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Genetic and Environmental Effects on BMI Fluctuation Across the Adult Life Course and Its Associations With Baseline BMI and BMI Change: An Individual-Based Study of 14 Longitudinal Twin Cohorts.

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Title: Genetic and Environmental Effects on BMI Fluctuation Across the Adult Life Course and Its Associations With Baseline BMI and BMI Change: An Individual-Based Study of 14 Longitudinal Twin Cohorts.
Authors: Obeso Fernandez A; Helsinki Institute for Demography and Population Health, University of Helsinki, Helsinki, Finland.; Department of Genetics, Physical Anthropology and Animal Physiology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Bilbao, Spain., Eriksson A; cGEM, Institute of Genomics, University of Tartu, Tartu, Estonia., Drouard G; Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland., Jelenkovic A; Department of Genetics, Physical Anthropology and Animal Physiology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Bilbao, Spain., Aaltonen S; Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland.; Clinicum, Department of Psychiatry, University of Helsinki, Helsinki, Finland., Ollikainen M; Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Spector T; Department of Twin Research and Genetic Epidemiology, King's College, London, UK., Mangino M; Department of Twin Research and Genetic Epidemiology, King's College, London, UK., Christensen K; The Danish Twin Registry, Institute of Public Health, Epidemiology, Biostatistics & Biodemography, University of Southern Denmark, Odense, Denmark., Skytthe A; The Danish Twin Registry, Institute of Public Health, Epidemiology, Biostatistics & Biodemography, University of Southern Denmark, Odense, Denmark., Kyvik KO; Research Unit of Clinical Genetics, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Odense University Hospital, Odense, Denmark., Medda E; Centre for Behavioural Sciences and Mental Health, Istituto Superiore di Sanità, Rome, Italy., Fagnani C; Centre for Behavioural Sciences and Mental Health, Istituto Superiore di Sanità, Rome, Italy., Corley RP; Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado, USA., Huibregtse BM; Department of Psychology and Neuroscience, University of Colorado, Boulder, Colorado, USA., Toccaceli V; Centre for Behavioural Sciences and Mental Health, Istituto Superiore di Sanità, Rome, Italy., Rasmussen FE; Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden., Tynelius P; Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden., Medland SE; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Gordon SD; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Duncan GE; Washington State Twin Registry, Washington State University-Health Sciences Spokane, Spokane, Washington, USA., Buchwald D; Washington State Twin Registry, University of Washington, Seattle, Washington, USA., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Karlsson IK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Dahl Aslan AK; School of Health Sciences, University of Skövde, Skövde, Sweden., Bartels M; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Ligthart L; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., de Geus EJC; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Gatz M; Center for Economic and Social Research, University of Southern California, Los Angeles, California, USA., Butler DA; Health and Medicine Division, the National Academies of Sciences, Engineering, and Medicine, Washington, DC, USA., Pyun H; Department of Epidemiology, Seoul National University School of Public Health, Seoul, Korea., Kim J; Institute of Health & Environmental, Seoul National University, Seoul, Korea., Lee SJ; Institute of Health & Environmental, Seoul National University, Seoul, Korea., Sung J; Department of Epidemiology, Seoul National University School of Public Health, Seoul, Korea.; Institute of Health & Environmental, Seoul National University, Seoul, Korea., Bruins S; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Pool R; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Boomsma DI; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.; Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, the Netherlands., Kaprio J; Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland., Silventoinen K; Helsinki Institute for Demography and Population Health, University of Helsinki, Helsinki, Finland.
Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2026 Jun 25. Date of Electronic Publication: 2026 Jun 25.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Genetic and Environmental Effects on BMI Fluctuation Across the Adult Life Course and Its Associations With Baseline BMI and BMI Change: An Individual-Based Study of 14 Longitudinal Twin Cohorts.
