Coumarins Disrupt Cell-Cell Communication and Virulence in Priority Pathogens: Targeting the PQS Signalling System in Pseudomonas aeruginosa.

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Title: Coumarins Disrupt Cell-Cell Communication and Virulence in Priority Pathogens: Targeting the PQS Signalling System in Pseudomonas aeruginosa.
Authors: Boon D; School of Microbiology, University College Cork, Cork, Ireland., O'Rourke B; School of Microbiology, University College Cork, Cork, Ireland., Carmody M; School of Microbiology, University College Cork, Cork, Ireland.; School of Chemistry and Analytical & Biological Chemistry Research Facility (ABCRF), University College Cork, Ireland., Woods DF; School of Microbiology, University College Cork, Cork, Ireland., Gloe A; School of Microbiology, University College Cork, Cork, Ireland.; Institute for Pharmaceutical Microbiology, University of Bonn, Bonn, Germany., Platero-Rochart D; Laboratory of Computer-Aided Molecular Design, Division of Medicinal Chemistry, Otto-Loewi Research Center, Medical University of Graz, Graz, Austria., Sánchez-Murcia PA; Laboratory of Computer-Aided Molecular Design, Division of Medicinal Chemistry, Otto-Loewi Research Center, Medical University of Graz, Graz, Austria.; BioTechMed-Graz, Graz, Austria., McGlacken GP; School of Chemistry and Analytical & Biological Chemistry Research Facility (ABCRF), University College Cork, Ireland.; SSPC, The Research Ireland Centre for Pharmaceuticals, Ireland., Reen FJ; School of Microbiology, University College Cork, Cork, Ireland.; SSPC, The Research Ireland Centre for Pharmaceuticals, Ireland.
Source: Microbial biotechnology [Microb Biotechnol] 2026 Jul; Vol. 19 (7), pp. e70404.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101316335 Publication Model: Print Cited Medium: Internet ISSN: 1751-7915 (Electronic) Linking ISSN: 17517915 NLM ISO Abbreviation: Microb Biotechnol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1751-7915
DOI:10.1111/1751-7915.70404