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Polystyrene nanoplastics impair epithelial barrier establishment and modulate extracellular vesicle release in human bronchial cells cultured at the air-liquid interface.

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Title: Polystyrene nanoplastics impair epithelial barrier establishment and modulate extracellular vesicle release in human bronchial cells cultured at the air-liquid interface.
Authors: Milillo C; Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy; Department of Innovative Technologies in Medicine & Dentistry, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy., Bruno A; Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy; Department of Innovative Technologies in Medicine & Dentistry, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy., D'Ascanio F; Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy; Department of Medicine and Aging Sciences, 'G.d'Annunzio' University of Chieti-Pescara, Chieti, Italy; Department of Humanities, Law and Economics, 'Leonardo da Vinci' University, Torrevecchia Teatina 66010, Italy., Gatta M; Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy; Department of Innovative Technologies in Medicine & Dentistry, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy., Battistelli M; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino 61029, Italy., Burattini S; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino 61029, Italy., Di Carlo P; Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy; Department of Innovative Technologies in Medicine & Dentistry, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy., Parrón-Ballesteros J; Department of Biochemistry and Molecular Biology, Faculty of Chemistry, Complutense University of Madrid, Madrid, Spain., Niccolai E; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Dovizio M; Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy; Department of Innovative Technologies in Medicine & Dentistry, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy. Electronic address: m.dovizio@unich.it., Lanuti P; Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy; Department of Medicine and Aging Sciences, 'G.d'Annunzio' University of Chieti-Pescara, Chieti, Italy., Batanero E; Department of Biochemistry and Molecular Biology, Faculty of Chemistry, Complutense University of Madrid, Madrid, Spain., Amedei A; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Ballerini P; Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy; Department of Innovative Technologies in Medicine & Dentistry, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.
Source: Toxicology [Toxicology] 2026 Jun 25; Vol. 526, pp. 154533. Date of Electronic Publication: 2026 Jun 25.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0361055 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3185 (Electronic) Linking ISSN: 0300483X NLM ISO Abbreviation: Toxicology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-3185
DOI:10.1016/j.tox.2026.154533