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  Data: <searchLink fieldCode="AU" term="%22Obeso+Fernandez+A%22">Obeso Fernandez A</searchLink>; Helsinki Institute for Demography and Population Health, University of Helsinki, Helsinki, Finland.; Department of Genetics, Physical Anthropology and Animal Physiology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Bilbao, Spain.<br /><searchLink fieldCode="AU" term="%22Eriksson+A%22">Eriksson A</searchLink>; cGEM, Institute of Genomics, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Drouard+G%22">Drouard G</searchLink>; Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Jelenkovic+A%22">Jelenkovic A</searchLink>; Department of Genetics, Physical Anthropology and Animal Physiology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Bilbao, Spain.<br /><searchLink fieldCode="AU" term="%22Aaltonen+S%22">Aaltonen S</searchLink>; Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland.; Clinicum, Department of Psychiatry, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Ollikainen+M%22">Ollikainen M</searchLink>; Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Spector+T%22">Spector T</searchLink>; Department of Twin Research and Genetic Epidemiology, King's College, London, UK.<br /><searchLink fieldCode="AU" term="%22Mangino+M%22">Mangino M</searchLink>; Department of Twin Research and Genetic Epidemiology, King's College, London, UK.<br /><searchLink fieldCode="AU" term="%22Christensen+K%22">Christensen K</searchLink>; The Danish Twin Registry, Institute of Public Health, Epidemiology, Biostatistics & Biodemography, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Skytthe+A%22">Skytthe A</searchLink>; The Danish Twin Registry, Institute of Public Health, Epidemiology, Biostatistics & Biodemography, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Kyvik+KO%22">Kyvik KO</searchLink>; Research Unit of Clinical Genetics, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Odense University Hospital, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Medda+E%22">Medda E</searchLink>; Centre for Behavioural Sciences and Mental Health, Istituto Superiore di Sanità, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Fagnani+C%22">Fagnani C</searchLink>; Centre for Behavioural Sciences and Mental Health, Istituto Superiore di Sanità, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Corley+RP%22">Corley RP</searchLink>; Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Huibregtse+BM%22">Huibregtse BM</searchLink>; Department of Psychology and Neuroscience, University of Colorado, Boulder, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Toccaceli+V%22">Toccaceli V</searchLink>; 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Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Karlsson+IK%22">Karlsson IK</searchLink>; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Dahl+Aslan+AK%22">Dahl Aslan AK</searchLink>; School of Health Sciences, University of Skövde, Skövde, Sweden.<br /><searchLink fieldCode="AU" term="%22Bartels+M%22">Bartels M</searchLink>; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Ligthart+L%22">Ligthart L</searchLink>; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Geus+EJC%22">de Geus EJC</searchLink>; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Gatz+M%22">Gatz M</searchLink>; Center for Economic and Social Research, University of Southern California, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Butler+DA%22">Butler DA</searchLink>; Health and Medicine Division, the National Academies of Sciences, Engineering, and Medicine, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Pyun+H%22">Pyun H</searchLink>; Department of Epidemiology, Seoul National University School of Public Health, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Institute of Health & Environmental, Seoul National University, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SJ%22">Lee SJ</searchLink>; Institute of Health & Environmental, Seoul National University, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Sung+J%22">Sung J</searchLink>; Department of Epidemiology, Seoul National University School of Public Health, Seoul, Korea.; Institute of Health & Environmental, Seoul National University, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Bruins+S%22">Bruins S</searchLink>; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Pool+R%22">Pool R</searchLink>; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Martin+NG%22">Martin NG</searchLink>; QIMR Berghofer Medical Research Institute, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Boomsma+DI%22">Boomsma DI</searchLink>; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.; Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Kaprio+J%22">Kaprio J</searchLink>; Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Silventoinen+K%22">Silventoinen K</searchLink>; Helsinki Institute for Demography and Population Health, University of Helsinki, Helsinki, Finland.
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  Data: <searchLink fieldCode="JN" term="%22100883645%22">Diabetes, obesity & metabolism</searchLink> [Diabetes Obes Metab] 2026 Jun 25. <i>Date of Electronic Publication: </i>2026 Jun 25.
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