Interrupting a mitochondrial DNA-driven innate immune circuit attenuates hepatic tissue remodeling and fibrotic architecture in experimental steatohepatitis.
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| Title: | Interrupting a mitochondrial DNA-driven innate immune circuit attenuates hepatic tissue remodeling and fibrotic architecture in experimental steatohepatitis. |
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| Authors: | Hamad RS; Biological Sciences Department, College of Science, King Faisal University, Al Ahsa 31982, Saudi Arabia. Electronic address: rhamad@kfu.edu.sa., Mohammed SA; Department of Basic sciences, College of Pharmacy, Al-Turath University, Baghdad, Iraq. Electronic address: sura.akram@uoturath.edu.iq., Hasan WA; Department of Basic sciences, College of Dentistry, Tikrit University, Tikrit, Iraq. Electronic address: waj7@tu.edu.iq., AbuoHashish NA; Pharmacology Department, Faculty of Medicine, Tanta University, Egypt. Electronic address: nourhan.abohashesh@med.tanta.edu.eg., El Afify SR; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alsalam University, Algharbia, Egypt. Electronic address: shereen.affify@sue.edu.eg., Ali MAM; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia. Electronic address: mamzaid@imamu.edu.sa., Mohamed AEA; Department of Pharmacology, Faculty of Medicine, Al-Azhar University, New Damietta 34517, Egypt; Department of Pharmacology, Faculty of Medicine, New Mansoura University, Egypt. Electronic address: Alaa.eisa.pharma@domazhermedicine.edu.eg., El-Kott AF; Department of Biology, College of Science, King Khalid University, Abha 61421, Saudi Arabia; Department of Zoology, Faculty of Science, Damanhour University, Damanhour, Egypt. Electronic address: elkottaf@kku.edu.sa., AlShehri MA; Department of Biology, College of Science, King Khalid University, Abha 61421, Saudi Arabia. Electronic address: mshehri@kku.edu.sa., Morsy K; Department of Biology, College of Science, King Khalid University, Abha 61421, Saudi Arabia. Electronic address: kasayed@kku.edu.sa., Farrag AA; Department of Histology and Cell Biology, Faculty of Medicine, Assiut University, Assiut 71515, Egypt.. Electronic address: alshaima@aun.edu.eg., Salem KM; Department of Internal Medicine, Faculty of Medicine, Fayoum University, Fayoum, Egypt. Electronic address: kms11@fayoum.edu.eg., Morsy NE; Faculty of Medicine, Mansoura University, Mansoura, Egypt. Electronic address: neselmorsy@mans.edu.eg., Elmowafy R; Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Mansoura University, Egypt; Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Horus University, Egypt. Electronic address: dr_rasha83@mans.edu.eg., Elmetwally AA; Department of Clinical Pharmacology, Faculty of Medicine, Mansoura University, Egypt. Electronic address: elmohager@mans.edu.eg., Ahmed WMS; Department of Medical Physiology, Faculty of Medicine, Al-Azhar University, Damietta, Egypt. Electronic address: walidkasem123456@domazhermedicine.edu.eg., Jamil L; Department of Histology, Faculty of Medicine, October 6 University (O6U), Giza, Egypt. Electronic address: lubnajamil.med@o6u.edu.eg., Shata A; Department of Basic Medical Sciences, Faculty of Medicine, Mansoura University, Egypt. Electronic address: ahmedmhes@mans.edu.eg., Chaudhary AA; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia. Electronic address: aachaudhary@imamu.edu.sa., Eissa H; Department of Pharmacology, College of Medicine, University of Bisha, Bisha 61922, Saudi Arabia.. Electronic address: hibrahim@ub.edu.sa., Saber S; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa 11152, Egypt. Electronic address: sameh.saber@deltauniv.edu.eg. |
