The Francis Crick Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Wilkinson+KA%22">Wilkinson KA</searchLink>; Tuberculosis Laboratory, The Francis Crick Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Wilkinson+RJ%22">Wilkinson RJ</searchLink>; Tuberculosis Laboratory, The Francis Crick Institute, London, UK.; Department of Infectious Disease, Imperial College London, London, UK.; Wellcome Discovery Research Platforms in Infection, Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town, Cape Town, Republic of South Africa.<br /><searchLink fieldCode="AU" term="%22Kamil+A%22">Kamil A</searchLink>; Nuclear Medicine Department, University Hospitals of Leicester, Glenfield Hospital, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Verma+R%22">Verma R</searchLink>; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Respiratory Department, University Hospitals of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Haldar+P%22">Haldar P</searchLink>; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Respiratory Department, University Hospitals of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22O'Garra+A%22">O'Garra A</searchLink>; Immunoregulation and Infection Laboratory, The Francis Crick Institute, London, UK. anne.ogarra@crick.ac.uk.
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