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TDCPP induces ferroptosis in THP-1 macrophages through mitochondrial regulation of Fe2 + homeostasis.

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Title: TDCPP induces ferroptosis in THP-1 macrophages through mitochondrial regulation of Fe2 + homeostasis.
Authors: Wang S; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore; NUS Center for Cancer Research (N2CR), Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore., Shi C; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore; NUS Center for Cancer Research (N2CR), Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore., Lai R; Department of Infection Control, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei Province, China., Wang C; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China. Electronic address: wangchen0227@shu.edu.cn., Zeng L; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China., Peng Y; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China., Hang M; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China., Zheng Y; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China., Qiao X; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China., Xuan Q; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China., Chen C; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China. Electronic address: chaochen@shu.edu.cn., Kumar AP; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore; NUS Center for Cancer Research (N2CR), Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore., Li H; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China. Electronic address: huili2018@shu.edu.cn.
Source: Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2026 Aug; Vol. 321, pp. 120432. Date of Electronic Publication: 2026 Jun 26.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7805381 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2414 (Electronic) Linking ISSN: 01476513 NLM ISO Abbreviation: Ecotoxicol Environ Saf Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: TDCPP induces ferroptosis in THP-1 macrophages through mitochondrial regulation of Fe<superscript>2 +</superscript> homeostasis.
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  Data: <searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore; NUS Center for Cancer Research (N2CR), Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Shi+C%22">Shi C</searchLink>; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore; NUS Center for Cancer Research (N2CR), Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Lai+R%22">Lai R</searchLink>; Department of Infection Control, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei Province, China.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China. Electronic address: wangchen0227@shu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zeng+L%22">Zeng L</searchLink>; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China.<br /><searchLink fieldCode="AU" term="%22Peng+Y%22">Peng Y</searchLink>; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China.<br /><searchLink fieldCode="AU" term="%22Hang+M%22">Hang M</searchLink>; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China.<br /><searchLink fieldCode="AU" term="%22Zheng+Y%22">Zheng Y</searchLink>; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China.<br /><searchLink fieldCode="AU" term="%22Qiao+X%22">Qiao X</searchLink>; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China.<br /><searchLink fieldCode="AU" term="%22Xuan+Q%22">Xuan Q</searchLink>; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China.<br /><searchLink fieldCode="AU" term="%22Chen+C%22">Chen C</searchLink>; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China. Electronic address: chaochen@shu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Kumar+AP%22">Kumar AP</searchLink>; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore; NUS Center for Cancer Research (N2CR), Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China. Electronic address: huili2018@shu.edu.cn.
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        Value: 10.1016/j.ecoenv.2026.120432
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              Text: 2026 Aug
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              Y: 2026
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