Persistent interferon signaling and clonal expansion mark early events in DNA methylation damage-induced liver cancer.

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Title: Persistent interferon signaling and clonal expansion mark early events in DNA methylation damage-induced liver cancer.
Authors: Pribyl LJ; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States., Kay JE; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.; Silent Spring Institute, Newton, MA 02460, United States., Corrigan JJ; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States., Volk LB; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States., Norales M; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States., Owiti NA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States., Kowal EA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States., Kohale IN; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States., Nazari IS; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States., Swanson MR; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States., Moise AC; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States., Ma D; David H. Koch Institute for Integrative Cancer Research, Bioinformatics and Computing Facility of Swanson Biotechnology Center, Massachusetts Institute of Technology, Cambridge, MA 02139, United States., Levine SS; BioMicro Center, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, United States., Michelsen EM; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, United States., Croy RG; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, United States., Ragan T; TissueVision, Inc., Newton, MA 02458, United States., Torous DK; Litron Laboratories, Rochester, NY 14623, United States., Avlasevich SL; Litron Laboratories, Rochester, NY 14623, United States., Dertinger SD; Litron Laboratories, Rochester, NY 14623, United States., Carrasco SE; Laboratory of Comparative Pathology, Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center and Rockefeller University, New York, NY 10065, United States., Samson LD; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, United States., Essigmann JM; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, United States., White FM; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States., Engelward BP; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.
Source: NAR cancer [NAR Cancer] 2026 Jun 23; Vol. 8 (2), pp. zcag014. Date of Electronic Publication: 2026 Jun 23 (Print Publication: 2026).
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101769553 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-8674 (Electronic) Linking ISSN: 26328674 NLM ISO Abbreviation: NAR Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Persistent interferon signaling and clonal expansion mark early events in DNA methylation damage-induced liver cancer.
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  Data: <searchLink fieldCode="AU" term="%22Pribyl+LJ%22">Pribyl LJ</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.<br /><searchLink fieldCode="AU" term="%22Kay+JE%22">Kay JE</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.; Silent Spring Institute, Newton, MA 02460, United States.<br /><searchLink fieldCode="AU" term="%22Corrigan+JJ%22">Corrigan JJ</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.<br /><searchLink fieldCode="AU" term="%22Volk+LB%22">Volk LB</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.<br /><searchLink fieldCode="AU" term="%22Norales+M%22">Norales M</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.<br /><searchLink fieldCode="AU" term="%22Owiti+NA%22">Owiti NA</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.<br /><searchLink fieldCode="AU" term="%22Kowal+EA%22">Kowal EA</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.<br /><searchLink fieldCode="AU" term="%22Kohale+IN%22">Kohale IN</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.<br /><searchLink fieldCode="AU" term="%22Nazari+IS%22">Nazari IS</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.<br /><searchLink fieldCode="AU" term="%22Swanson+MR%22">Swanson MR</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.<br /><searchLink fieldCode="AU" term="%22Moise+AC%22">Moise AC</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.<br /><searchLink fieldCode="AU" term="%22Ma+D%22">Ma D</searchLink>; David H. Koch Institute for Integrative Cancer Research, Bioinformatics and Computing Facility of Swanson Biotechnology Center, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.<br /><searchLink fieldCode="AU" term="%22Levine+SS%22">Levine SS</searchLink>; BioMicro Center, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.<br /><searchLink fieldCode="AU" term="%22Michelsen+EM%22">Michelsen EM</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.<br /><searchLink fieldCode="AU" term="%22Croy+RG%22">Croy RG</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.<br /><searchLink fieldCode="AU" term="%22Ragan+T%22">Ragan T</searchLink>; TissueVision, Inc., Newton, MA 02458, United States.<br /><searchLink fieldCode="AU" term="%22Torous+DK%22">Torous DK</searchLink>; Litron Laboratories, Rochester, NY 14623, United States.<br /><searchLink fieldCode="AU" term="%22Avlasevich+SL%22">Avlasevich SL</searchLink>; Litron Laboratories, Rochester, NY 14623, United States.<br /><searchLink fieldCode="AU" term="%22Dertinger+SD%22">Dertinger SD</searchLink>; Litron Laboratories, Rochester, NY 14623, United States.<br /><searchLink fieldCode="AU" term="%22Carrasco+SE%22">Carrasco SE</searchLink>; Laboratory of Comparative Pathology, Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center and Rockefeller University, New York, NY 10065, United States.<br /><searchLink fieldCode="AU" term="%22Samson+LD%22">Samson LD</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.<br /><searchLink fieldCode="AU" term="%22Essigmann+JM%22">Essigmann JM</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.<br /><searchLink fieldCode="AU" term="%22White+FM%22">White FM</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.<br /><searchLink fieldCode="AU" term="%22Engelward+BP%22">Engelward BP</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.
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  Data: <searchLink fieldCode="JN" term="%22101769553%22">NAR cancer</searchLink> [NAR Cancer] 2026 Jun 23; Vol. 8 (2), pp. zcag014. <i>Date of Electronic Publication: </i>2026 Jun 23 (<i>Print Publication: </i>2026).
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