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Heart Failure Medication Withdrawal in Patients With Improved Cardiac Function After Atrial Fibrillation Ablation: The DEFINITION-AF Pilot Randomized Clinical Trial.

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Title: Heart Failure Medication Withdrawal in Patients With Improved Cardiac Function After Atrial Fibrillation Ablation: The DEFINITION-AF Pilot Randomized Clinical Trial.
Authors: Li S; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Sun Y; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Lai Y; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Wang H; Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Han J; Maternal-Fetal Medicine Center in Fetal Heart Disease, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Zhang Y; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Gao M; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Wang J; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Zhang J; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., He L; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Cui J; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Guo X; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Zuo S; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Liu X; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Liu N; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Li S; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Zhou N; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Tang R; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Long D; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Sang C; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Du X; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Dong J; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Ma C; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Source: JAMA network open [JAMA Netw Open] 2026 Jun 01; Vol. 9 (6), pp. e2620145. Date of Electronic Publication: 2026 Jun 01.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101729235 Publication Model: Electronic Cited Medium: Internet ISSN: 2574-3805 (Electronic) Linking ISSN: 25743805 NLM ISO Abbreviation: JAMA Netw Open Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Heart Failure Medication Withdrawal in Patients With Improved Cardiac Function After Atrial Fibrillation Ablation: The DEFINITION-AF Pilot Randomized Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Lai+Y%22">Lai Y</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Han+J%22">Han J</searchLink>; Maternal-Fetal Medicine Center in Fetal Heart Disease, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Gao+M%22">Gao M</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22He+L%22">He L</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Cui+J%22">Cui J</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Guo+X%22">Guo X</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zuo+S%22">Zuo S</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Liu+N%22">Liu N</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhou+N%22">Zhou N</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Tang+R%22">Tang R</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Long+D%22">Long D</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Sang+C%22">Sang C</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Du+X%22">Du X</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Dong+J%22">Dong J</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Ma+C%22">Ma C</searchLink>; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
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  Data: <searchLink fieldCode="JN" term="%22101729235%22">JAMA network open</searchLink> [JAMA Netw Open] 2026 Jun 01; Vol. 9 (6), pp. e2620145. <i>Date of Electronic Publication: </i>2026 Jun 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Medical+Association%22">American Medical Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101729235 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2574-3805 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225743805%22">25743805 </searchLink><i>NLM ISO Abbreviation: </i>JAMA Netw Open <i>Subsets: </i>MEDLINE
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        Value: 10.1001/jamanetworkopen.2026.20145
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              Text: 2026 Jun 01
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