Glucans from Lentinus edodes Inhibit Myeloid-Derived Suppressor Cell-Induced Regulatory T Cells via the TLR4-TAK1-JNK Signaling Pathway to Scavenge Reactive Oxygen Species.

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Title: Glucans from Lentinus edodes Inhibit Myeloid-Derived Suppressor Cell-Induced Regulatory T Cells via the TLR4-TAK1-JNK Signaling Pathway to Scavenge Reactive Oxygen Species.
Authors: Ma J; Department of Pathology, The affiliated Hospital, Southwest Medical University, Luzhou 646000, China.; Precision Pathology Diagnosis for Serious Diseases Key Laboratory of LuZhou, Luzhou 646000, China.; Department of Urology, The affiliated Hospital, Southwest Medical University, Luzhou 646000, China., Wang M; Tianjin Key Laboratory of Technologies Enabling Development of Clinical Therapeutics and Diagnosis, School of Pharmacy, Tianjin Medical University, Tianjin 300070, China., Jin Z; Luzhou City Hospital of Traditional Chinese Medicine, Luzhou 646000, China., Long X; Department of Pathology, The affiliated Hospital, Southwest Medical University, Luzhou 646000, China., Chen X; Tianjin Key Laboratory of Technologies Enabling Development of Clinical Therapeutics and Diagnosis, School of Pharmacy, Tianjin Medical University, Tianjin 300070, China., Yang Z; Department of Pathology, The affiliated Hospital, Southwest Medical University, Luzhou 646000, China., Dong C; Tianjin Key Laboratory of Technologies Enabling Development of Clinical Therapeutics and Diagnosis, School of Pharmacy, Tianjin Medical University, Tianjin 300070, China., Tao N; Department of Pathology, The affiliated Hospital, Southwest Medical University, Luzhou 646000, China.; Key Laboratory of Epigenetic Regulation and Intervention, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Source: Journal of agricultural and food chemistry [J Agric Food Chem] 2026 Jul 08; Vol. 74 (26), pp. 20430-20445. Date of Electronic Publication: 2026 Jun 26.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Glucans from Lentinus edodes Inhibit Myeloid-Derived Suppressor Cell-Induced Regulatory T Cells via the TLR4-TAK1-JNK Signaling Pathway to Scavenge Reactive Oxygen Species.
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  Data: <searchLink fieldCode="AU" term="%22Ma+J%22">Ma J</searchLink>; Department of Pathology, The affiliated Hospital, Southwest Medical University, Luzhou 646000, China.; Precision Pathology Diagnosis for Serious Diseases Key Laboratory of LuZhou, Luzhou 646000, China.; Department of Urology, The affiliated Hospital, Southwest Medical University, Luzhou 646000, China.<br /><searchLink fieldCode="AU" term="%22Wang+M%22">Wang M</searchLink>; Tianjin Key Laboratory of Technologies Enabling Development of Clinical Therapeutics and Diagnosis, School of Pharmacy, Tianjin Medical University, Tianjin 300070, China.<br /><searchLink fieldCode="AU" term="%22Jin+Z%22">Jin Z</searchLink>; Luzhou City Hospital of Traditional Chinese Medicine, Luzhou 646000, China.<br /><searchLink fieldCode="AU" term="%22Long+X%22">Long X</searchLink>; Department of Pathology, The affiliated Hospital, Southwest Medical University, Luzhou 646000, China.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Tianjin Key Laboratory of Technologies Enabling Development of Clinical Therapeutics and Diagnosis, School of Pharmacy, Tianjin Medical University, Tianjin 300070, China.<br /><searchLink fieldCode="AU" term="%22Yang+Z%22">Yang Z</searchLink>; Department of Pathology, The affiliated Hospital, Southwest Medical University, Luzhou 646000, China.<br /><searchLink fieldCode="AU" term="%22Dong+C%22">Dong C</searchLink>; Tianjin Key Laboratory of Technologies Enabling Development of Clinical Therapeutics and Diagnosis, School of Pharmacy, Tianjin Medical University, Tianjin 300070, China.<br /><searchLink fieldCode="AU" term="%22Tao+N%22">Tao N</searchLink>; Department of Pathology, The affiliated Hospital, Southwest Medical University, Luzhou 646000, China.; Key Laboratory of Epigenetic Regulation and Intervention, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
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      – Type: doi
        Value: 10.1021/acs.jafc.6c00481
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      – Code: eng
        Text: English
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        StartPage: 20430
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      – TitleFull: Glucans from Lentinus edodes Inhibit Myeloid-Derived Suppressor Cell-Induced Regulatory T Cells via the TLR4-TAK1-JNK Signaling Pathway to Scavenge Reactive Oxygen Species.
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            – D: 08
              M: 07
              Text: 2026 Jul 08
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              Y: 2026
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