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Randomized, double-blind, sham-controlled trial of an intraoral photobiomodulation device for oral mucositis and associated complications due to radiotherapy for head and neck cancer.

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Title: Randomized, double-blind, sham-controlled trial of an intraoral photobiomodulation device for oral mucositis and associated complications due to radiotherapy for head and neck cancer.
Authors: Hu K; Department of Radiation Oncology and Department of Otolaryngology-Head and Neck Surgery, New York University, New York, NY, USA. kenneth.hu@nyulangone.org., Shah P; St. Elizabeth Healthcare, Edgewood, KY, USA., Nguyen MC; Oklahoma Cancer Specialists and Research Institute, Tulsa, OK, USA., McCluskey C; Christ Hospital, Cincinnati, OH, USA., Kane A; University of Mississippi Medical Center, Jackson, MS, USA.; University of Alabama at Birmingham, Birmingham, AL, USA., Ove R; MetroHealth, Case Western Reserve University, Cleveland, OH, USA., Willey CD; University of Alabama at Birmingham, Birmingham, AL, USA., Katz S; Willis-Knighton Cancer Center, Shreveport, LA, USA., Marathe O; The Oncology Institute of Hope and Innovation, Long Beach, CA, USA., Valentin S; The Ohio State University, Columbus, OH, USA., Frustino J; Erie County Medical Center, Buffalo, NY, USA., Villa A; Miami Cancer Institute, Miami, FL, USA., Spencer S; University of Alabama at Birmingham, Birmingham, AL, USA., Holtzapfel C; St. Elizabeth Healthcare, Edgewood, KY, USA., Treister N; Brigham and Women's Hospital, Boston, MA, USA., Lalla RV; University of Connecticut Health, Farmington, CT, USA.
Source: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer [Support Care Cancer] 2026 Jun 26; Vol. 34 (7). Date of Electronic Publication: 2026 Jun 26.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 9302957 Publication Model: Electronic Cited Medium: Internet ISSN: 1433-7339 (Electronic) Linking ISSN: 09414355 NLM ISO Abbreviation: Support Care Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Randomized, double-blind, sham-controlled trial of an intraoral photobiomodulation device for oral mucositis and associated complications due to radiotherapy for head and neck cancer.
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  Data: <searchLink fieldCode="AU" term="%22Hu+K%22">Hu K</searchLink>; Department of Radiation Oncology and Department of Otolaryngology-Head and Neck Surgery, New York University, New York, NY, USA. kenneth.hu@nyulangone.org.<br /><searchLink fieldCode="AU" term="%22Shah+P%22">Shah P</searchLink>; St. Elizabeth Healthcare, Edgewood, KY, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+MC%22">Nguyen MC</searchLink>; Oklahoma Cancer Specialists and Research Institute, Tulsa, OK, USA.<br /><searchLink fieldCode="AU" term="%22McCluskey+C%22">McCluskey C</searchLink>; Christ Hospital, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Kane+A%22">Kane A</searchLink>; University of Mississippi Medical Center, Jackson, MS, USA.; University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Ove+R%22">Ove R</searchLink>; MetroHealth, Case Western Reserve University, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Willey+CD%22">Willey CD</searchLink>; University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Katz+S%22">Katz S</searchLink>; Willis-Knighton Cancer Center, Shreveport, LA, USA.<br /><searchLink fieldCode="AU" term="%22Marathe+O%22">Marathe O</searchLink>; The Oncology Institute of Hope and Innovation, Long Beach, CA, USA.<br /><searchLink fieldCode="AU" term="%22Valentin+S%22">Valentin S</searchLink>; The Ohio State University, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Frustino+J%22">Frustino J</searchLink>; Erie County Medical Center, Buffalo, NY, USA.<br /><searchLink fieldCode="AU" term="%22Villa+A%22">Villa A</searchLink>; Miami Cancer Institute, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Spencer+S%22">Spencer S</searchLink>; University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Holtzapfel+C%22">Holtzapfel C</searchLink>; St. Elizabeth Healthcare, Edgewood, KY, USA.<br /><searchLink fieldCode="AU" term="%22Treister+N%22">Treister N</searchLink>; Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lalla+RV%22">Lalla RV</searchLink>; University of Connecticut Health, Farmington, CT, USA.
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  Data: <searchLink fieldCode="JN" term="%229302957%22">Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer</searchLink> [Support Care Cancer] 2026 Jun 26; Vol. 34 (7). <i>Date of Electronic Publication: </i>2026 Jun 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+International%22">Springer International </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>9302957 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1433-7339 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209414355%22">09414355 </searchLink><i>NLM ISO Abbreviation: </i>Support Care Cancer <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00520-026-10904-7
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        Text: English
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