Epiblast diversification and blood formation in a human pregastrula.

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Title: Epiblast diversification and blood formation in a human pregastrula.
Authors: Xiao Z; State Key Laboratory of Experimental Hematology, School of Life Science, Beijing Institute of Technology, Beijing, China. xiaozy@bit.edu.cn., Gong Y; State Key Laboratory of Experimental Hematology, Haihe Laboratory of Cell Ecosystem, Senior Department of Hematology, Fifth Medical Center, Medical Innovation Research Department, Chinese PLA General Hospital, Beijing, China.; State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, China., Yang X; State Key Laboratory of Experimental Hematology, School of Life Science, Beijing Institute of Technology, Beijing, China., He N; Department of Gynecology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Wang X; State Key Laboratory of Experimental Hematology, School of Life Science, Beijing Institute of Technology, Beijing, China., You G; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China., Zhu H; State Key Laboratory of Experimental Hematology, School of Life Science, Beijing Institute of Technology, Beijing, China., Liang Y; State Key Laboratory of Experimental Hematology, School of Life Science, Beijing Institute of Technology, Beijing, China., Xie X; State Key Laboratory of Experimental Hematology, School of Life Science, Beijing Institute of Technology, Beijing, China., Fang B; State Key Laboratory of Experimental Hematology, School of Life Science, Beijing Institute of Technology, Beijing, China., Liu G; Department of Medical Genetics, College of Basic Medical Science, Army Medical University (Third Military Medical University), Chongqing, China., Liu B; State Key Laboratory of Experimental Hematology, Haihe Laboratory of Cell Ecosystem, Senior Department of Hematology, Fifth Medical Center, Medical Innovation Research Department, Chinese PLA General Hospital, Beijing, China. bingliu17@126.com.; State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, China. bingliu17@126.com.; Department of Physiology and Pathophysiology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China. bingliu17@126.com., Lan Y; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China. lanyu@ihcams.ac.cn.; Tianjin Institutes of Health Science, Tianjin, China. lanyu@ihcams.ac.cn.
Source: Nature [Nature] 2026 Jun 24. Date of Electronic Publication: 2026 Jun 24.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: Epiblast diversification and blood formation in a human pregastrula.
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  Data: <searchLink fieldCode="AU" term="%22Xiao+Z%22">Xiao Z</searchLink>; State Key Laboratory of Experimental Hematology, School of Life Science, Beijing Institute of Technology, Beijing, China. xiaozy@bit.edu.cn.<br /><searchLink fieldCode="AU" term="%22Gong+Y%22">Gong Y</searchLink>; State Key Laboratory of Experimental Hematology, Haihe Laboratory of Cell Ecosystem, Senior Department of Hematology, Fifth Medical Center, Medical Innovation Research Department, Chinese PLA General Hospital, Beijing, China.; State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; State Key Laboratory of Experimental Hematology, School of Life Science, Beijing Institute of Technology, Beijing, China.<br /><searchLink fieldCode="AU" term="%22He+N%22">He N</searchLink>; Department of Gynecology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; State Key Laboratory of Experimental Hematology, School of Life Science, Beijing Institute of Technology, Beijing, China.<br /><searchLink fieldCode="AU" term="%22You+G%22">You G</searchLink>; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Zhu+H%22">Zhu H</searchLink>; State Key Laboratory of Experimental Hematology, School of Life Science, Beijing Institute of Technology, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Liang+Y%22">Liang Y</searchLink>; State Key Laboratory of Experimental Hematology, School of Life Science, Beijing Institute of Technology, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Xie+X%22">Xie X</searchLink>; State Key Laboratory of Experimental Hematology, School of Life Science, Beijing Institute of Technology, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Fang+B%22">Fang B</searchLink>; State Key Laboratory of Experimental Hematology, School of Life Science, Beijing Institute of Technology, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Liu+G%22">Liu G</searchLink>; Department of Medical Genetics, College of Basic Medical Science, Army Medical University (Third Military Medical University), Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Liu+B%22">Liu B</searchLink>; State Key Laboratory of Experimental Hematology, Haihe Laboratory of Cell Ecosystem, Senior Department of Hematology, Fifth Medical Center, Medical Innovation Research Department, Chinese PLA General Hospital, Beijing, China. bingliu17@126.com.; State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, China. bingliu17@126.com.; Department of Physiology and Pathophysiology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China. bingliu17@126.com.<br /><searchLink fieldCode="AU" term="%22Lan+Y%22">Lan Y</searchLink>; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China. lanyu@ihcams.ac.cn.; Tianjin Institutes of Health Science, Tianjin, China. lanyu@ihcams.ac.cn.
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        Value: 10.1038/s41586-026-10698-y
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            – D: 24
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              Text: 2026 Jun 24
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