| Source: | Tissue & cell [Tissue Cell] 2026 Jun 24; Vol. 103, pp. 103733. Date of Electronic Publication: 2026 Jun 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 0214745 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3072 (Electronic) Linking ISSN: 00408166 NLM ISO Abbreviation: Tissue Cell Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42361412 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Interrupting a mitochondrial DNA-driven innate immune circuit attenuates hepatic tissue remodeling and fibrotic architecture in experimental steatohepatitis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Hamad+RS%22">Hamad RS</searchLink>; Biological Sciences Department, College of Science, King Faisal University, Al Ahsa 31982, Saudi Arabia. Electronic address: rhamad@kfu.edu.sa.<br /><searchLink fieldCode="AU" term="%22Mohammed+SA%22">Mohammed SA</searchLink>; Department of Basic sciences, College of Pharmacy, Al-Turath University, Baghdad, Iraq. Electronic address: sura.akram@uoturath.edu.iq.<br /><searchLink fieldCode="AU" term="%22Hasan+WA%22">Hasan WA</searchLink>; Department of Basic sciences, College of Dentistry, Tikrit University, Tikrit, Iraq. Electronic address: waj7@tu.edu.iq.<br /><searchLink fieldCode="AU" term="%22AbuoHashish+NA%22">AbuoHashish NA</searchLink>; Pharmacology Department, Faculty of Medicine, Tanta University, Egypt. Electronic address: nourhan.abohashesh@med.tanta.edu.eg.<br /><searchLink fieldCode="AU" term="%22El+Afify+SR%22">El Afify SR</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alsalam University, Algharbia, Egypt. Electronic address: shereen.affify@sue.edu.eg.<br /><searchLink fieldCode="AU" term="%22Ali+MAM%22">Ali MAM</searchLink>; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia. Electronic address: mamzaid@imamu.edu.sa.<br /><searchLink fieldCode="AU" term="%22Mohamed+AEA%22">Mohamed AEA</searchLink>; Department of Pharmacology, Faculty of Medicine, Al-Azhar University, New Damietta 34517, Egypt; Department of Pharmacology, Faculty of Medicine, New Mansoura University, Egypt. Electronic address: Alaa.eisa.pharma@domazhermedicine.edu.eg.<br /><searchLink fieldCode="AU" term="%22El-Kott+AF%22">El-Kott AF</searchLink>; Department of Biology, College of Science, King Khalid University, Abha 61421, Saudi Arabia; Department of Zoology, Faculty of Science, Damanhour University, Damanhour, Egypt. Electronic address: elkottaf@kku.edu.sa.<br /><searchLink fieldCode="AU" term="%22AlShehri+MA%22">AlShehri MA</searchLink>; Department of Biology, College of Science, King Khalid University, Abha 61421, Saudi Arabia. Electronic address: mshehri@kku.edu.sa.<br /><searchLink fieldCode="AU" term="%22Morsy+K%22">Morsy K</searchLink>; Department of Biology, College of Science, King Khalid University, Abha 61421, Saudi Arabia. Electronic address: kasayed@kku.edu.sa.<br /><searchLink fieldCode="AU" term="%22Farrag+AA%22">Farrag AA</searchLink>; Department of Histology and Cell Biology, Faculty of Medicine, Assiut University, Assiut 71515, Egypt.. Electronic address: alshaima@aun.edu.eg.<br /><searchLink fieldCode="AU" term="%22Salem+KM%22">Salem KM</searchLink>; Department of Internal Medicine, Faculty of Medicine, Fayoum University, Fayoum, Egypt. Electronic address: kms11@fayoum.edu.eg.<br /><searchLink fieldCode="AU" term="%22Morsy+NE%22">Morsy NE</searchLink>; Faculty of Medicine, Mansoura University, Mansoura, Egypt. Electronic address: neselmorsy@mans.edu.eg.<br /><searchLink fieldCode="AU" term="%22Elmowafy+R%22">Elmowafy R</searchLink>; Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Mansoura University, Egypt; Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Horus University, Egypt. Electronic address: dr&#95;rasha83@mans.edu.eg.