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AI-Based Pathology classifier Predicts Sensitivity to Enzalutamide in Metastatic Hormone-Sensitive Prostate Cancer: A Biomarker Analysis of the ENZAMET Trial.

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Title: AI-Based Pathology classifier Predicts Sensitivity to Enzalutamide in Metastatic Hormone-Sensitive Prostate Cancer: A Biomarker Analysis of the ENZAMET Trial.
Authors: Medina S; The Wallace H. Coulter Department of Biomedical Engineering Atlanta United States., Tokuyama N; Emory University Atlanta United States., Putcha V; The Wallace H. Coulter Department of Biomedical Engineering Atlanta United States., Pathak T; Emory University Atlanta, Georgia United States., Fu P; Case Western Reserve University Cleveland, Ohio United States., Thomas H; The University of Sydney Camperdown, NSW Australia., Subhash VV; Australian and New Zealand Urogenital and Prostate Cancer Trials Group Sydney, NSW Australia., Yip S; The University of Sydney Sydney, NSW Australia., Lin HM; Garvan Institute of Medical Research Darlinghurst, NSW Australia., Horvath LG; Chris O'Brien Lifehouse Sydney, New South Wales Australia., Kench JG; Royal Prince Alfred Hospital Camperdown, NSW Australia., Zhang A; The University of Sydney Sydney, NSW Australia., Stockler MR; The University of Sydney Sydney, NSW Australia., Joshua AM; The Kinghorn Cancer Centre Darlinghurst, NSW Australia., Azad A; Peter MacCallum Cancer Centre Melbourne Australia., Oakes SR; Australian and New Zealand Urogenital and Prostate Cancer Trials Group Australia., Davis ID; Monash University Box Hill, Victoria Australia., Sweeney CJ; Adelaide University Adelaide, SA Australia., Madabhushi A; Emory University Atlanta, GA United States.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2026 Jun 26. Date of Electronic Publication: 2026 Jun 26.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: AI-Based Pathology classifier Predicts Sensitivity to Enzalutamide in Metastatic Hormone-Sensitive Prostate Cancer: A Biomarker Analysis of the ENZAMET Trial.
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  Data: <searchLink fieldCode="AU" term="%22Medina+S%22">Medina S</searchLink>; The Wallace H. Coulter Department of Biomedical Engineering Atlanta United States.<br /><searchLink fieldCode="AU" term="%22Tokuyama+N%22">Tokuyama N</searchLink>; Emory University Atlanta United States.<br /><searchLink fieldCode="AU" term="%22Putcha+V%22">Putcha V</searchLink>; The Wallace H. Coulter Department of Biomedical Engineering Atlanta United States.<br /><searchLink fieldCode="AU" term="%22Pathak+T%22">Pathak T</searchLink>; Emory University Atlanta, Georgia United States.<br /><searchLink fieldCode="AU" term="%22Fu+P%22">Fu P</searchLink>; Case Western Reserve University Cleveland, Ohio United States.<br /><searchLink fieldCode="AU" term="%22Thomas+H%22">Thomas H</searchLink>; The University of Sydney Camperdown, NSW Australia.<br /><searchLink fieldCode="AU" term="%22Subhash+VV%22">Subhash VV</searchLink>; Australian and New Zealand Urogenital and Prostate Cancer Trials Group Sydney, NSW Australia.<br /><searchLink fieldCode="AU" term="%22Yip+S%22">Yip S</searchLink>; The University of Sydney Sydney, NSW Australia.<br /><searchLink fieldCode="AU" term="%22Lin+HM%22">Lin HM</searchLink>; Garvan Institute of Medical Research Darlinghurst, NSW Australia.<br /><searchLink fieldCode="AU" term="%22Horvath+LG%22">Horvath LG</searchLink>; Chris O'Brien Lifehouse Sydney, New South Wales Australia.<br /><searchLink fieldCode="AU" term="%22Kench+JG%22">Kench JG</searchLink>; Royal Prince Alfred Hospital Camperdown, NSW Australia.<br /><searchLink fieldCode="AU" term="%22Zhang+A%22">Zhang A</searchLink>; The University of Sydney Sydney, NSW Australia.<br /><searchLink fieldCode="AU" term="%22Stockler+MR%22">Stockler MR</searchLink>; The University of Sydney Sydney, NSW Australia.<br /><searchLink fieldCode="AU" term="%22Joshua+AM%22">Joshua AM</searchLink>; The Kinghorn Cancer Centre Darlinghurst, NSW Australia.<br /><searchLink fieldCode="AU" term="%22Azad+A%22">Azad A</searchLink>; Peter MacCallum Cancer Centre Melbourne Australia.<br /><searchLink fieldCode="AU" term="%22Oakes+SR%22">Oakes SR</searchLink>; Australian and New Zealand Urogenital and Prostate Cancer Trials Group Australia.<br /><searchLink fieldCode="AU" term="%22Davis+ID%22">Davis ID</searchLink>; Monash University Box Hill, Victoria Australia.<br /><searchLink fieldCode="AU" term="%22Sweeney+CJ%22">Sweeney CJ</searchLink>; Adelaide University Adelaide, SA Australia.<br /><searchLink fieldCode="AU" term="%22Madabhushi+A%22">Madabhushi A</searchLink>; Emory University Atlanta, GA United States.
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  Data: <searchLink fieldCode="JN" term="%229502500%22">Clinical cancer research : an official journal of the American Association for Cancer Research</searchLink> [Clin Cancer Res] 2026 Jun 26. <i>Date of Electronic Publication: </i>2026 Jun 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9502500 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-3265 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210780432%22">10780432 </searchLink><i>NLM ISO Abbreviation: </i>Clin Cancer Res <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun 26
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