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Hypoattenuated Leaflet Thickening After TAVR: Incidence, Predictors, and the Role of Platelet Reactivity: A Prospective Multicenter Observational Study.

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Title: Hypoattenuated Leaflet Thickening After TAVR: Incidence, Predictors, and the Role of Platelet Reactivity: A Prospective Multicenter Observational Study.
Authors: Jimenez-Quevedo P; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Espejo-Paeres C; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Spione F; Cardiology Department, University Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain., Hennessey B; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., McInerney A; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Marroquin L; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Bernardo E; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Ortega-Pozzi MA; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Tirado-Conte G; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Macaya F; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Cabeza B; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Martín Lores I; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Salinas P; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Nuñez-Gil I; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Mejía-Rentería H; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Fernández-Ortiz A; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Gómez De Diego JJ; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Perez-Villacastin J; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Escaned J; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Bustos A; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Sabate M; Cardiology Department, University Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain., Agustin Loeches A; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Gonzalo N; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Nombela-Franco L; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain., Regueiro A; Cardiology Department, University Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain., Pozo Osinalde E; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
Source: Journal of clinical medicine [J Clin Med] 2026 Jun 09; Vol. 15 (12). Date of Electronic Publication: 2026 Jun 09.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101606588 Publication Model: Electronic Cited Medium: Print ISSN: 2077-0383 (Print) Linking ISSN: 20770383 NLM ISO Abbreviation: J Clin Med Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Hypoattenuated Leaflet Thickening After TAVR: Incidence, Predictors, and the Role of Platelet Reactivity: A Prospective Multicenter Observational Study.
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  Data: <searchLink fieldCode="AU" term="%22Jimenez-Quevedo+P%22">Jimenez-Quevedo P</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Espejo-Paeres+C%22">Espejo-Paeres C</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Spione+F%22">Spione F</searchLink>; Cardiology Department, University Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Hennessey+B%22">Hennessey B</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22McInerney+A%22">McInerney A</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Marroquin+L%22">Marroquin L</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Bernardo+E%22">Bernardo E</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Ortega-Pozzi+MA%22">Ortega-Pozzi MA</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Tirado-Conte+G%22">Tirado-Conte G</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Macaya+F%22">Macaya F</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Cabeza+B%22">Cabeza B</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Martín+Lores+I%22">Martín Lores I</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Salinas+P%22">Salinas P</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Nuñez-Gil+I%22">Nuñez-Gil I</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Mejía-Rentería+H%22">Mejía-Rentería H</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Fernández-Ortiz+A%22">Fernández-Ortiz A</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Gómez+De+Diego+JJ%22">Gómez De Diego JJ</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Perez-Villacastin+J%22">Perez-Villacastin J</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Escaned+J%22">Escaned J</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Bustos+A%22">Bustos A</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Sabate+M%22">Sabate M</searchLink>; Cardiology Department, University Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Agustin+Loeches+A%22">Agustin Loeches A</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Gonzalo+N%22">Gonzalo N</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Nombela-Franco+L%22">Nombela-Franco L</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Regueiro+A%22">Regueiro A</searchLink>; Cardiology Department, University Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Pozo+Osinalde+E%22">Pozo Osinalde E</searchLink>; Cardiology Department, Clinico San Carlos University Hospital, Health Research Institute of Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
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