<br /><searchLink fieldCode="AU" term="%22Elmetwally+AA%22">Elmetwally AA</searchLink>; Department of Clinical Pharmacology, Faculty of Medicine, Mansoura University, Egypt. Electronic address: elmohager@mans.edu.eg.<br /><searchLink fieldCode="AU" term="%22Ahmed+WMS%22">Ahmed WMS</searchLink>; Department of Medical Physiology, Faculty of Medicine, Al-Azhar University, Damietta, Egypt. Electronic address: walidkasem123456@domazhermedicine.edu.eg.<br /><searchLink fieldCode="AU" term="%22Jamil+L%22">Jamil L</searchLink>; Department of Histology, Faculty of Medicine, October 6 University (O6U), Giza, Egypt. Electronic address: lubnajamil.med@o6u.edu.eg.<br /><searchLink fieldCode="AU" term="%22Shata+A%22">Shata A</searchLink>; Department of Basic Medical Sciences, Faculty of Medicine, Mansoura University, Egypt. Electronic address: ahmedmhes@mans.edu.eg.<br /><searchLink fieldCode="AU" term="%22Chaudhary+AA%22">Chaudhary AA</searchLink>; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia. Electronic address: aachaudhary@imamu.edu.sa.<br /><searchLink fieldCode="AU" term="%22Eissa+H%22">Eissa H</searchLink>; Department of Pharmacology, College of Medicine, University of Bisha, Bisha 61922, Saudi Arabia.. Electronic address: hibrahim@ub.edu.sa.<br /><searchLink fieldCode="AU" term="%22Saber+S%22">Saber S</searchLink>; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa 11152, Egypt. Electronic address: sameh.saber@deltauniv.edu.eg. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220214745%22">Tissue & cell</searchLink> [Tissue Cell] 2026 Jun 24; Vol. 103, pp. 103733. <i>Date of Electronic Publication: </i>2026 Jun 24. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Churchill+Livingstone%22">Churchill Livingstone </searchLink><i>Country of Publication: </i>Scotland <i>NLM ID: </i>0214745 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-3072 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200408166%22">00408166 </searchLink><i>NLM ISO Abbreviation: </i>Tissue Cell <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42361412 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.tice.2026.103733 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 103733 Titles: – TitleFull: Interrupting a mitochondrial DNA-driven innate immune circuit attenuates hepatic tissue remodeling and fibrotic architecture in experimental steatohepatitis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hamad RS – PersonEntity: Name: NameFull: Mohammed SA – PersonEntity: Name: NameFull: Hasan WA – PersonEntity: Name: NameFull: AbuoHashish NA – PersonEntity: Name: NameFull: El Afify SR – PersonEntity: Name: NameFull: Ali MAM – PersonEntity: Name: NameFull: Mohamed AEA – PersonEntity: Name: NameFull: El-Kott AF – PersonEntity: Name: NameFull: AlShehri MA – PersonEntity: Name: NameFull: Morsy K – PersonEntity: Name: NameFull: Farrag AA – PersonEntity: Name: NameFull: Salem KM – PersonEntity: Name: NameFull: Morsy NE – PersonEntity: Name: NameFull: Elmowafy R – PersonEntity: Name: NameFull: Elmetwally AA – PersonEntity: Name: NameFull: Ahmed WMS – PersonEntity: Name: NameFull: Jamil L – PersonEntity: Name: NameFull: Shata A – PersonEntity: Name: NameFull: Chaudhary AA – PersonEntity: Name: NameFull: Eissa H – PersonEntity: Name: NameFull: Saber S IsPartOfRelationships: – BibEntity: Dates: – D: 24 M: 06 Text: 2026 Jun 24 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1532-3072 Numbering: – Type: volume Value: 103 Titles: – TitleFull: Tissue & cell Type: main |
| ResultId | 1 |
